Detailed information NTG0033025

Bioinformatically predicted

Overview

• Name: comGA
• Type: Machinery gene
• Locus tag: SCA_RS05845
• Genome accession: NC_012121
• Coordinates: 1181074..1182048 (-)
• Length: 324 a.a.
• NCBI ID: WP_015900415.1
• Uniprot ID: B9DNP2
• Organism: Staphylococcus carnosus subsp. carnosus TM300
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1176074..1187048

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCA_RS05810 (SCA_1161)	gcvT	1176565..1177659 (-)	1095	WP_015900410.1	glycine cleavage system aminomethyltransferase GcvT	-
SCA_RS05815 (SCA_1162)	-	1177850..1178389 (-)	540	WP_015900411.1	shikimate kinase	-
SCA_RS05820	comGF	1178560..1179018 (-)	459	WP_158297486.1	competence type IV pilus minor pilin ComGF	-
SCA_RS12835	-	1178975..1179271 (-)	297	WP_041612977.1	hypothetical protein	-
SCA_RS05830 (SCA_1163)	-	1179252..1179665 (-)	414	WP_231635362.1	prepilin-type cleavage/methylation domain-containing protein	-
SCA_RS05835 (SCA_1164)	comGC	1179685..1180011 (-)	327	WP_015900413.1	competence type IV pilus major pilin ComGC	Machinery gene
SCA_RS05840 (SCA_1165)	comGB	1180029..1181102 (-)	1074	WP_015900414.1	competence type IV pilus assembly protein ComGB	-
SCA_RS05845 (SCA_1166)	comGA	1181074..1182048 (-)	975	WP_015900415.1	competence type IV pilus ATPase ComGA	Machinery gene
SCA_RS05850 (SCA_1167)	-	1182119..1182742 (-)	624	WP_015900416.1	MBL fold metallo-hydrolase	-
SCA_RS05855 (SCA_1168)	-	1182742..1183071 (-)	330	WP_015900417.1	MTH1187 family thiamine-binding protein	-
SCA_RS05860 (SCA_1169)	-	1183071..1184057 (-)	987	WP_015900418.1	ROK family glucokinase	-
SCA_RS05865 (SCA_1170)	-	1184057..1184257 (-)	201	WP_015900419.1	YqgQ family protein	-
SCA_RS05870 (SCA_1171)	-	1184238..1185698 (-)	1461	WP_015900420.1	rhomboid family protein	-
SCA_RS05875 (SCA_1172)	-	1185715..1186257 (-)	543	WP_015900421.1	5-formyltetrahydrofolate cyclo-ligase	-

Sequence

Protein

• Length: 324 a.a.
• Molecular weight: 36963.71 Da
• Isoelectric Point: 7.1254

>NTDB_id=33025 SCA_RS05845 WP_015900415.1 1181074..1182048(-) (comGA) [Staphylococcus carnosus subsp. carnosus TM300]
MKRLLDTILTDAISKNVSDIHFIPIEKEVIIKFRIHDDLINYDNIEILTYSKLLTFMKFQAGLDVSNYHQAQSGQTTFKH
QKLYNLRVSTLPLSLGIESCVIRLSPQYFYQDTDRDGPKHFYHLMNKKQGLILFTGPTGSGKSTMMYEMVSFALKNLHLN
IITVEDPVEKRIAGITQISVNEKAGIDYENSFKAILRCDPDIILIGEIRDAQIAKCVIQASLSGHLVLSTLHSNDCEGAL
LRLLEMGISPQEAQQSIALISNQRLVTNQHGSRELAYETMYQSDIQYFFKHNHTMPKHFMKLSKVLTQMSEEGVICEEVL
KKYT

Nucleotide

• Length: 975 bp

>NTDB_id=33025 SCA_RS05845 WP_015900415.1 1181074..1182048(-) (comGA) [Staphylococcus carnosus subsp. carnosus TM300]
ATGAAAAGACTTTTAGATACAATTCTCACAGATGCAATTTCGAAAAATGTATCTGATATCCATTTTATTCCAATTGAAAA
AGAAGTTATAATCAAGTTCAGAATTCACGATGATTTAATTAATTATGACAATATCGAAATTCTGACTTATTCAAAGTTAC
TTACGTTTATGAAATTTCAAGCAGGGCTCGATGTATCTAATTATCATCAAGCACAAAGTGGTCAGACAACTTTCAAGCAT
CAAAAACTATATAATTTACGTGTTTCTACTTTACCGTTATCCTTAGGGATTGAGAGTTGTGTAATACGACTTTCACCCCA
GTATTTTTATCAAGATACCGATCGTGATGGTCCTAAACACTTCTATCATTTAATGAATAAAAAGCAAGGACTTATTTTAT
TCACGGGACCAACCGGTTCTGGAAAAAGTACTATGATGTATGAAATGGTTTCTTTTGCTTTAAAAAATTTGCATCTAAAT
ATTATTACTGTTGAAGACCCAGTTGAGAAAAGAATTGCTGGCATTACTCAAATTTCAGTAAATGAGAAAGCAGGTATAGA
TTATGAAAATTCATTTAAAGCTATATTACGCTGTGATCCCGATATTATACTTATTGGGGAGATAAGAGATGCTCAAATCG
CAAAATGTGTTATTCAAGCATCTCTAAGCGGACATCTAGTGCTTTCCACTTTGCATTCAAATGATTGCGAAGGAGCATTA
TTACGACTCTTGGAAATGGGTATATCTCCACAAGAAGCACAACAATCCATTGCTCTAATTTCAAATCAACGTCTAGTAAC
TAATCAACATGGAAGTAGAGAACTAGCTTATGAAACGATGTATCAATCTGATATTCAATACTTCTTCAAACATAACCATA
CAATGCCTAAACATTTTATGAAATTAAGCAAAGTACTAACTCAAATGAGTGAAGAAGGTGTTATATGTGAAGAAGTACTT
AAAAAATATACATAA

Domains

Predicted by InterproScan.

• Type II/IV secretion system protein (T2SSE) (8-267)

3D structure

• AlphaFold DB: B9DNP2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGA	Staphylococcus aureus MW2	60.681	99.691	0.605
comGA	Staphylococcus aureus N315	60.681	99.691	0.605