Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   SPP_RS02060 Genome accession   NC_012467
Coordinates   370468..371157 (+) Length   229 a.a.
NCBI ID   WP_000518018.1    Uniprot ID   -
Organism   Streptococcus pneumoniae P1031     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 365468..376157
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPP_RS02035 (SPP_0410) gpsB 365577..365906 (+) 330 WP_000146522.1 cell division regulator GpsB -
  SPP_RS02045 (SPP_0411) - 366392..367549 (+) 1158 WP_000711391.1 class I SAM-dependent RNA methyltransferase -
  SPP_RS02050 (SPP_0412) mapZ 367562..368956 (+) 1395 WP_000039273.1 mid-cell-anchored protein MapZ -
  SPP_RS02055 (SPP_0413) gndA 369032..370456 (+) 1425 WP_000158781.1 NADP-dependent phosphogluconate dehydrogenase -
  SPP_RS02060 (SPP_0414) covR 370468..371157 (+) 690 WP_000518018.1 response regulator transcription factor Regulator
  SPP_RS02065 (SPP_0415) cbpC 371255..372274 (+) 1020 WP_000771110.1 choline-binding protein CbpC -
  SPP_RS02070 (SPP_0416) - 372392..373624 (-) 1233 WP_000765670.1 MFS transporter -
  SPP_RS02075 (SPP_0417) - 373784..374254 (-) 471 WP_001844742.1 lanthionine synthetase LanC family protein -
  SPP_RS13965 - 374154..374492 (-) 339 Protein_398 lanthionine synthetase LanC family protein -
  SPP_RS02080 (SPP_0418) - 375362..375484 (+) 123 Protein_399 cell wall-binding protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26898.22 Da        Isoelectric Point: 6.9836

>NTDB_id=33213 SPP_RS02060 WP_000518018.1 370468..371157(+) (covR) [Streptococcus pneumoniae P1031]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLMLLNVNLGDMMAQDFAEKLSRTKPASVIMIL
DHWEDLQEELEVVQRFAVSYIYKPVLIENLVARISAIFRGRDFIDQHCSLMKVPRTYRNLRIDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=33213 SPP_RS02060 WP_000518018.1 370468..371157(+) (covR) [Streptococcus pneumoniae P1031]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTAGCTCATTTTTTAAGTTTGGAACTCCAGAAAGAGCAGTA
TCGGGTTGATCTGGTAGAGGAGGGGCAAAAAGCCCTCTCCATGGCTCTTCAGACAGACTATGATTTGATGTTATTGAACG
TTAATCTGGGAGATATGATGGCTCAGGATTTTGCAGAAAAATTGAGTCGAACTAAACCTGCCTCAGTCATCATGATTTTA
GATCATTGGGAAGACTTGCAAGAAGAGCTGGAAGTTGTTCAGCGTTTTGCAGTTTCATACATTTATAAGCCAGTCCTTAT
CGAAAATCTGGTAGCGCGTATTTCGGCGATCTTCCGAGGTCGGGACTTCATTGATCAACACTGCAGTCTGATGAAAGTTC
CAAGGACCTACCGCAATCTTAGGATAGATGTTGAACATCACACGGTTTATCGTGGTGAAGAGATGATTGCTCTGACCCGC
CGTGAGTATGACCTTTTGGCGACACTTATGGGAAGCAAGAAAGTATTGACTCGTGAGCAATTGTTGGAAAGTGTTTGGAA
GTATGAAAGTGCGACCGAGACAAATATCGTAGATGTCTATATCCGCTATCTACGGAGCAAGCTTGATGTTAAAGGCCAAA
AAAGCTACATTAAAACCGTGCGTGGTGTTGGATATACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.826

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

100

0.463

Multiple sequence alignment