Detailed information    

insolico Bioinformatically predicted

Overview

Name   coiA   Type   Machinery gene
Locus tag   EFD74_RS04610 Genome accession   NZ_CP034259
Coordinates   962498..963484 (+) Length   328 a.a.
NCBI ID   WP_000959282.1    Uniprot ID   A0A7U7EXT8
Organism   Staphylococcus aureus strain P1D12C1     
Function   require for natural transformation (predicted from homology)   
Unclear

Genomic Context

Location: 957498..968484
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EFD74_RS04585 (EFD74_04800) opp4B 957712..958674 (+) 963 WP_000915997.1 oligopeptide ABC transporter permease -
  EFD74_RS04590 (EFD74_04805) opp4C 958686..959567 (+) 882 WP_001180280.1 oligopeptide ABC transporter permease -
  EFD74_RS04595 (EFD74_04810) trpS 959609..960598 (-) 990 WP_000448934.1 tryptophan--tRNA ligase -
  EFD74_RS04600 (EFD74_04815) spxA 960892..961287 (+) 396 WP_000258003.1 transcriptional regulator SpxA -
  EFD74_RS04605 (EFD74_04820) mecA 961658..962377 (+) 720 WP_001217728.1 adaptor protein MecA -
  EFD74_RS04610 (EFD74_04825) coiA 962498..963484 (+) 987 WP_000959282.1 competence protein CoiA Machinery gene
  EFD74_RS04615 (EFD74_04830) pepF 963532..965340 (+) 1809 WP_000082725.1 oligoendopeptidase F -
  EFD74_RS04620 (EFD74_04835) yjbH 965800..966606 (-) 807 WP_000896697.1 protease adaptor protein YjbH -
  EFD74_RS04625 (EFD74_04840) - 966629..966994 (-) 366 WP_156667995.1 truncated hemoglobin YjbI -
  EFD74_RS04630 (EFD74_04845) - 967098..967691 (-) 594 WP_000224619.1 CYTH domain-containing protein -
  EFD74_RS04635 (EFD74_04850) - 967877..968224 (+) 348 WP_001242103.1 hypothetical protein -

Sequence

Protein


Download         Length: 328 a.a.        Molecular weight: 38878.55 Da        Isoelectric Point: 9.5714

>NTDB_id=330284 EFD74_RS04610 WP_000959282.1 962498..963484(+) (coiA) [Staphylococcus aureus strain P1D12C1]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide


Download         Length: 987 bp        

>NTDB_id=330284 EFD74_RS04610 WP_000959282.1 962498..963484(+) (coiA) [Staphylococcus aureus strain P1D12C1]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

Competence protein CoiA-like family (CoiA_nuc)

(6-308)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7U7EXT8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  coiA Staphylococcus aureus N315

100

100

1
  coiA Staphylococcus aureus MW2

97.561

100

0.976

Multiple sequence alignment