Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CA902_RS09310 Genome accession   NZ_CP042896
Coordinates   1976907..1977563 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CFSAN061771     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1971907..1982563
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA902_RS09280 (CA902_009375) dcyD 1972787..1973773 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  CA902_RS09285 (CA902_009380) tcyL 1973788..1974456 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  CA902_RS09290 (CA902_009385) tcyN 1974453..1975205 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CA902_RS09295 (CA902_009390) sdiA 1975435..1976157 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  CA902_RS09300 (CA902_009395) yecF 1976224..1976448 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  CA902_RS09305 (CA902_009400) yecU 1976435..1976611 (-) 177 WP_001307856.1 protein YecU -
  CA902_RS09310 (CA902_009405) letA 1976907..1977563 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CA902_RS09315 (CA902_009410) uvrC 1977560..1979392 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  CA902_RS09320 (CA902_009415) pgsA 1979449..1979997 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CA902_RS09340 (CA902_009435) - 1980695..1981336 (-) 642 Protein_1830 hypothetical protein -
  CA902_RS09345 (CA902_009440) - 1981409..1982497 (+) 1089 Protein_1831 IS3 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=332727 CA902_RS09310 WP_000611328.1 1976907..1977563(+) (letA) [Escherichia coli strain CFSAN061771]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=332727 CA902_RS09310 WP_000611328.1 1976907..1977563(+) (letA) [Escherichia coli strain CFSAN061771]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482

Multiple sequence alignment