Detailed information NTG0331684

Bioinformatically predicted

Overview

• Name: comP
• Type: Regulator
• Locus tag: EJJ34_RS17350
• Genome accession: NZ_CP034484
• Coordinates: 3248758..3251067 (-)
• Length: 769 a.a.
• NCBI ID: WP_003242894.1
• Uniprot ID: Q99027
• Organism: Bacillus subtilis subsp. subtilis NCIB 3610 = ATCC 6051 = DSM 10 strain NCIB 3610
• Function: phosphorylation of ComA (predicted from homology) Competence regulation

Genomic Context

Location: 3243758..3256067

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJJ34_RS17310 (EJJ34_17315)	mrpB	3244225..3244656 (+)	432	WP_003228819.1	Na(+)/H(+) antiporter subunit B	-
EJJ34_RS17315 (EJJ34_17320)	mrpC	3244656..3244997 (+)	342	WP_003220730.1	Na(+)/H(+) antiporter subunit C	-
EJJ34_RS17320 (EJJ34_17325)	mrpD	3244990..3246471 (+)	1482	WP_003244432.1	Na+/H+ antiporter subunit D	-
EJJ34_RS17325 (EJJ34_17330)	mrpE	3246477..3246953 (+)	477	WP_003244015.1	Na+/H+ antiporter subunit E	-
EJJ34_RS17330 (EJJ34_17335)	mrpF	3246953..3247237 (+)	285	WP_003228814.1	Na(+)/H(+) antiporter subunit F1	-
EJJ34_RS17335 (EJJ34_17340)	mnhG	3247221..3247595 (+)	375	WP_003244302.1	monovalent cation/H(+) antiporter subunit G	-
EJJ34_RS17340 (EJJ34_17345)	yuxO	3247634..3248014 (-)	381	WP_003228810.1	hotdog fold thioesterase	-
EJJ34_RS17345 (EJJ34_17350)	comA	3248033..3248677 (-)	645	WP_003220716.1	two-component system response regulator ComA	Regulator
EJJ34_RS17350 (EJJ34_17355)	comP	3248758..3251067 (-)	2310	WP_003242894.1	two-component system sensor histidine kinase ComP	Regulator
EJJ34_RS17355 (EJJ34_17360)	comX	3251082..3251249 (-)	168	WP_003242801.1	competence pheromone ComX	Regulator
EJJ34_RS17360 (EJJ34_17365)	comQ	3251237..3252136 (-)	900	WP_003243039.1	ComX modifying isoprenyl transferase ComQ	Regulator
EJJ34_RS17365 (EJJ34_17370)	degQ	3252321..3252461 (-)	141	WP_003220708.1	degradation enzyme regulation protein DegQ	Regulator
EJJ34_RS17370 (EJJ34_17375)	-	3252683..3252808 (+)	126	WP_003228793.1	hypothetical protein	-
EJJ34_RS17375 (EJJ34_17380)	-	3252922..3253290 (+)	369	WP_003243784.1	hypothetical protein	-
EJJ34_RS17380 (EJJ34_17385)	pdeH	3253266..3254487 (-)	1222	Protein_3333	cyclic di-GMP phosphodiesterase	-

Sequence

Protein

• Length: 769 a.a.
• Molecular weight: 89308.77 Da
• Isoelectric Point: 8.2618

>NTDB_id=331684 EJJ34_RS17350 WP_003242894.1 3248758..3251067(-) (comP) [Bacillus subtilis subsp. subtilis NCIB 3610 = ATCC 6051 = DSM 10 strain NCIB 3610]
MKNLIKKFTIAVIVLSILYISYTTYISMNGIIIGTKIHKNDKSQFMIEEISESSYGQFVGLRQGDIILKINKEKPSDKHL
KWGYLSHINSLDILRSGKKIHLKDFDLVTLNRPYSFFLFVLPLFFYFLSIICIFYILKVNKKRRSFAAYILILLLLDISI
AYISAGGPFRGHIINRYINLFTFISSPILYLQFIQRYLGEIGKTFLNRISFLYIIPIFNLGIEFFQDYLQVDIDFLATLN
LVSFATLTLFSFSAIYLHLNKYKYAEHSFILKLLILTNTLSFAPFLIFFVLPIIFTGNYIFPALASASLLVLIPFGLVYQ
FVANKMFDIEFILGRMRYYALLAMIPTLLIVGALVLFDVMDIQMNPVRQTVFFFVVMFAVFYFKEVMDFKFRLKRFSEKF
NYQDSIFKYTQLMRGVTSLQQVFKELKNTILDVLLVSKAYTFEVTPDHKVIFLDKHEVGPDWNFYQEEFENVTSEIGKII
EVNQGFLMKVGERGGSSYVLLCLSNINTPRLTRDEISWLKTLSFYTSVSMENVLHIEELMEHLKDLKQEGTNPIWLKKLM
FAIEEKQRSGLARDLHDSVLQDLISLKRQCELFLGDFKKDDNPCREEVQDKLVQMNEQMSDVISMTRETCHELRPQLLYD
LGLVKALSKLVAQQQERVPFHIRLNTGRFTASLDLDSQLNLYRIIQEFLSNAVKHSQATDVLIMLISIQNKIVLHYEDDG
VGFDQEKNTEHSMSMGLSGIKERVRALDGRLRIETSEGKGFKADIEIEL

Nucleotide

• Length: 2310 bp

>NTDB_id=331684 EJJ34_RS17350 WP_003242894.1 3248758..3251067(-) (comP) [Bacillus subtilis subsp. subtilis NCIB 3610 = ATCC 6051 = DSM 10 strain NCIB 3610]
TTGAAGAACTTAATAAAAAAATTCACAATAGCTGTAATTGTTTTGAGTATCCTTTATATAAGCTATACAACTTATATCAG
TATGAATGGAATTATTATTGGGACTAAGATTCATAAAAATGATAAAAGTCAATTTATGATAGAAGAAATATCGGAATCTT
CATATGGACAATTTGTTGGTCTGAGACAGGGAGACATCATATTAAAAATTAATAAAGAAAAACCTTCAGACAAACATTTG
AAATGGGGATATTTGAGTCATATTAACAGTCTGGATATTTTGAGAAGTGGAAAAAAGATTCATCTCAAAGATTTTGATTT
AGTTACTCTAAATAGACCTTATAGTTTTTTTCTGTTCGTACTTCCTTTGTTTTTTTATTTTTTAAGCATAATATGTATTT
TTTATATACTTAAAGTAAATAAAAAAAGGAGATCATTTGCTGCCTATATTCTTATTCTATTGTTATTAGACATTTCGATA
GCATATATAAGTGCAGGCGGACCATTTAGAGGACATATAATCAATCGGTATATTAACTTGTTTACTTTTATATCTTCTCC
TATTCTTTATCTTCAATTTATACAAAGATACCTTGGAGAAATAGGTAAAACTTTTTTGAATAGAATTTCTTTTCTTTATA
TCATACCAATATTTAATCTTGGTATTGAGTTTTTTCAAGACTATTTACAAGTAGATATTGATTTTTTAGCAACTCTTAAT
TTGGTTTCTTTTGCAACTTTGACTCTATTTTCTTTTTCAGCGATATACTTACATCTTAATAAATATAAATATGCTGAGCA
TTCGTTTATTCTTAAATTACTAATTTTAACAAACACTCTTTCATTTGCGCCTTTTTTGATATTTTTTGTTCTTCCAATAA
TATTTACAGGTAATTATATTTTCCCGGCATTAGCTTCGGCGTCATTACTAGTACTAATTCCGTTCGGGTTAGTATACCAA
TTTGTAGCCAATAAGATGTTTGATATAGAGTTTATCTTAGGAAGAATGAGATACTATGCTCTACTTGCCATGATACCAAC
TCTTCTAATAGTTGGTGCATTAGTTCTGTTTGATGTAATGGACATCCAGATGAACCCTGTGCGTCAAACTGTATTTTTTT
TCGTTGTCATGTTCGCTGTCTTTTATTTTAAAGAGGTCATGGATTTTAAATTTCGGTTAAAACGTTTCTCCGAAAAATTC
AACTATCAGGACAGTATTTTTAAATATACTCAGCTAATGAGGGGTGTAACTTCTCTTCAACAAGTTTTTAAAGAACTGAA
AAATACTATACTGGATGTTTTGCTTGTAAGCAAAGCTTATACCTTTGAGGTTACTCCTGATCACAAAGTGATATTTTTAG
ATAAGCATGAAGTTGGACCGGACTGGAATTTTTATCAAGAGGAATTTGAAAACGTAACTTCAGAAATTGGGAAAATTATA
GAAGTCAATCAAGGCTTTCTTATGAAAGTTGGTGAACGAGGCGGTAGTTCTTATGTTCTGCTTTGTTTATCTAATATTAA
CACTCCCCGGCTAACACGTGATGAAATATCGTGGCTGAAAACACTGTCTTTTTATACAAGTGTGTCCATGGAAAATGTCC
TGCATATTGAGGAGCTCATGGAACATTTGAAGGACTTAAAACAAGAGGGAACCAACCCCATCTGGCTGAAAAAGCTAATG
TTTGCAATCGAAGAAAAACAGCGTTCAGGACTCGCCCGCGATCTCCACGATTCGGTTCTTCAGGATTTGATTTCCTTAAA
ACGCCAGTGTGAGCTGTTTTTGGGTGATTTCAAGAAGGATGATAATCCGTGCCGTGAAGAGGTGCAGGACAAGCTTGTAC
AGATGAATGAGCAGATGTCTGATGTGATTTCGATGACGAGGGAGACGTGTCATGAGCTGCGGCCGCAGCTTCTGTATGAT
CTTGGATTGGTGAAGGCGCTGTCGAAGCTGGTGGCGCAGCAGCAGGAGCGGGTTCCGTTTCATATCCGTTTAAATACCGG
GAGATTTACGGCTTCCCTTGATCTGGATTCGCAGCTGAATTTGTACCGGATCATTCAAGAGTTTCTGTCTAATGCGGTCA
AGCACTCTCAGGCGACGGATGTGCTGATTATGCTCATCAGTATTCAAAACAAAATCGTTCTTCATTATGAGGACGATGGC
GTTGGGTTTGATCAAGAAAAAAATACTGAGCATTCCATGAGCATGGGGCTTTCTGGCATTAAGGAGAGAGTCAGGGCTTT
AGATGGGCGCCTTCGGATTGAAACAAGTGAAGGAAAGGGCTTTAAGGCTGATATTGAAATCGAATTGTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (568-638)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (679-765)

3D structure

• AlphaFold DB: Q99027

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Bacillus subtilis subsp. subtilis str. 168	100	100	1