Detailed information NTG0032926

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: SUB_RS03935
• Genome accession: NC_012004
• Coordinates: 752256..753485 (+)
• Length: 409 a.a.
• NCBI ID: WP_012658290.1
• Uniprot ID: A0A2X4EFJ3
• Organism: Streptococcus uberis 0140J
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 747256..758485

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SUB_RS03915 (SUB0769)	-	747978..749264 (-)	1287	WP_041817579.1	hydroxymethylglutaryl-CoA reductase, degradative	-
SUB_RS03920 (SUB0770)	-	749251..750426 (-)	1176	WP_012658286.1	hydroxymethylglutaryl-CoA synthase	-
SUB_RS03925 (SUB0771)	-	750621..751460 (+)	840	WP_012658287.1	thymidylate synthase	-
SUB_RS03930 (SUB0772)	-	751540..752037 (+)	498	WP_012658288.1	dihydrofolate reductase	-
SUB_RS03935 (SUB0773)	clpX	752256..753485 (+)	1230	WP_012658290.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
SUB_RS03940 (SUB0774)	yihA	753496..754095 (+)	600	WP_012658291.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
SUB_RS03945 (SUB0775)	-	754248..754970 (+)	723	WP_012658292.1	hypothetical protein	-
SUB_RS03950 (SUB0776)	-	755040..757142 (-)	2103	WP_012658293.1	AAA family ATPase	-
SUB_RS03955 (SUB0777)	rplJ	757544..758044 (+)	501	WP_012658294.1	50S ribosomal protein L10	-
SUB_RS03960 (SUB0778)	rplL	758110..758475 (+)	366	WP_012658295.1	50S ribosomal protein L7/L12	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 45059.60 Da
• Isoelectric Point: 4.4892

>NTDB_id=32926 SUB_RS03935 WP_012658290.1 752256..753485(+) (clpX) [Streptococcus uberis 0140J]
MAGNRSTDIKVHCSFCGKSQDEVKKIIAGNNVFICNECVLLSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALAVAVYNHYKRISFSESRDEEEVELQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNSRKIDEDASYMQEIISDDIQKFGLIPEFIGRLPVVAALEQLNIDDLIQI
LTVPKNALVKQYQALLSYDGVELSFDQDALEAIAAKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVVKVRITKESVNG
DAKPILETA

Nucleotide

• Length: 1230 bp

>NTDB_id=32926 SUB_RS03935 WP_012658290.1 752256..753485(+) (clpX) [Streptococcus uberis 0140J]
ATGGCAGGAAATAGAAGTACTGATATTAAGGTACATTGTTCATTTTGTGGTAAAAGCCAAGATGAAGTTAAAAAAATAAT
CGCAGGTAATAATGTTTTTATCTGTAATGAATGTGTTCTTTTATCACAAGAAATTATTAAAGAAGAGTTAGCAGAAGAAG
TCTTAGCTGATTTAACAGAAGTTCCAAAACCAAAGGAACTTTTAGATGTTTTAAACCAATATGTAGTCGGTCAGGACCGT
GCTAAAAGAGCATTGGCTGTTGCGGTTTACAATCATTATAAACGCATTTCATTTTCTGAAAGTCGTGATGAAGAGGAAGT
TGAATTGCAAAAATCAAACATCTTGATGATTGGGCCAACAGGATCTGGTAAGACCTTCTTAGCCCAAACCTTGGCAAAAA
GTTTAAATGTGCCTTTTGCCATTGCTGATGCAACATCATTAACAGAAGCAGGCTATGTCGGAGAAGATGTTGAAAATATT
TTGTTGAAACTTATCCAAGCTGCTGATTACAATGTTGAACGAGCAGAACGTGGTATTATTTACGTAGACGAAATAGACAA
AATTGCCAAAAAAGGTGAGAATGTCTCTATCACACGTGATGTATCAGGAGAAGGAGTTCAACAAGCCTTGTTGAAAATCA
TTGAAGGGACAGTTGCATCTGTTCCACCTCAAGGAGGCCGGAAACACCCTAATCAAGAGATGATTCAAATTGATACCAAA
AATATTTTATTTATCGTTGGCGGTGCTTTTGATGGCATTGAAGAAATTGTCAAACAGCGATTGGGTGAAAAAATCATTGG
CTTTGGTCAAAATTCCCGTAAGATTGATGAAGATGCTTCTTATATGCAAGAAATCATTTCTGATGATATTCAAAAATTCG
GTCTTATACCAGAATTCATTGGTCGCCTACCAGTTGTAGCTGCTTTAGAACAGCTCAACATAGATGACCTCATTCAAATT
TTGACAGTTCCGAAAAATGCTTTGGTTAAACAATATCAAGCCCTATTGTCATATGATGGTGTTGAATTGTCATTTGATCA
AGATGCTTTAGAAGCTATTGCGGCGAAAGCTATTGAAAGAAAAACAGGTGCGCGTGGTTTACGTTCCATTATTGAAGAAA
CCATGTTAGATATTATGTTTGAAATTCCTAGTCAGGAAGATGTAGTCAAAGTACGTATTACCAAGGAATCTGTCAATGGT
GACGCAAAACCGATTTTAGAAACAGCGTAG

Domains

Predicted by InterproScan.

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-390)

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

3D structure

• AlphaFold DB: A0A2X4EFJ3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.264	100	0.883
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.603	98.044	0.575