Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FS836_RS10110 Genome accession   NZ_CP042352
Coordinates   2011398..2012054 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain RM9513     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2006398..2017054
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FS836_RS10080 (FS836_10155) yecA 2007649..2008314 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  FS836_RS10100 (FS836_10175) pgsA 2008964..2009512 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FS836_RS10105 (FS836_10180) uvrC 2009569..2011401 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FS836_RS10110 (FS836_10185) letA 2011398..2012054 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FS836_RS22600 - 2012196..2012267 (+) 72 Protein_1887 transcriptional regulator -
  FS836_RS10115 (FS836_10190) yecU 2012350..2012526 (+) 177 WP_000590347.1 protein YecU -
  FS836_RS10120 (FS836_10195) yecF 2012513..2012737 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FS836_RS10125 (FS836_10200) sdiA 2012804..2013526 (-) 723 WP_001154276.1 transcriptional regulator SdiA -
  FS836_RS10130 (FS836_10205) tcyN 2013756..2014508 (-) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FS836_RS10135 (FS836_10210) tcyL 2014505..2015173 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FS836_RS10140 (FS836_10215) dcyD 2015188..2016174 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=331432 FS836_RS10110 WP_000611335.1 2011398..2012054(-) (letA) [Escherichia coli strain RM9513]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=331432 FS836_RS10110 WP_000611335.1 2011398..2012054(-) (letA) [Escherichia coli strain RM9513]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486