Detailed information NTG0033035

Bioinformatically predicted

Overview

• Name: vraS
• Type: Regulator
• Locus tag: SCA_RS07420
• Genome accession: NC_012121
• Coordinates: 1482607..1483650 (-)
• Length: 347 a.a.
• NCBI ID: WP_015900704.1
• Uniprot ID: A0AAJ0JP10
• Organism: Staphylococcus carnosus subsp. carnosus TM300
• Function: repress expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1477607..1488650

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCA_RS07390 (SCA_1453)	-	1478745..1478951 (-)	207	WP_015900698.1	DUF1128 family protein	-
SCA_RS07395 (SCA_1454)	-	1479187..1479651 (+)	465	WP_015900699.1	low molecular weight protein-tyrosine-phosphatase	-
SCA_RS07400 (SCA_1455)	-	1479659..1479955 (+)	297	WP_015900700.1	hypothetical protein	-
SCA_RS07405 (SCA_1456)	-	1480074..1481150 (+)	1077	WP_015900701.1	YihY/virulence factor BrkB family protein	-
SCA_RS07410 (SCA_1457)	-	1481360..1481938 (+)	579	WP_015900702.1	beta-class carbonic anhydrase	-
SCA_RS07415 (SCA_1458)	vraR	1481988..1482617 (-)	630	WP_041612989.1	response regulator transcription factor	Regulator
SCA_RS07420 (SCA_1459)	vraS	1482607..1483650 (-)	1044	WP_015900704.1	sensor histidine kinase	Regulator
SCA_RS07425 (SCA_1460)	liaF	1483647..1484348 (-)	702	WP_015900705.1	cell wall-active antibiotics response protein LiaF	-
SCA_RS07430 (SCA_1461)	-	1484364..1484759 (-)	396	WP_015900706.1	hypothetical protein	-
SCA_RS07435 (SCA_1462)	map	1484893..1485660 (-)	768	WP_015900707.1	type I methionyl aminopeptidase	-
SCA_RS07440 (SCA_1463)	-	1485912..1486898 (+)	987	WP_015900708.1	FUSC family protein	-
SCA_RS07445 (SCA_1464)	-	1486948..1487673 (-)	726	WP_015900709.1	type 1 glutamine amidotransferase	-

Sequence

Protein

• Length: 347 a.a.
• Molecular weight: 40122.55 Da
• Isoelectric Point: 5.1667

>NTDB_id=33035 SCA_RS07420 WP_015900704.1 1482607..1483650(-) (vraS) [Staphylococcus carnosus subsp. carnosus TM300]
MNHYIRAIGSMLILIYSILAIFFFIDKVFVNIIFFQGMFYTQIFGIPVFLFLNIIVILMSIIVGSVLAYKVNQQNHWIKD
QIEHSIEGEVVGINDQHIELYQETLDIYHMLVPLNQELHRLRIKTQDLTNETYNLNDTKVKKIIEDERQRLARELHDSVS
QQLFAASMMLSAIKETKLEPPLDQQIPTLEKMIQDSQLEMRALLLHLRPLGLKDRSLGEGIKDLVVDLQKKVPMKVVYDI
EDFEVPKGIEDHLFRITQEGISNTLRHAEGSKLTIDLYNKDDYLLLRIQDDGKGFDVDEKMEKSYGLKNMRERALEIGAT
LHIVSLPGAGTRIEVKAPLNKEEFDDD

Nucleotide

• Length: 1044 bp

>NTDB_id=33035 SCA_RS07420 WP_015900704.1 1482607..1483650(-) (vraS) [Staphylococcus carnosus subsp. carnosus TM300]
ATGAACCATTATATAAGAGCTATAGGTTCAATGTTAATACTGATTTACAGTATTTTAGCCATATTCTTTTTCATTGATAA
AGTCTTTGTAAATATTATCTTTTTTCAAGGAATGTTCTATACACAAATTTTTGGGATTCCGGTATTTTTGTTTTTAAATA
TCATTGTGATACTTATGTCTATTATCGTAGGTTCTGTTTTAGCATATAAGGTCAACCAGCAAAACCACTGGATTAAAGAT
CAAATTGAACATTCAATTGAAGGTGAAGTAGTTGGAATAAATGATCAACATATCGAACTTTATCAAGAAACACTCGATAT
TTACCATATGCTAGTACCTTTAAACCAAGAATTACATCGCTTACGTATCAAGACACAAGATTTAACGAATGAAACTTATA
ATTTGAATGATACAAAAGTGAAGAAAATTATAGAAGATGAACGTCAGCGTTTGGCCAGAGAATTGCATGACTCAGTCAGT
CAGCAATTATTTGCTGCGAGTATGATGTTATCTGCTATTAAAGAAACGAAGTTAGAACCGCCTTTAGATCAGCAAATTCC
AACACTTGAAAAAATGATTCAAGATTCACAACTTGAAATGCGTGCTTTATTACTCCATTTGCGTCCGTTAGGCTTGAAGG
ATCGCTCATTAGGAGAAGGTATTAAAGACTTGGTTGTGGACTTGCAGAAAAAAGTGCCGATGAAAGTAGTATATGACATC
GAAGATTTTGAAGTACCAAAAGGGATTGAAGATCATTTATTTCGTATTACCCAAGAAGGTATTTCAAATACGCTAAGACA
TGCTGAAGGTTCAAAATTAACAATAGATTTATATAATAAAGACGATTACTTACTTTTACGTATTCAAGATGATGGTAAAG
GTTTTGATGTAGATGAAAAAATGGAAAAAAGTTATGGATTAAAAAATATGCGAGAACGCGCATTAGAAATCGGAGCAACA
CTGCATATTGTATCATTGCCTGGTGCAGGGACAAGAATTGAAGTGAAAGCGCCGTTGAACAAGGAGGAATTCGATGACGA
TTAA

Domains

Predicted by InterproScan.

• Histidine kinase (HisKA_3) (147-210)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (249-340)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
vraS	Staphylococcus aureus N315	84.726	100	0.847