Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   EH163_RS11480 Genome accession   NZ_CP034115
Coordinates   2305867..2306739 (-) Length   290 a.a.
NCBI ID   WP_002491388.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain CDC121     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 2301169..2338111 2305867..2306739 within 0


Gene organization within MGE regions


Location: 2301169..2338111
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EH163_RS11465 xerC 2301169..2302059 (-) 891 WP_058649777.1 tyrosine recombinase XerC -
  EH163_RS11470 trmFO 2302283..2303590 (-) 1308 WP_002473845.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  EH163_RS11475 topA 2303615..2305684 (-) 2070 WP_002446285.1 type I DNA topoisomerase -
  EH163_RS11480 dprA 2305867..2306739 (-) 873 WP_002491388.1 DNA-processing protein DprA Machinery gene
  EH163_RS13145 - 2307063..2307278 (-) 216 Protein_2130 transposase -
  EH163_RS11485 sucD 2307529..2308437 (-) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  EH163_RS11490 sucC 2308459..2309625 (-) 1167 WP_002439496.1 ADP-forming succinate--CoA ligase subunit beta -
  EH163_RS11495 - 2309733..2310503 (-) 771 WP_058649779.1 ribonuclease HII -
  EH163_RS11500 ylqF 2310508..2311371 (-) 864 WP_002491374.1 ribosome biogenesis GTPase YlqF -
  EH163_RS11510 - 2311699..2314299 (+) 2601 WP_058649780.1 YfhO family protein -
  EH163_RS11515 - 2314292..2316895 (+) 2604 WP_001832567.1 YfhO family protein -
  EH163_RS11520 rplS 2317426..2317776 (-) 351 WP_002436293.1 50S ribosomal protein L19 -
  EH163_RS11525 trmD 2317882..2318619 (-) 738 WP_001829466.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  EH163_RS11530 rimM 2318619..2319122 (-) 504 WP_058649781.1 ribosome maturation factor RimM -
  EH163_RS11535 rpsP 2319249..2319524 (-) 276 WP_002439483.1 30S ribosomal protein S16 -
  EH163_RS11540 ffh 2319770..2321137 (-) 1368 WP_001830113.1 signal recognition particle protein -
  EH163_RS11545 - 2321168..2321500 (-) 333 WP_001830102.1 putative DNA-binding protein -
  EH163_RS11550 ftsY 2321502..2322728 (-) 1227 WP_001830080.1 signal recognition particle-docking protein FtsY -
  EH163_RS11555 smc 2322725..2326294 (-) 3570 WP_001833035.1 chromosome segregation protein SMC -
  EH163_RS11560 rnc 2326421..2327158 (-) 738 WP_001830158.1 ribonuclease III -
  EH163_RS11565 - 2327273..2327506 (-) 234 WP_001830184.1 acyl carrier protein -
  EH163_RS11570 fabG 2327670..2328404 (-) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  EH163_RS11575 fabD 2328397..2329323 (-) 927 WP_058649783.1 ACP S-malonyltransferase -
  EH163_RS11580 plsX 2329325..2330302 (-) 978 WP_001830112.1 phosphate acyltransferase PlsX -
  EH163_RS11585 fapR 2330304..2330864 (-) 561 WP_001830099.1 transcription factor FapR -
  EH163_RS11590 recG 2331023..2333071 (-) 2049 WP_001830069.1 ATP-dependent DNA helicase RecG -
  EH163_RS11595 fakA 2333275..2334933 (-) 1659 WP_001830116.1 fatty acid kinase catalytic subunit FakA -
  EH163_RS11600 - 2334948..2335322 (-) 375 WP_001830156.1 Asp23/Gls24 family envelope stress response protein -
  EH163_RS11605 rpmB 2335680..2335868 (+) 189 WP_001830107.1 50S ribosomal protein L28 -
  EH163_RS11610 - 2335951..2336586 (-) 636 WP_001830164.1 thiamine diphosphokinase -
  EH163_RS11615 rpe 2336591..2337235 (-) 645 WP_001830173.1 ribulose-phosphate 3-epimerase -
  EH163_RS11620 rsgA 2337236..2338111 (-) 876 WP_001830137.1 ribosome small subunit-dependent GTPase A -

Sequence

Protein


Download         Length: 290 a.a.        Molecular weight: 33892.93 Da        Isoelectric Point: 9.7522

>NTDB_id=329171 EH163_RS11480 WP_002491388.1 2305867..2306739(-) (dprA) [Staphylococcus epidermidis strain CDC121]
MIQHTMLKLYWANFTTAQLHHLTRKYPDFLSENVFHQHDMIKRWLTERNSERLWNKYERFKKLKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYFLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPINKYKFPERNRLISGLSRGVFITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILIDYLF

Nucleotide


Download         Length: 873 bp        

>NTDB_id=329171 EH163_RS11480 WP_002491388.1 2305867..2306739(-) (dprA) [Staphylococcus epidermidis strain CDC121]
TTGATACAACATACGATGTTAAAACTATATTGGGCAAATTTCACTACAGCACAACTTCATCATCTTACACGTAAATATCC
CGACTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGATGGCTTACAGAGCGTAATTCTGAAAGACTAT
GGAACAAATATGAACGTTTCAAAAAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACG
ACATACTTCGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTCTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGTGGCGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACTTTTTACCAACTATTGGCGTACTTGGATTTGGACATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGAAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCTATAAATAAGTATAAATTTC
CTGAAAGAAACAGACTTATAAGTGGTCTGTCTAGAGGGGTTTTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATT
ACTATTGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGCAA
TTTACGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATCTTAATTGATTATCTATTTTAG

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

57.292

99.31

0.569
  dprA Staphylococcus aureus N315

57.292

99.31

0.569

Multiple sequence alignment