Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FVE20_RS13215 Genome accession   NZ_CP042846
Coordinates   2693422..2694078 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain JME64     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2688422..2699078
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVE20_RS13185 yecA 2689673..2690338 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FVE20_RS13205 pgsA 2690988..2691536 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FVE20_RS13210 uvrC 2691593..2693425 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FVE20_RS13215 letA 2693422..2694078 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FVE20_RS23070 - 2694220..2694291 (+) 72 Protein_2586 transcriptional regulator -
  FVE20_RS13220 yecU 2694374..2694550 (+) 177 WP_000590347.1 protein YecU -
  FVE20_RS13225 yecF 2694537..2694761 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FVE20_RS13230 sdiA 2694829..2695551 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  FVE20_RS13235 tcyN 2695781..2696533 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FVE20_RS13240 tcyL 2696530..2697198 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FVE20_RS13245 dcyD 2697213..2698199 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=332243 FVE20_RS13215 WP_000611335.1 2693422..2694078(-) (letA) [Escherichia coli strain JME64]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=332243 FVE20_RS13215 WP_000611335.1 2693422..2694078(-) (letA) [Escherichia coli strain JME64]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment