Detailed information NTG0328400

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EGH17_RS10060
• Genome accession: NZ_CP034030
• Coordinates: 1697650..1698510 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FQ02
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1692650..1703510

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGH17_RS10040 (EGH17_10040)	dapD	1693160..1693981 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
EGH17_RS10045 (EGH17_10045)	pgi	1694191..1695834 (-)	1644	WP_003689806.1	glucose-6-phosphate isomerase	-
EGH17_RS10055 (EGH17_10055)	pilG	1696344..1697576 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
EGH17_RS10060 (EGH17_10060)	pilD	1697650..1698510 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
EGH17_RS10065 (EGH17_10065)	coaE	1698507..1699139 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
EGH17_RS10070 (EGH17_10070)	-	1699132..1699341 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
EGH17_RS10075 (EGH17_10075)	pilF	1699427..1701103 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EGH17_RS10090 (EGH17_10090)	-	1701441..1701887 (-)	447	WP_003689818.1	DUF441 domain-containing protein	-
EGH17_RS10095 (EGH17_10095)	-	1701891..1702865 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
EGH17_RS10105 (EGH17_10105)	rplU	1703089..1703397 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=328400 EGH17_RS10060 WP_003689814.1 1697650..1698510(+) (pilD) [Neisseria gonorrhoeae strain FQ02]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=328400 EGH17_RS10060 WP_003689814.1 1697650..1698510(+) (pilD) [Neisseria gonorrhoeae strain FQ02]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441