Detailed information NTG0033227

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: SPP_RS04860
• Genome accession: NC_012467
• Coordinates: 901313..902266 (+)
• Length: 317 a.a.
• NCBI ID: WP_000495909.1
• Uniprot ID: A0A0H2UPP6
• Organism: Streptococcus pneumoniae P1031
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 896313..907266

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPP_RS04835 (SPP_0979)	rpmG	897056..897205 (+)	150	WP_001809104.1	50S ribosomal protein L33	-
SPP_RS04840 (SPP_0980)	secG	897245..897478 (+)	234	WP_000282517.1	preprotein translocase subunit SecG	-
SPP_RS04845 (SPP_0981)	rnr	897580..899934 (+)	2355	WP_000654877.1	ribonuclease R	-
SPP_RS04850 (SPP_0982)	smpB	899897..900364 (+)	468	WP_001051753.1	SsrA-binding protein SmpB	-
SPP_RS04855 (SPP_0983)	tehB	900380..901240 (+)	861	WP_000413758.1	SAM-dependent methyltransferase TehB	-
SPP_RS04860 (SPP_0984)	coiA	901313..902266 (+)	954	WP_000495909.1	competence protein CoiA	Machinery gene
SPP_RS04865 (SPP_0985)	pepF	902285..904087 (+)	1803	WP_000244122.1	oligoendopeptidase F	Regulator
SPP_RS04870 (SPP_0986)	-	904089..904802 (+)	714	WP_000230399.1	O-methyltransferase	-
SPP_RS04875 (SPP_0987)	prsA	904869..905810 (+)	942	WP_000727933.1	peptidylprolyl isomerase PrsA	-
SPP_RS04880 (SPP_0988)	-	905927..906268 (-)	342	Protein_932	transposase	-
SPP_RS12680	-	906681..906776 (+)	96	Protein_933	IS630 family transposase	-

Sequence

Protein

• Length: 317 a.a.
• Molecular weight: 38243.86 Da
• Isoelectric Point: 8.9865

>NTDB_id=33227 SPP_RS04860 WP_000495909.1 901313..902266(+) (coiA) [Streptococcus pneumoniae P1031]
MFVARDARGELVNVLEDKLEKQAYTCPACGGQLHLRQGPSVRTHFAHKSLKDCDFFFENESPEHLANKESLYHWLKKETK
VQLEYPLSELKQIADVFVNGNLALEVQCSPLPQKVLKERSEGYRSQGYQVLWLLGQKLWLKERLTRLQQGFLYFSQNMGF
YVWELDKEKQVLRLKYLIYQDLRGKLHYQIKEFSYGQGSLLEILRLPYKRQKISHFTVSEDKDICRYIRQQLYYQNLFWM
KEQAEAYQKGENILTYGLKEWYPQIRPIVGKFFQIEQDLTSYYQHFYTYYQKNPQNDWQKLYPPAFYQQYFLKNMVE

Nucleotide

• Length: 954 bp

>NTDB_id=33227 SPP_RS04860 WP_000495909.1 901313..902266(+) (coiA) [Streptococcus pneumoniae P1031]
ATGTTTGTTGCGAGAGATGCTAGGGGAGAATTGGTAAATGTGTTAGAGGATAAACTTGAGAAGCAAGCATACACCTGCCC
AGCTTGTGGAGGCCAGCTCCATTTGCGTCAAGGACCAAGTGTACGGACGCATTTTGCCCATAAATCCTTAAAAGACTGTG
ATTTTTTCTTTGAAAATGAAAGTCCAGAACACCTGGCCAATAAGGAATCCCTCTATCACTGGTTGAAAAAAGAGACAAAG
GTTCAATTAGAGTACCCGCTTTCAGAACTTAAACAGATTGCGGATGTATTTGTAAATGGCAATCTAGCTCTAGAAGTTCA
GTGTAGTCCCTTGCCTCAGAAAGTCCTTAAAGAGCGAAGTGAGGGATATCGTAGTCAGGGTTACCAAGTACTGTGGTTGC
TGGGTCAAAAACTGTGGCTCAAGGAGCGTTTGACTCGTCTACAGCAAGGTTTTCTTTATTTCAGTCAAAACATGGGCTTT
TATGTTTGGGAATTAGACAAGGAAAAACAAGTTTTAAGACTCAAATACCTGATTTACCAGGATCTCCGCGGTAAACTCCA
TTATCAAATCAAGGAATTTTCCTATGGTCAAGGTAGTTTATTGGAAATATTGCGTCTTCCCTATAAGAGACAAAAAATAT
CTCATTTTACAGTTTCTGAGGACAAGGACATCTGTCGCTATATCCGGCAACAACTTTATTATCAAAATCTCTTTTGGATG
AAAGAACAAGCAGAAGCCTATCAAAAGGGAGAAAATATCCTGACTTATGGACTGAAAGAATGGTATCCACAAATTCGACC
AATAGTGGGCAAATTTTTCCAGATTGAACAAGACTTGACTAGCTATTATCAGCACTTTTATACCTATTACCAAAAAAATC
CTCAAAATGATTGGCAAAAGCTTTATCCACCAGCCTTTTATCAGCAATATTTCTTGAAAAATATGGTAGAATAG

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (13-263)

3D structure

• AlphaFold DB: A0A0H2UPP6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Streptococcus pneumoniae TIGR4	100	100	1
coiA	Streptococcus pneumoniae Rx1	99.369	100	0.994
coiA	Streptococcus pneumoniae D39	99.369	100	0.994
coiA	Streptococcus pneumoniae R6	99.369	100	0.994
coiA	Streptococcus mitis NCTC 12261	89.274	100	0.893
coiA	Lactococcus lactis subsp. cremoris KW2	42.593	100	0.435