Detailed information NTG0331509

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FGL89_RS02585
• Genome accession: NZ_CP042374
• Coordinates: 548285..550879 (-)
• Length: 864 a.a.
• NCBI ID: WP_014973956.1
• Uniprot ID: K0D978
• Organism: Leuconostoc carnosum strain CBA3620
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 543285..555879

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FGL89_RS02565 (FGL89_02565)	murB	544162..545040 (-)	879	WP_014973960.1	UDP-N-acetylmuramate dehydrogenase	-
FGL89_RS02570 (FGL89_02570)	ndk	545157..545570 (-)	414	WP_014973959.1	nucleoside-diphosphate kinase	-
FGL89_RS02575 (FGL89_02575)	-	545624..546139 (-)	516	WP_014973958.1	DUF1456 family protein	-
FGL89_RS02580 (FGL89_02580)	hexB	546206..548191 (-)	1986	WP_014973957.1	DNA mismatch repair endonuclease MutL	Machinery gene
FGL89_RS02585 (FGL89_02585)	hexA	548285..550879 (-)	2595	WP_014973956.1	DNA mismatch repair protein MutS	Machinery gene
FGL89_RS02590 (FGL89_02590)	recG/mmsA	550925..552955 (-)	2031	WP_135198074.1	ATP-dependent DNA helicase RecG	Machinery gene
FGL89_RS02595 (FGL89_02595)	-	553411..553935 (+)	525	WP_014973954.1	NADPH-dependent FMN reductase	-
FGL89_RS08720	-	554048..554188 (+)	141	WP_019040553.1	hypothetical protein	-
FGL89_RS08725	-	554201..554479 (+)	279	WP_014973953.1	ImmA/IrrE family metallo-endopeptidase	-
FGL89_RS02605 (FGL89_02605)	-	554544..555146 (+)	603	WP_014973952.1	DUF1643 domain-containing protein	-
FGL89_RS02610 (FGL89_02610)	-	555232..555507 (+)	276	WP_014973951.1	hypothetical protein	-
FGL89_RS08605	-	555591..555749 (+)	159	WP_014973950.1	hypothetical protein	-

Sequence

Protein

• Length: 864 a.a.
• Molecular weight: 96575.84 Da
• Isoelectric Point: 4.8491

>NTDB_id=331509 FGL89_RS02585 WP_014973956.1 548285..550879(-) (hexA) [Leuconostoc carnosum strain CBA3620]
MAKIVDTPMMVQYHEIKAQYPDAFVFYRLGDFYELFEDDAILGAKILELTLTARNKNSENPVPMAGIPHHAAQNYIDILV
DQGHKVAIVEQMEDPAVAKGMVKRDVVQLITPGTKMLGGAGADKENNYLAALRPNGNDLAMAYIDLSTGELKATTIGNFN
DVIDELSSLEVKEVVLRKDDELTIKHQVANQLGERGLVISWQSDVTANATVSFLTQPLTSIAETETTAMLLNYIFDTQRR
NLDHIVPATSYERLTYLKFNQDTRSNLDLIENTRTKKRAGSLLGLIDETKTAMGGRLLKQWLLKPLREQQEIEKRLDLVQ
AFQNDFFTRGALQDDLKSVYDLERLAARAAMGTMNARELVQLKKSLLAIPSIKTTLSATEGVLYDAGDKLDSMVDLAGLI
DEAIVDDPPVSVREGNIINDGFDEKIDTYRRVLTDNQKWLAQLETDERKVTGISSLKVGYNKNFGYFIEVTKANINKLEP
DRYERRQTLTNAERFVTPELKAHERLIIEAQAKRTEREYELFVTIRERLKANISRIQKLARLVARLDVLASLADVADNRR
FVRPTFTSHNMIAISQGRHPVVEALLGSGEFVANDVMLDEDNAMQLITGPNMAGKSTYMRELALIVILAQMGSFVPAEQA
ELPIFDQIFTRIGANDDIAMGQSTFMVEMAEANLALREATAHSLILFDELGRGTATYDGMALAQAIIEFLDAHIHAKTLF
STHYHELTALADRHDSITNVHVGAVEDDNGELHFLHQIQEGPADKSYGIHVAALAGLPRELINNATTILSHLESDDVVTD
HQLVQQSVTSEKHDESQQVELFNVDAVDSETEKVLEHLDKLDILNMTPVDAMNALNDLKKLRKK

Nucleotide

• Length: 2595 bp

>NTDB_id=331509 FGL89_RS02585 WP_014973956.1 548285..550879(-) (hexA) [Leuconostoc carnosum strain CBA3620]
ATGGCCAAAATAGTAGACACACCAATGATGGTGCAATATCATGAAATTAAGGCACAATACCCTGATGCATTTGTTTTTTA
TCGTTTAGGTGATTTTTATGAACTTTTTGAAGATGATGCGATATTAGGGGCTAAAATACTTGAATTAACACTGACAGCAC
GTAATAAAAATTCAGAAAACCCCGTGCCAATGGCGGGTATACCGCATCATGCTGCGCAAAATTATATTGATATTTTAGTA
GATCAAGGTCATAAAGTTGCTATTGTTGAGCAAATGGAAGATCCTGCCGTTGCTAAGGGTATGGTGAAGCGAGATGTTGT
TCAGCTGATTACGCCAGGCACAAAAATGCTTGGCGGTGCGGGTGCTGATAAAGAAAACAACTATCTAGCTGCTCTTAGAC
CAAACGGTAATGATTTGGCAATGGCTTATATTGATCTATCTACAGGCGAATTAAAAGCAACAACTATCGGTAACTTTAAT
GATGTGATTGATGAATTAAGTTCGTTGGAAGTTAAAGAAGTTGTGTTACGTAAAGATGACGAGCTTACCATAAAACATCA
AGTTGCTAATCAACTTGGGGAACGTGGTCTAGTAATTTCTTGGCAGTCAGATGTGACAGCAAATGCAACAGTTAGTTTTT
TGACACAACCCTTAACAAGCATTGCTGAAACTGAAACGACAGCAATGTTACTTAATTATATTTTTGATACGCAGCGCCGT
AATTTGGATCACATTGTGCCTGCTACGAGTTATGAGCGACTAACTTATTTGAAATTTAACCAAGACACACGTTCTAATTT
AGACTTAATTGAAAATACGCGTACGAAAAAACGTGCAGGTTCACTGCTAGGATTAATTGATGAGACGAAGACAGCTATGG
GTGGTCGGCTACTGAAACAGTGGCTACTAAAACCATTACGTGAGCAACAGGAGATTGAAAAGCGACTTGACTTGGTACAG
GCGTTTCAAAATGATTTTTTTACACGTGGTGCTTTGCAAGATGATTTGAAATCAGTATATGATTTGGAACGATTAGCAGC
TCGTGCGGCTATGGGTACGATGAATGCACGAGAACTTGTGCAACTCAAAAAATCATTATTAGCTATTCCAAGCATTAAAA
CCACTTTATCAGCAACAGAAGGAGTACTTTACGATGCTGGTGACAAGCTTGATAGCATGGTTGATTTGGCAGGGTTGATA
GATGAAGCTATTGTTGATGACCCACCGGTGAGTGTCCGTGAAGGTAATATTATTAACGACGGATTCGATGAAAAGATAGA
TACATATCGCAGAGTTTTGACTGACAATCAAAAATGGCTAGCCCAATTAGAAACTGATGAGCGTAAAGTTACCGGTATTA
GTTCATTGAAAGTCGGGTATAATAAAAATTTTGGTTATTTTATTGAAGTGACTAAAGCTAACATTAATAAATTAGAACCA
GATCGTTATGAGCGACGACAGACACTTACAAATGCAGAACGCTTTGTCACGCCAGAATTAAAAGCGCATGAACGTTTGAT
TATTGAGGCACAAGCTAAACGAACAGAAAGAGAATATGAATTATTTGTAACGATTCGTGAACGACTAAAGGCAAATATTA
GTCGTATTCAAAAGCTGGCAAGGTTAGTTGCGCGCTTGGATGTTTTAGCTTCACTAGCTGATGTCGCTGACAATCGCCGT
TTCGTACGTCCTACCTTTACTAGTCATAACATGATAGCCATATCTCAAGGAAGACATCCTGTGGTAGAAGCATTGCTCGG
TTCAGGTGAGTTTGTGGCAAATGATGTGATGTTAGATGAAGACAATGCCATGCAACTGATTACTGGTCCTAATATGGCTG
GAAAATCAACTTATATGCGTGAATTAGCCTTAATTGTTATCTTGGCACAAATGGGCAGTTTTGTACCAGCAGAACAAGCT
GAATTACCTATTTTTGATCAAATATTTACGCGAATTGGTGCTAATGATGATATTGCTATGGGACAGTCAACTTTTATGGT
TGAAATGGCAGAAGCTAACCTAGCTTTGCGAGAAGCAACAGCACATTCGCTTATTTTATTTGACGAATTAGGGCGTGGTA
CGGCAACTTATGACGGTATGGCACTGGCGCAAGCAATTATCGAATTTTTAGATGCGCATATTCATGCCAAAACACTGTTT
TCAACACATTATCATGAATTAACTGCATTAGCTGACCGGCATGATAGCATTACCAACGTTCATGTTGGTGCAGTAGAAGA
TGATAACGGGGAATTGCATTTTCTACATCAAATTCAAGAAGGACCAGCTGATAAATCTTATGGTATTCATGTTGCGGCAC
TGGCTGGCTTGCCACGCGAACTCATTAACAATGCTACGACCATTCTTTCTCATTTAGAAAGTGATGATGTCGTTACTGAT
CACCAGCTTGTCCAACAATCAGTGACGTCAGAAAAACATGACGAATCACAACAAGTTGAATTGTTCAATGTTGATGCTGT
TGATTCAGAGACAGAAAAAGTATTAGAACACTTAGATAAATTAGATATTTTAAACATGACACCTGTAGATGCCATGAATG
CACTAAATGACTTAAAAAAGTTAAGAAAAAAATAG

Domains

Predicted by InterProScan.

• MutS family domain IV (MutS_IV) (421-512)

• MutS domain I (MutS_I) (7-114)

• MutS domain III (MutS_III) (262-553)

• MutS domain II (MutS_II) (127-245)

• MutS domain V (MutS_V) (606-793)

3D structure

• AlphaFold DB: K0D978

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	47.368	98.958	0.469
mutS	Pseudomonas stutzeri strain ATCC 17587	38.844	100	0.389