Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SP70585_RS02195 Genome accession   NC_012468
Coordinates   400707..401396 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae 70585     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 395707..406396
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SP70585_RS02170 (SP70585_0443) gpsB 395817..396146 (+) 330 WP_000146522.1 cell division regulator GpsB -
  SP70585_RS02180 (SP70585_0444) - 396632..397789 (+) 1158 WP_000711388.1 class I SAM-dependent RNA methyltransferase -
  SP70585_RS02185 (SP70585_0445) mapZ 397801..399195 (+) 1395 WP_000039305.1 mid-cell-anchored protein MapZ -
  SP70585_RS02190 (SP70585_0446) gndA 399271..400695 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  SP70585_RS02195 (SP70585_0447) covR 400707..401396 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  SP70585_RS02200 (SP70585_0448) cbpC 401494..402513 (+) 1020 WP_000771111.1 choline-binding protein CbpC -
  SP70585_RS02205 (SP70585_0449) - 402631..403863 (-) 1233 WP_000765682.1 MFS transporter -
  SP70585_RS13055 - 404022..404492 (-) 471 WP_001809487.1 lanthionine synthetase LanC family protein -
  SP70585_RS14115 (SP70585_0450) - 404392..404730 (-) 339 WP_001820155.1 lanthionine synthetase LanC family protein -
  SP70585_RS02215 - 405393..405722 (+) 330 WP_000196970.1 transposase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=33291 SP70585_RS02195 WP_000518018.1 400707..401396(+) (covR) [Streptococcus pneumoniae 70585]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=33291 SP70585_RS02195 WP_000518018.1 400707..401396(+) (covR) [Streptococcus pneumoniae 70585]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment