Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FVF73_RS09780 Genome accession   NZ_CP042934
Coordinates   1987152..1987808 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli 042     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1982152..1992808
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVF73_RS09750 (FVF73_09750) yecA 1983403..1984068 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FVF73_RS09770 (FVF73_09770) pgsA 1984718..1985266 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FVF73_RS09775 (FVF73_09775) uvrC 1985323..1987155 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FVF73_RS09780 (FVF73_09780) letA 1987152..1987808 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FVF73_RS24215 - 1987950..1988021 (+) 72 Protein_1915 transcriptional regulator -
  FVF73_RS09785 (FVF73_09785) yecU 1988104..1988280 (+) 177 WP_000590347.1 protein YecU -
  FVF73_RS09790 (FVF73_09790) yecF 1988267..1988491 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FVF73_RS09795 (FVF73_09795) sdiA 1988558..1989280 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  FVF73_RS09800 (FVF73_09800) tcyN 1989510..1990262 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FVF73_RS09805 (FVF73_09805) tcyL 1990259..1990927 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FVF73_RS09810 (FVF73_09810) dcyD 1990942..1991928 (-) 987 WP_046659907.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=333113 FVF73_RS09780 WP_000611335.1 1987152..1987808(-) (letA) [Escherichia coli 042]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=333113 FVF73_RS09780 WP_000611335.1 1987152..1987808(-) (letA) [Escherichia coli 042]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486