Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EHW89_RS06900 Genome accession   NZ_CP034543
Coordinates   1414528..1415217 (-) Length   229 a.a.
NCBI ID   WP_018543712.1    Uniprot ID   A0A3E5D5Y8
Organism   Streptococcus periodonticum strain KCOM 2412     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1409528..1420217
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHW89_RS06880 (EHW89_06880) nrdR 1409980..1410453 (-) 474 WP_022526962.1 transcriptional regulator NrdR -
  EHW89_RS06885 (EHW89_06885) - 1410619..1411248 (+) 630 WP_022526963.1 hypothetical protein -
  EHW89_RS06890 (EHW89_06890) - 1411295..1412110 (-) 816 WP_057489789.1 endonuclease/exonuclease/phosphatase family protein -
  EHW89_RS06895 (EHW89_06895) - 1412127..1414316 (-) 2190 WP_106100732.1 PTS transporter subunit IIBC -
  EHW89_RS06900 (EHW89_06900) covR 1414528..1415217 (-) 690 WP_018543712.1 response regulator transcription factor Regulator
  EHW89_RS06905 (EHW89_06905) gndA 1415226..1416650 (-) 1425 WP_126467505.1 NADP-dependent phosphogluconate dehydrogenase -
  EHW89_RS06910 (EHW89_06910) - 1416742..1417278 (-) 537 WP_126468081.1 DUF177 domain-containing protein -
  EHW89_RS06915 (EHW89_06915) - 1417471..1418700 (+) 1230 WP_126467507.1 transporter -
  EHW89_RS06920 (EHW89_06920) htpX 1418798..1419694 (-) 897 WP_126467509.1 zinc metalloprotease HtpX -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26444.50 Da        Isoelectric Point: 6.2732

>NTDB_id=331789 EHW89_RS06900 WP_018543712.1 1414528..1415217(-) (covR) [Streptococcus periodonticum strain KCOM 2412]
MAKRILLVEKEKKLAQFIGLELQKEGYRVDLFETGKDALASARANQYDLFLLNFMLDDMTGTEFAAQLSVIKPASVIIVL
DNRDNILQYTEEIQRFAVAYMVEPFIVTDLVEKISAIFRGRDFIDQHCSQMKVPTSYRNLRIDVQNHTVYRGEEVIALTR
REYDLLATLMGSHQALSREQLLERVWKYEGAVETNVVDVYIRYLRSKIDIAGQKSYIKTVRGVGYAMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=331789 EHW89_RS06900 WP_018543712.1 1414528..1415217(-) (covR) [Streptococcus periodonticum strain KCOM 2412]
ATGGCGAAGCGGATTTTATTAGTTGAGAAAGAAAAAAAATTAGCGCAATTTATTGGCTTAGAGCTACAAAAAGAAGGTTA
TCGAGTTGATCTTTTTGAAACAGGAAAAGATGCTTTGGCGTCTGCGAGAGCTAATCAATACGATTTATTCCTGTTGAATT
TTATGCTTGACGATATGACAGGAACAGAATTTGCCGCACAATTAAGTGTGATAAAGCCTGCTTCGGTCATCATTGTATTG
GATAATCGTGATAATATTCTTCAATATACTGAGGAAATCCAACGCTTTGCTGTTGCTTACATGGTAGAACCATTCATTGT
GACGGACTTAGTTGAAAAAATTTCTGCCATTTTTCGTGGGCGTGATTTTATTGACCAGCATTGTAGTCAGATGAAAGTTC
CAACATCTTATCGGAATCTTCGGATTGATGTGCAAAATCATACAGTTTATCGAGGTGAAGAAGTGATTGCTTTGACTCGA
AGAGAGTATGATTTATTAGCAACATTGATGGGAAGTCATCAGGCTTTAAGCCGTGAACAGTTGTTAGAACGCGTGTGGAA
ATACGAAGGAGCTGTTGAAACAAATGTTGTCGATGTTTATATTCGCTATCTTCGTAGTAAAATTGATATAGCGGGGCAAA
AAAGTTATATAAAAACCGTGCGTGGTGTTGGTTATGCTATGCAAGAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3E5D5Y8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

48.261

100

0.485
  covR Lactococcus lactis subsp. lactis strain DGCC12653

45.415

100

0.454

Multiple sequence alignment