Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   EJN89_RS04425 Genome accession   NZ_CP034441
Coordinates   850896..851465 (-) Length   189 a.a.
NCBI ID   WP_000872877.1    Uniprot ID   A0A641A2F3
Organism   Staphylococcus aureus strain PMB 81-4     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 845896..856465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EJN89_RS04380 - 846370..846978 (-) 609 WP_000020302.1 class I SAM-dependent methyltransferase -
  EJN89_RS04385 rplL 847153..847521 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  EJN89_RS04390 rplJ 847564..848064 (-) 501 WP_001273087.1 50S ribosomal protein L10 -
  EJN89_RS04400 rplA 848336..849028 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  EJN89_RS04405 rplK 849236..849658 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  EJN89_RS04410 nusG 849839..850387 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  EJN89_RS04415 secE 850400..850582 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  EJN89_RS04420 rpmG 850638..850781 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  EJN89_RS04425 sigH 850896..851465 (-) 570 WP_000872877.1 RNA polymerase sigma factor Regulator
  EJN89_RS04430 - 851546..852070 (-) 525 WP_000664738.1 NYN domain-containing protein -
  EJN89_RS04435 rlmB 852070..852816 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  EJN89_RS04440 - 852824..853228 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  EJN89_RS04445 cysS 853221..854621 (-) 1401 WP_000631973.1 cysteine--tRNA ligase -
  EJN89_RS04450 cysE 854605..855252 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23126.01 Da        Isoelectric Point: 9.6015

>NTDB_id=331292 EJN89_RS04425 WP_000872877.1 850896..851465(-) (sigH) [Staphylococcus aureus strain PMB 81-4]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRYDVENNYLNKLAIKELIRQFKYLSVFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=331292 EJN89_RS04425 WP_000872877.1 850896..851465(-) (sigH) [Staphylococcus aureus strain PMB 81-4]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTATGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTCGTCAGTTTAAGTATTTGAGTGTATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAACTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641A2F3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus MW2

100

100

1
  sigH Staphylococcus aureus N315

97.884

100

0.979

Multiple sequence alignment