Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CA901_RS09010 Genome accession   NZ_CP042893
Coordinates   1884487..1885143 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain CFSAN061772     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1879487..1890143
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CA901_RS08980 (CA901_009010) dcyD 1880366..1881352 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  CA901_RS08985 (CA901_009015) tcyL 1881367..1882035 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  CA901_RS08990 (CA901_009020) tcyN 1882032..1882784 (+) 753 WP_001273015.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CA901_RS08995 (CA901_009025) sdiA 1883014..1883736 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  CA901_RS09000 (CA901_009030) yecF 1883804..1884028 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  CA901_RS09005 (CA901_009035) yecU 1884015..1884191 (-) 177 WP_000590344.1 protein YecU -
  CA901_RS24790 (CA901_009040) - 1884229..1884345 (-) 117 WP_001302039.1 hypothetical protein -
  CA901_RS09010 (CA901_009045) letA 1884487..1885143 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CA901_RS09015 (CA901_009050) uvrC 1885140..1886972 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  CA901_RS09020 (CA901_009055) pgsA 1887029..1887577 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CA901_RS09040 (CA901_009075) yecA 1888227..1888892 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=332647 CA901_RS09010 WP_000611328.1 1884487..1885143(+) (letA) [Escherichia coli strain CFSAN061772]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=332647 CA901_RS09010 WP_000611328.1 1884487..1885143(+) (letA) [Escherichia coli strain CFSAN061772]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482