Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SUB_RS06920 Genome accession   NC_012004
Coordinates   1373212..1374513 (-) Length   433 a.a.
NCBI ID   WP_015911697.1    Uniprot ID   B9DV34
Organism   Streptococcus uberis 0140J     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1368212..1379513
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SUB_RS06910 (SUB1375) hpf 1371924..1372472 (-) 549 WP_015911695.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SUB_RS06915 (SUB1376) - 1372548..1373222 (-) 675 WP_015911696.1 ComF family protein -
  SUB_RS06920 (SUB1377) comFA/cflA 1373212..1374513 (-) 1302 WP_015911697.1 DEAD/DEAH box helicase Machinery gene
  SUB_RS06925 (SUB1378) - 1374570..1375199 (+) 630 WP_015911698.1 YigZ family protein -
  SUB_RS06930 (SUB1379) cysK 1375308..1376240 (+) 933 WP_015911699.1 cysteine synthase A -
  SUB_RS06935 (SUB1380) - 1376255..1376611 (-) 357 WP_015911700.1 S1 RNA-binding domain-containing protein -
  SUB_RS06940 (SUB1381) - 1376611..1378011 (-) 1401 WP_037593423.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SUB_RS06945 (SUB1382) - 1378045..1378686 (-) 642 WP_015911702.1 response regulator transcription factor -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 50066.38 Da        Isoelectric Point: 10.1114

>NTDB_id=32935 SUB_RS06920 WP_015911697.1 1373212..1374513(-) (comFA/cflA) [Streptococcus uberis 0140J]
MDELNAYDGRRFTPYQVPKQLLQYASVQDSMYKEGSKWFCGRCHMPVSNKNKLPNGHYYCRECIIFGRNESHSHLYTFPA
RPFPNTQALKWMGQLTPFQEKISRQLVSESKKKQKRLVHAVTGAGKTEMIYGLITSYLNEGKWVCIASPRIDVCIELYGR
LKNDFTCPITLMHGESEVYHKSPLIVATTHQLLKFYRAFDLMVIDEVDSFPFVGNSILSRAVTSALKEEGEILYLTATST
KELDLKVKRGDIEKLTLPRRFHNQPLIVPKFKLILNLEESLQKKRLPIPLLNMIRRQRKTNYPLLIFHPIIDKGEEFFRL
LATKLRNEKIAYVSSQSDHRKQIIEQFRKSEISILITTTILERGVTFPGVDVFVLLSHHKLFNASSLIQISGRVGRSLDR
PTGQLFFLHQGISIDMLKAKKEIIRMNREAYGQ

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=32935 SUB_RS06920 WP_015911697.1 1373212..1374513(-) (comFA/cflA) [Streptococcus uberis 0140J]
ATGGATGAATTAAATGCTTACGATGGCCGTCGCTTCACTCCTTACCAAGTTCCAAAACAGTTATTGCAGTATGCAAGTGT
TCAAGATAGTATGTACAAAGAGGGTTCTAAGTGGTTTTGTGGCAGATGTCATATGCCTGTTTCAAATAAAAACAAGTTAC
CTAATGGTCACTACTATTGTAGGGAATGTATTATTTTCGGTCGAAATGAGAGTCATTCTCACCTTTATACTTTTCCGGCT
AGGCCATTTCCTAACACTCAGGCTCTAAAGTGGATGGGACAATTAACACCATTTCAAGAAAAAATATCGCGTCAGCTTGT
CTCAGAATCAAAGAAAAAACAAAAGCGACTGGTGCATGCTGTTACTGGTGCAGGCAAAACGGAGATGATTTATGGATTAA
TAACCTCTTATCTTAATGAAGGAAAATGGGTTTGTATAGCTAGTCCGCGTATTGATGTTTGTATTGAACTGTACGGTCGC
TTAAAAAATGATTTTACCTGTCCAATTACGCTGATGCATGGAGAATCAGAAGTCTATCACAAAAGTCCCTTAATCGTTGC
TACGACGCATCAGTTGTTAAAGTTTTATCGGGCCTTTGATTTAATGGTTATTGATGAAGTTGATTCATTCCCTTTCGTTG
GGAATAGCATCTTGAGTCGGGCTGTTACTTCAGCTTTAAAAGAGGAGGGTGAAATCCTTTATCTTACGGCTACCTCGACT
AAAGAGCTTGATTTGAAAGTGAAAAGAGGTGATATTGAGAAACTAACATTACCTAGACGTTTCCATAATCAACCCTTGAT
TGTCCCTAAATTTAAACTTATCCTTAATTTGGAAGAATCATTACAAAAAAAGCGTCTCCCTATTCCGTTATTGAACATGA
TTCGAAGGCAAAGAAAAACAAATTACCCACTATTAATTTTTCATCCCATTATAGATAAGGGTGAGGAGTTTTTTCGTTTA
TTAGCAACTAAACTGAGGAATGAAAAGATTGCCTATGTCTCAAGTCAATCCGATCATAGAAAGCAGATAATTGAACAATT
TAGGAAATCAGAAATATCTATTTTAATCACGACAACAATCCTAGAAAGAGGCGTAACCTTTCCAGGTGTAGATGTGTTTG
TGCTTTTGTCTCATCACAAATTATTTAATGCGTCTAGCCTTATACAAATTTCGGGACGCGTTGGAAGATCTCTTGATCGC
CCAACGGGGCAGCTATTTTTCTTACATCAAGGAATTAGCATAGATATGTTAAAAGCCAAAAAAGAAATTATCAGGATGAA
TAGGGAGGCATATGGACAATAG

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(95-209)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB B9DV34

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae D39

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae R6

54.009

97.921

0.529
  comFA/cflA Streptococcus pneumoniae TIGR4

54.009

97.921

0.529
  comFA/cflA Streptococcus mitis NCTC 12261

53.538

97.921

0.524
  comFA/cflA Streptococcus mitis SK321

53.302

97.921

0.522
  comFA Lactococcus lactis subsp. cremoris KW2

49.62

91.224

0.453
  comFA Latilactobacillus sakei subsp. sakei 23K

37.615

100

0.379

Multiple sequence alignment