Detailed information NTG0331357

Bioinformatically predicted

Overview

• Name: sepM
• Type: Regulator
• Locus tag: EJF26_RS05880
• Genome accession: NZ_CP034442
• Coordinates: 1172346..1173383 (-)
• Length: 345 a.a.
• NCBI ID: WP_000730768.1
• Uniprot ID: A0A428EDP9
• Organism: Streptococcus oralis subsp. dentisani strain F0392
• Function: processing of CSP (predicted from homology) Competence regulation

Genomic Context

Location: 1167346..1178383

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EJF26_RS05855	-	1168244..1169575 (-)	1332	WP_000390012.1	hemolysin family protein	-
EJF26_RS05860	endA	1169715..1170539 (-)	825	WP_001036792.1	DNA/RNA non-specific endonuclease	Machinery gene
EJF26_RS05865	-	1170576..1170767 (-)	192	WP_000791880.1	DNA-directed RNA polymerase subunit beta	-
EJF26_RS05870	murA	1170757..1172037 (-)	1281	WP_000411896.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
EJF26_RS05875	-	1172060..1172290 (-)	231	WP_080563327.1	DUF1146 family protein	-
EJF26_RS05880	sepM	1172346..1173383 (-)	1038	WP_000730768.1	SepM family pheromone-processing serine protease	Regulator
EJF26_RS05885	coaD	1173367..1173855 (-)	489	WP_001280709.1	pantetheine-phosphate adenylyltransferase	-
EJF26_RS05890	rsmD	1173845..1174384 (-)	540	WP_000706947.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
EJF26_RS05895	asnA	1174449..1175441 (-)	993	WP_000747987.1	aspartate--ammonia ligase	-
EJF26_RS05900	-	1175550..1176233 (-)	684	WP_001076875.1	Bax inhibitor-1/YccA family protein	-
EJF26_RS05905	-	1176288..1177028 (-)	741	WP_004246533.1	RNA methyltransferase	-
EJF26_RS05910	-	1177062..1177340 (+)	279	WP_001174620.1	acylphosphatase	-
EJF26_RS05915	yidC	1177418..1178338 (+)	921	WP_025168371.1	membrane protein insertase YidC	-

Sequence

Protein

• Length: 345 a.a.
• Molecular weight: 37549.74 Da
• Isoelectric Point: 5.2751

>NTDB_id=331357 EJF26_RS05880 WP_000730768.1 1172346..1173383(-) (sepM) [Streptococcus oralis subsp. dentisani strain F0392]
MKKKTRWPLYVILALVLTFLAFVVPLPYYIEVPGGAEDIRQVLKVNETEDTEAGAYQFVTVGIRHATLSHLVYAWLTPFT
DIRSAQETTGGSTDAEFMRINQFYMQTSQNMAKYQGLKTAGKDIELKYLGVYVLTVTDNSTFKGILNIADTVTAVNDKTF
DSSKDLIDYVNSQKLGDPVKVTYEEDGRVKTAEGKIITLENGKNGIGIGLIDRTEVTSDVPIRFSTAGIGGPSAGLMFSL
AIYTQIADPGLRNGRIVAGTGTIDRDGNVGDIGGIDKKVVAASRQGANVFFAPDNPVTEEAKKADPNAKSNYETALEAAK
TIKTEMKIVPVKTLQDAIDYLKNNP

Nucleotide

• Length: 1038 bp

>NTDB_id=331357 EJF26_RS05880 WP_000730768.1 1172346..1173383(-) (sepM) [Streptococcus oralis subsp. dentisani strain F0392]
ATGAAGAAAAAAACTAGATGGCCCTTATATGTCATCCTAGCACTAGTATTGACTTTTTTAGCCTTTGTAGTACCTTTACC
TTATTACATAGAAGTTCCAGGTGGAGCGGAAGATATTCGTCAAGTTTTGAAAGTCAATGAAACAGAAGATACAGAAGCAG
GAGCTTACCAGTTTGTGACAGTCGGTATTCGACATGCAACCCTGTCTCATCTGGTCTATGCTTGGCTGACTCCATTTACG
GATATTAGAAGCGCTCAGGAGACAACGGGTGGCTCTACAGATGCAGAGTTTATGCGGATCAATCAGTTCTACATGCAAAC
ATCCCAAAATATGGCCAAGTATCAAGGCTTGAAGACGGCAGGCAAGGATATCGAACTCAAGTACTTGGGAGTTTATGTCT
TGACCGTGACGGACAATTCAACCTTTAAAGGCATTCTGAACATTGCGGATACCGTCACGGCTGTTAATGACAAAACATTT
GACAGTTCCAAAGACTTGATTGATTATGTCAACTCTCAAAAACTAGGAGATCCAGTCAAGGTAACCTACGAAGAAGACGG
AAGAGTCAAGACTGCTGAAGGTAAAATTATCACTCTCGAAAACGGGAAAAATGGGATTGGGATTGGCTTGATTGACCGTA
CGGAAGTGACCAGTGATGTTCCCATTCGCTTTTCAACAGCTGGTATCGGTGGCCCCAGTGCAGGTCTTATGTTTAGTCTC
GCTATTTACACCCAGATAGCAGATCCAGGACTTCGTAATGGTCGCATCGTTGCGGGAACGGGAACCATTGATCGCGATGG
AAATGTTGGCGACATCGGTGGAATTGACAAAAAAGTGGTTGCAGCCTCTCGTCAGGGAGCCAATGTCTTTTTTGCTCCTG
ACAATCCAGTCACCGAGGAAGCAAAAAAAGCAGATCCCAATGCGAAAAGCAACTATGAAACAGCCCTAGAAGCTGCTAAA
ACAATCAAGACAGAGATGAAAATTGTTCCCGTAAAAACCTTGCAGGATGCGATTGATTACCTCAAAAACAATCCCTAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (129-193)

• Lon protease (S16) C-terminal proteolytic domain (Lon_C) (230-296)

3D structure

• AlphaFold DB: A0A428EDP9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
sepM	Streptococcus mutans UA159	59.942	99.13	0.594