Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FVE23_RS13270 Genome accession   NZ_CP042843
Coordinates   2703416..2704072 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain JME67     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2698416..2709072
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FVE23_RS13240 yecA 2699667..2700332 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FVE23_RS13260 pgsA 2700982..2701530 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FVE23_RS13265 uvrC 2701587..2703419 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FVE23_RS13270 letA 2703416..2704072 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FVE23_RS23110 - 2704214..2704285 (+) 72 Protein_2597 transcriptional regulator -
  FVE23_RS13275 yecU 2704368..2704544 (+) 177 WP_000590347.1 protein YecU -
  FVE23_RS13280 yecF 2704531..2704755 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FVE23_RS13285 sdiA 2704823..2705545 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  FVE23_RS13290 tcyN 2705775..2706527 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FVE23_RS13295 tcyL 2706524..2707192 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FVE23_RS13300 dcyD 2707207..2708193 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=331997 FVE23_RS13270 WP_000611335.1 2703416..2704072(-) (letA) [Escherichia coli strain JME67]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=331997 FVE23_RS13270 WP_000611335.1 2703416..2704072(-) (letA) [Escherichia coli strain JME67]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486

Multiple sequence alignment