Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   FGL89_RS02580 Genome accession   NZ_CP042374
Coordinates   546206..548191 (-) Length   661 a.a.
NCBI ID   WP_014973957.1    Uniprot ID   K0D647
Organism   Leuconostoc carnosum strain CBA3620     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 541206..553191
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGL89_RS02560 (FGL89_02560) - 542060..544156 (-) 2097 WP_014973961.1 Na+/H+ antiporter -
  FGL89_RS02565 (FGL89_02565) murB 544162..545040 (-) 879 WP_014973960.1 UDP-N-acetylmuramate dehydrogenase -
  FGL89_RS02570 (FGL89_02570) ndk 545157..545570 (-) 414 WP_014973959.1 nucleoside-diphosphate kinase -
  FGL89_RS02575 (FGL89_02575) - 545624..546139 (-) 516 WP_014973958.1 DUF1456 family protein -
  FGL89_RS02580 (FGL89_02580) hexB 546206..548191 (-) 1986 WP_014973957.1 DNA mismatch repair endonuclease MutL Machinery gene
  FGL89_RS02585 (FGL89_02585) hexA 548285..550879 (-) 2595 WP_014973956.1 DNA mismatch repair protein MutS Machinery gene
  FGL89_RS02590 (FGL89_02590) recG/mmsA 550925..552955 (-) 2031 WP_135198074.1 ATP-dependent DNA helicase RecG Machinery gene

Sequence

Protein


Download         Length: 661 a.a.        Molecular weight: 73626.24 Da        Isoelectric Point: 5.1666

>NTDB_id=331508 FGL89_RS02580 WP_014973957.1 546206..548191(-) (hexB) [Leuconostoc carnosum strain CBA3620]
MSKIHELSNLLANQIAAGEVIERPASVVKELVENAIDSGATQIDVVVENAGEALIRVVDNGTGIDPEDVPLAFTRHATSK
ITDRHDLFNVLSLGFRGEALPSIAAIADVTLNTTTIEAPAGVMYHIKGGNQVSSVPANGHRGTVISVRDLFYNTPARLKY
LKRPQTELSHIADIMNRLALSYTNIAFTVIADGRELLKTAGNGNQQQVIAAIYGRESAQKMLAIAGEDDDFNITGYISLP
ELTRGSREYLTILINGRFIKNFTISNAVIRGYGSKLMVGRFPMGVININTDPLLVDVNVHPQKSEVRLSKEVELSELIIG
SIKSRLAEENLIPDAYENLYGPSRAIQSTTSKPTQQAPWLEKSESKEQTVMPQNTINSGQEIEPISISDRHDLLNDQVND
FANRYAHESALSVFGQQSTVPQPQVSEDLVTYQAPRTKNQSQQEALDIAPNTASGFPALDYIGQMHGTFLFAQSETGLYL
IDQHAAQERIKYEYYRRVIGEVGTDKQRLLVPITLTYSAADMLKIADHEQELQAVGLELEPFGPTSVIIREHPTWFKAGQ
EKETVLEMVDWLLRAGHLTVAEFRERTAIMMSCKRSVRANMHLSEEQARTLLQSLAMTENPYNCPHGRPVLTQFTLTEME
KMFKRIQDSHENWEEYDNHPY

Nucleotide


Download         Length: 1986 bp        

>NTDB_id=331508 FGL89_RS02580 WP_014973957.1 546206..548191(-) (hexB) [Leuconostoc carnosum strain CBA3620]
ATGAGCAAAATTCATGAGCTATCAAATTTATTGGCTAACCAAATTGCGGCTGGTGAAGTTATTGAACGACCAGCCAGCGT
TGTTAAAGAATTAGTTGAAAATGCGATTGATTCAGGCGCAACACAAATTGACGTCGTCGTTGAGAATGCCGGCGAGGCGC
TTATTCGTGTTGTTGATAATGGTACAGGTATTGATCCTGAAGATGTCCCGCTAGCTTTTACACGCCACGCAACAAGCAAA
ATAACAGATCGTCATGATTTGTTTAATGTTCTGTCTTTAGGTTTTCGTGGTGAAGCATTACCATCGATTGCAGCAATTGC
CGACGTTACTTTAAATACGACAACTATTGAGGCACCAGCCGGTGTCATGTATCACATTAAAGGTGGCAATCAAGTCAGTT
CAGTGCCAGCTAATGGGCATCGTGGAACTGTGATTTCGGTACGCGATTTATTTTATAATACACCGGCACGATTGAAATAT
TTAAAGCGACCACAAACAGAGTTATCACATATTGCTGACATTATGAATCGGTTGGCACTGTCATATACAAACATTGCTTT
CACTGTCATTGCTGATGGGCGTGAATTACTAAAAACAGCAGGAAACGGTAACCAGCAACAAGTTATTGCGGCTATTTATG
GTCGTGAAAGTGCGCAAAAAATGCTAGCAATTGCTGGTGAAGACGACGATTTTAATATTACTGGCTATATATCTTTACCA
GAGCTAACACGTGGTTCACGAGAATATTTGACCATTTTAATTAATGGCCGTTTTATTAAAAACTTTACTATCTCTAATGC
TGTGATACGTGGTTACGGTTCAAAATTAATGGTTGGTCGGTTCCCAATGGGCGTGATTAACATTAATACCGATCCTCTTT
TGGTCGATGTGAATGTACATCCCCAAAAATCAGAAGTTCGCCTATCTAAGGAAGTTGAGTTATCTGAATTAATTATCGGT
AGTATCAAGTCGCGTTTAGCGGAAGAAAATTTAATACCTGATGCTTATGAAAATTTGTATGGCCCATCAAGAGCAATACA
ATCGACCACGTCAAAACCCACCCAGCAGGCGCCTTGGTTAGAAAAAAGTGAGTCCAAAGAACAAACAGTGATGCCACAAA
ACACTATTAATTCGGGTCAAGAGATTGAACCTATTAGTATCAGTGATCGACATGATTTATTAAATGATCAAGTTAATGAT
TTCGCTAATCGGTATGCTCATGAGTCTGCATTATCAGTTTTTGGGCAACAATCAACAGTGCCTCAACCTCAAGTATCTGA
GGATCTTGTAACATACCAAGCGCCACGGACGAAAAATCAATCACAACAAGAGGCACTTGATATCGCACCAAACACAGCTA
GTGGTTTTCCAGCATTGGACTATATTGGTCAAATGCATGGGACATTTTTGTTTGCACAAAGTGAAACAGGCTTATACTTA
ATCGATCAGCATGCTGCACAAGAGCGAATTAAATATGAGTACTATAGGCGTGTTATAGGCGAAGTAGGAACTGACAAACA
ACGGTTGTTGGTTCCAATCACGTTGACCTACTCGGCAGCTGATATGTTAAAAATTGCTGATCATGAACAAGAATTACAAG
CTGTTGGGTTAGAACTAGAGCCTTTTGGACCAACGAGTGTGATCATACGTGAACACCCAACATGGTTTAAAGCTGGTCAA
GAAAAGGAAACAGTATTAGAAATGGTTGATTGGCTTCTAAGGGCTGGACATCTCACGGTAGCTGAATTTCGTGAACGCAC
AGCCATCATGATGAGTTGTAAAAGGTCAGTTCGAGCCAATATGCATTTGTCTGAAGAACAAGCACGAACTTTATTACAAT
CACTTGCTATGACTGAAAATCCTTATAATTGCCCTCATGGACGCCCAGTATTAACACAGTTTACACTAACAGAAATGGAA
AAAATGTTTAAACGTATTCAAGACTCTCATGAAAATTGGGAAGAATATGATAATCATCCGTACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

MutL C terminal dimerisation domain (MutL_C)

(460-603)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-84)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB K0D647

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

46.726

100

0.475