Detailed information
Bioinformatically predicted
Overview
| Name | comK/comK1 | Type | Regulator |
| Locus tag | EH162_RS00220 | Genome accession | NZ_CP034111 |
| Coordinates | 27102..27677 (-) | Length | 191 a.a. |
| NCBI ID | WP_001829272.1 | Uniprot ID | - |
| Organism | Staphylococcus epidermidis strain CDC120 | ||
| Function | promote expression of competence genes (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 596..26701 | 27102..27677 | flank | 401 |
Gene organization within MGE regions
Location: 596..27677
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EH162_RS00010 | - | 596..958 (-) | 363 | WP_002504164.1 | hypothetical protein | - |
| EH162_RS00015 | - | 1022..1207 (-) | 186 | WP_002456405.1 | hypothetical protein | - |
| EH162_RS00020 | - | 1226..1855 (-) | 630 | WP_049401376.1 | major tail protein | - |
| EH162_RS00025 | - | 1868..2272 (-) | 405 | WP_124726159.1 | hypothetical protein | - |
| EH162_RS00030 | - | 2277..2543 (-) | 267 | WP_124726160.1 | hypothetical protein | - |
| EH162_RS00035 | - | 2678..3007 (-) | 330 | WP_100481683.1 | head-tail adaptor protein | - |
| EH162_RS00040 | - | 2997..3338 (-) | 342 | WP_124726161.1 | head-tail connector protein | - |
| EH162_RS00045 | - | 3357..4697 (-) | 1341 | WP_124726162.1 | phage major capsid protein | - |
| EH162_RS00050 | - | 4738..5295 (-) | 558 | WP_103433950.1 | HK97 family phage prohead protease | - |
| EH162_RS00055 | - | 5285..6517 (-) | 1233 | WP_002456397.1 | phage portal protein | - |
| EH162_RS00060 | - | 6517..6711 (-) | 195 | WP_002500102.1 | hypothetical protein | - |
| EH162_RS00065 | - | 6723..8417 (-) | 1695 | WP_124726163.1 | terminase TerL endonuclease subunit | - |
| EH162_RS00070 | - | 8404..8871 (-) | 468 | WP_002500104.1 | phage terminase small subunit P27 family | - |
| EH162_RS00075 | - | 9043..9393 (-) | 351 | WP_124726230.1 | HNH endonuclease | - |
| EH162_RS00080 | - | 9870..10316 (-) | 447 | WP_002484732.1 | transcriptional regulator | - |
| EH162_RS00085 | - | 10333..10482 (-) | 150 | WP_002484731.1 | DUF1514 family protein | - |
| EH162_RS00090 | - | 10482..10649 (-) | 168 | WP_124726164.1 | regulator | - |
| EH162_RS00095 | - | 10754..11056 (+) | 303 | WP_124726165.1 | DUF4870 domain-containing protein | - |
| EH162_RS00100 | dut | 11147..11569 (-) | 423 | WP_049367129.1 | dUTP diphosphatase | - |
| EH162_RS00105 | - | 11626..11943 (+) | 318 | WP_237624469.1 | hypothetical protein | - |
| EH162_RS13190 | - | 12083..12430 (-) | 348 | WP_267953678.1 | hypothetical protein | - |
| EH162_RS00115 | - | 12431..12838 (-) | 408 | WP_124726166.1 | RusA family crossover junction endodeoxyribonuclease | - |
| EH162_RS00120 | - | 12878..13765 (-) | 888 | WP_124726167.1 | DnaD domain protein | - |
| EH162_RS00125 | ssbA | 13795..14268 (-) | 474 | WP_124726168.1 | single-stranded DNA-binding protein | Machinery gene |
| EH162_RS00130 | - | 14269..14886 (-) | 618 | WP_237624473.1 | MBL fold metallo-hydrolase | - |
| EH162_RS00135 | - | 14967..15887 (-) | 921 | WP_124726170.1 | recombinase RecT | - |
| EH162_RS00140 | - | 15889..17841 (-) | 1953 | WP_124726171.1 | ATPase | - |
| EH162_RS12745 | - | 17903..18079 (-) | 177 | WP_164493039.1 | hypothetical protein | - |
| EH162_RS00145 | - | 18167..18448 (+) | 282 | WP_124726172.1 | hypothetical protein | - |
| EH162_RS12750 | - | 18445..18591 (-) | 147 | WP_001830230.1 | hypothetical protein | - |
| EH162_RS00150 | - | 18605..18814 (-) | 210 | WP_001830281.1 | hypothetical protein | - |
| EH162_RS12755 | - | 18869..19045 (+) | 177 | WP_164493040.1 | hypothetical protein | - |
| EH162_RS00155 | - | 19207..19701 (-) | 495 | WP_124726173.1 | ORF6C domain-containing protein | - |
| EH162_RS00160 | - | 19791..20012 (-) | 222 | WP_124726174.1 | hypothetical protein | - |
| EH162_RS00165 | - | 20024..20905 (-) | 882 | WP_124726175.1 | DUF3102 domain-containing protein | - |
| EH162_RS00170 | - | 20951..21175 (+) | 225 | WP_032603797.1 | hypothetical protein | - |
| EH162_RS12760 | - | 21168..21308 (-) | 141 | WP_164493041.1 | hypothetical protein | - |
| EH162_RS00175 | - | 21325..21540 (-) | 216 | WP_124726176.1 | helix-turn-helix transcriptional regulator | - |
| EH162_RS00180 | - | 21739..22350 (+) | 612 | WP_124726177.1 | LexA family transcriptional regulator | - |
| EH162_RS12765 | - | 22395..22562 (+) | 168 | WP_164493042.1 | hypothetical protein | - |
| EH162_RS00185 | - | 22566..23723 (+) | 1158 | WP_164493043.1 | CapA family protein | - |
| EH162_RS00190 | - | 24046..24273 (+) | 228 | WP_237624471.1 | hypothetical protein | - |
| EH162_RS13195 | - | 24514..24750 (+) | 237 | WP_124726232.1 | hypothetical protein | - |
| EH162_RS00200 | - | 24775..25569 (+) | 795 | WP_124726179.1 | DUF1828 domain-containing protein | - |
| EH162_RS00205 | - | 25652..26701 (+) | 1050 | WP_002439151.1 | site-specific integrase | - |
| EH162_RS00220 | comK/comK1 | 27102..27677 (-) | 576 | WP_001829272.1 | competence protein ComK | Regulator |
Sequence
Protein
Download Length: 191 a.a. Molecular weight: 22782.87 Da Isoelectric Point: 9.2887
>NTDB_id=329103 EH162_RS00220 WP_001829272.1 27102..27677(-) (comK/comK1) [Staphylococcus epidermidis strain CDC120]
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
MTHLPETIYVIRKGDMVIRPKYDEYQQTNGTEIIRFDQTRKESPFKVQRIIERSCKFYGNNYISKKAETNRITGISSKPP
ILLTPLFPTYFFPTHSDRQEENIWINMHYIENVKELKNRKSKIIFANGDSLTLNVSFHSLWHQYTNAIIYYYMVDKQSRM
KSNNPEQPIDYNQSSLNIFEALSRYSLFEEN
Nucleotide
Download Length: 576 bp
>NTDB_id=329103 EH162_RS00220 WP_001829272.1 27102..27677(-) (comK/comK1) [Staphylococcus epidermidis strain CDC120]
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
ATGACACATTTACCCGAAACGATTTATGTTATACGAAAAGGTGATATGGTAATACGACCTAAATATGATGAATATCAGCA
AACAAATGGTACTGAAATTATCAGATTTGATCAAACTCGCAAAGAAAGTCCATTTAAAGTACAGAGAATTATCGAAAGAT
CATGTAAATTTTATGGTAATAATTATATTAGTAAAAAAGCAGAAACGAATCGTATTACTGGAATCTCTAGTAAACCACCT
ATTTTACTTACGCCTCTTTTTCCTACTTACTTTTTTCCAACTCACTCAGACCGTCAAGAAGAAAATATATGGATTAATAT
GCATTATATTGAAAATGTTAAAGAACTTAAAAATCGTAAGAGTAAAATAATTTTTGCGAATGGTGATTCGTTAACGCTCA
ATGTATCATTTCATAGCTTGTGGCATCAATATACGAATGCAATCATCTATTATTACATGGTAGATAAGCAATCACGAATG
AAATCTAACAACCCTGAACAACCCATTGACTATAATCAGTCTTCTCTAAATATTTTCGAGGCGCTCTCACGCTACTCCCT
TTTTGAAGAAAATTAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comK/comK1 | Staphylococcus aureus MW2 |
76.757 |
96.859 |
0.743 |
| comK/comK1 | Staphylococcus aureus N315 |
76.757 |
96.859 |
0.743 |