Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   EJF26_RS09030 Genome accession   NZ_CP034442
Coordinates   1770543..1771232 (+) Length   229 a.a.
NCBI ID   WP_000518003.1    Uniprot ID   F9NZ56
Organism   Streptococcus oralis subsp. dentisani strain F0392     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1765543..1776232
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJF26_RS09005 gpsB 1765597..1765926 (+) 330 WP_000146526.1 cell division regulator GpsB -
  EJF26_RS09015 - 1766413..1767570 (+) 1158 WP_000711364.1 class I SAM-dependent RNA methyltransferase -
  EJF26_RS09020 - 1767583..1769031 (+) 1449 WP_000039118.1 cell division site-positioning protein MapZ family protein -
  EJF26_RS09025 gndA 1769107..1770531 (+) 1425 WP_000158801.1 NADP-dependent phosphogluconate dehydrogenase -
  EJF26_RS09030 covR 1770543..1771232 (+) 690 WP_000518003.1 response regulator transcription factor Regulator
  EJF26_RS09035 - 1771331..1772311 (+) 981 WP_000670350.1 N-acetylmuramoyl-L-alanine amidase family protein -
  EJF26_RS09040 mvk 1772431..1773309 (+) 879 WP_000163310.1 mevalonate kinase -
  EJF26_RS09045 mvaD 1773291..1774244 (+) 954 WP_000373464.1 diphosphomevalonate decarboxylase -
  EJF26_RS09050 - 1774231..1775238 (+) 1008 WP_000562386.1 phosphomevalonate kinase -
  EJF26_RS09055 fni 1775222..1776223 (+) 1002 WP_000210643.1 type 2 isopentenyl-diphosphate Delta-isomerase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26839.06 Da        Isoelectric Point: 8.0271

>NTDB_id=331399 EJF26_RS09030 WP_000518003.1 1770543..1771232(+) (covR) [Streptococcus oralis subsp. dentisani strain F0392]
MGKRILLLEKERNLAHFLSLELQKEQYRVDLVEEGQKALSMALQTDYDLILLNARLGDMTAQDFAERLSRIKPASVIMVL
DHREELQDQIETIQRFAVSYIYKPVIIDQLVARISAIFRGRDFIDQHCSQMKVPTSYRNLRMDVEHHTVYRGEEMIALTR
REYDLLATLMGSKKVLTREQLLESVWKYESATETNIVDVYIRYLRSKLDVKGQKSYIKTVRGVGYTMQE

Nucleotide


Download         Length: 690 bp        

>NTDB_id=331399 EJF26_RS09030 WP_000518003.1 1770543..1771232(+) (covR) [Streptococcus oralis subsp. dentisani strain F0392]
ATGGGGAAACGGATTTTATTACTTGAGAAAGAACGAAATCTCGCTCATTTTCTCAGTCTGGAACTCCAAAAAGAGCAATA
CCGTGTTGATCTGGTTGAGGAGGGGCAAAAAGCTCTCTCCATGGCTCTCCAGACAGATTATGACTTGATTTTACTGAATG
CTCGTCTGGGGGATATGACGGCCCAGGATTTTGCAGAGAGGCTGAGTCGGATAAAACCTGCCTCAGTGATCATGGTCTTG
GACCATCGCGAAGAATTGCAAGACCAGATTGAGACAATCCAGCGCTTCGCCGTTTCTTACATCTATAAGCCAGTGATTAT
TGATCAGCTGGTGGCTCGTATTTCAGCGATTTTCCGAGGTCGGGACTTTATCGACCAACACTGTAGTCAGATGAAGGTCC
CAACGTCTTACCGCAATCTGCGTATGGATGTAGAACATCATACCGTTTATCGTGGCGAGGAGATGATTGCTCTGACGCGC
CGTGAGTATGACCTTTTGGCCACTCTCATGGGAAGCAAGAAGGTCTTGACTCGTGAGCAGTTGTTGGAAAGTGTTTGGAA
GTACGAAAGTGCGACAGAAACCAATATCGTGGATGTTTATATCCGTTATCTACGTAGCAAGCTTGATGTAAAAGGTCAAA
AAAGCTACATTAAAACAGTGCGTGGTGTTGGTTACACCATGCAAGAATAG

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB F9NZ56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

49.13

100

0.493
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.93

99.563

0.467

Multiple sequence alignment