Detailed information NTG0328366

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: FO444_RS12210
• Genome accession: NZ_CP041759
• Coordinates: 2391514..2394036 (-)
• Length: 840 a.a.
• NCBI ID: WP_098403553.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain IMAU11823
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2386514..2399036

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FO444_RS12190 (FO444_12145)	ruvB	2386771..2387772 (-)	1002	WP_003131994.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
FO444_RS12195 (FO444_12150)	ruvA	2387899..2388492 (-)	594	WP_017865241.1	Holliday junction branch migration protein RuvA	Machinery gene
FO444_RS12200 (FO444_12155)	hexB	2388605..2390575 (-)	1971	WP_026138979.1	DNA mismatch repair endonuclease MutL	Machinery gene
FO444_RS12205 (FO444_12160)	-	2390704..2391399 (-)	696	WP_017865243.1	hypothetical protein	-
FO444_RS12210 (FO444_12165)	hexA	2391514..2394036 (-)	2523	WP_098403553.1	DNA mismatch repair protein MutS	Machinery gene
FO444_RS12215 (FO444_12170)	-	2394229..2394576 (-)	348	WP_012898702.1	RicAFT regulatory complex protein RicA family protein	-
FO444_RS12220 (FO444_12175)	-	2394793..2395674 (-)	882	WP_003132001.1	NAD(P)-dependent oxidoreductase	-
FO444_RS12225	-	2395716..2395922 (-)	207	WP_211752759.1	hypothetical protein	-
FO444_RS12235 (FO444_12190)	-	2396217..2396594 (-)	378	WP_017865245.1	DUF1634 domain-containing protein	-
FO444_RS12240 (FO444_12195)	-	2396594..2397445 (-)	852	WP_010906392.1	sulfite exporter TauE/SafE family protein	-
FO444_RS12245 (FO444_12200)	-	2397631..2397810 (+)	180	WP_003132007.1	hypothetical protein	-

Sequence

Protein

• Length: 840 a.a.
• Molecular weight: 94195.17 Da
• Isoelectric Point: 4.7017

>NTDB_id=328366 FO444_RS12210 WP_098403553.1 2391514..2394036(-) (hexA) [Lactococcus lactis subsp. lactis strain IMAU11823]
MAEKISPGMQQYLDIKQDYPDAFLLFRMGDFYELFYDDAVNAAQILELTLTSRNKNSENPIPMAGVPHHAAAEYIDKLVD
LGYKVAVAEQMEDPKKAVGIVKRAVTQVITPGTTIDTANSVDNNFLVAIDFKDKHYALSYMDLSTGEFKVTELSEFSAVV
GEIASLKAREIVAGFTLDESQLKVFERQMNLLISEQIEIPENLLIDLSGLTALENQVASKLLAYVKETQMRDLSHLQEVE
HYEIKDFLQMDFATKSSLELTANKRENKKHGTLYWLLDETKTAMGTRMLRSWIDRPLVSNSAIQKRMEIVQIFLDHFFER
SDLIEALKGVYDLERLASRVSFGKAVPVDFLQLANSLSNVPAIKNILGMLNEAPLEELKSQLDEIPELSGLINSAISENA
SRTITEGGIIKKGYNAQLDKYREALENGTSWIGKLEADEKAKTGISTLRIDYNRKDGYYFHITQSQLNSVPEHFYRKATL
KNSERFGSQELTEIEEIMLEAREKSSSLEYDLFMGLRTETEQYIGRLQALAKTIAEIDCLQSLSVVAEKKGYIRPTLTDG
SRIVEIKGGRHAVVEAVMGAQEYVPNDIELPEQTDIQLITGPNMSGKSTYMRQFALTVIMAQIGSFVPAETANLPIFDAI
FTRIGASDNLISGESTFMVEMSEANHAIQKASSRSLIIFDELGRGTATYDGMALAQAIIEYVHDHIGAKTLFATHYHELT
DLDEALDHLDNVHVATLEQNGNVTFLHKITEGPADKSYGIHVAKIAGLPQPLLERADLILQKLENKPLPAKKVADEQEQL
SLFDFTENSSEIIEKIKRQNVDNMTAREALNFLWELKDSL

Nucleotide

• Length: 2523 bp

>NTDB_id=328366 FO444_RS12210 WP_098403553.1 2391514..2394036(-) (hexA) [Lactococcus lactis subsp. lactis strain IMAU11823]
ATGGCTGAAAAAATTTCACCAGGAATGCAACAATATTTAGACATCAAACAAGATTATCCCGATGCTTTCTTGCTCTTTCG
GATGGGTGATTTTTATGAGCTTTTCTATGATGATGCAGTGAATGCTGCCCAAATATTAGAATTAACCCTGACTTCAAGAA
ATAAAAATTCAGAAAATCCAATTCCAATGGCTGGTGTTCCCCACCATGCAGCAGCTGAATACATTGATAAATTGGTTGAT
TTAGGCTACAAAGTGGCTGTTGCTGAACAAATGGAAGACCCGAAAAAAGCGGTCGGAATTGTTAAACGGGCAGTAACACA
GGTGATTACCCCAGGGACAACGATTGACACTGCAAATTCGGTTGATAATAATTTCTTGGTGGCAATTGACTTCAAAGATA
AACATTATGCTCTTTCCTATATGGACTTATCAACTGGGGAATTCAAGGTGACAGAGCTCAGCGAATTTTCAGCGGTGGTG
GGAGAAATTGCTTCACTCAAGGCGCGGGAAATTGTAGCTGGTTTTACTTTAGATGAAAGTCAATTAAAAGTTTTTGAAAG
ACAAATGAATCTTTTGATTTCAGAACAAATTGAAATTCCTGAAAATTTACTGATAGATTTGTCAGGATTGACCGCCCTAG
AAAATCAAGTCGCTTCAAAATTGTTGGCTTACGTAAAAGAAACACAAATGCGTGATTTGAGTCACTTACAAGAAGTTGAA
CATTATGAAATTAAAGACTTTTTGCAAATGGACTTTGCGACAAAATCATCTTTAGAGCTGACGGCAAATAAAAGAGAAAA
TAAAAAACATGGCACACTTTATTGGTTGCTTGATGAGACGAAAACAGCGATGGGAACCAGAATGTTACGGTCGTGGATTG
ACCGTCCTTTGGTTTCAAATTCAGCCATTCAAAAACGAATGGAAATTGTTCAAATTTTCTTAGACCATTTCTTTGAGCGT
TCCGATTTGATAGAAGCCTTAAAAGGGGTCTATGATTTAGAACGTTTGGCTTCACGTGTTTCTTTTGGTAAGGCTGTTCC
GGTTGATTTTTTGCAGCTGGCTAATTCTTTATCAAATGTTCCTGCTATCAAAAATATTTTGGGAATGCTTAATGAAGCTC
CATTAGAAGAGTTAAAAAGCCAATTAGACGAAATTCCAGAATTATCTGGTTTAATTAATTCAGCTATTAGTGAGAATGCC
TCAAGAACGATTACTGAAGGGGGCATTATTAAAAAAGGCTACAATGCTCAATTAGATAAATATCGGGAGGCGCTTGAAAA
TGGGACTTCTTGGATTGGAAAATTGGAAGCAGATGAAAAAGCCAAGACAGGAATTTCCACACTACGAATTGATTATAATC
GTAAGGATGGTTATTATTTTCATATTACTCAAAGTCAGTTGAATAGTGTTCCTGAACATTTTTATCGGAAGGCAACTTTG
AAAAATTCTGAGCGTTTTGGTTCTCAGGAATTAACTGAAATTGAAGAAATTATGTTGGAAGCGCGTGAAAAATCATCATC
TCTAGAATATGATTTATTCATGGGCCTTCGGACTGAAACGGAGCAATATATTGGCAGACTACAAGCTCTAGCCAAAACAA
TTGCTGAAATTGATTGTTTACAAAGTCTATCTGTCGTTGCCGAAAAAAAAGGATATATCCGTCCGACGCTTACAGACGGT
TCAAGAATTGTTGAAATTAAAGGCGGTCGTCATGCGGTCGTTGAAGCGGTCATGGGTGCTCAAGAATATGTGCCAAATGA
TATTGAACTGCCTGAACAAACAGATATTCAACTCATCACAGGACCGAATATGTCAGGTAAATCAACCTACATGCGTCAAT
TTGCTTTGACGGTGATTATGGCTCAAATTGGATCTTTTGTTCCAGCCGAAACAGCCAATTTACCAATTTTTGATGCCATC
TTTACACGGATTGGTGCCAGTGATAACTTGATTTCAGGGGAATCGACCTTTATGGTTGAAATGTCTGAGGCCAATCATGC
CATTCAAAAGGCAAGCAGTCGCAGCCTGATTATTTTTGATGAATTAGGGCGAGGAACGGCAACTTATGATGGGATGGCTC
TAGCTCAAGCAATTATTGAATATGTTCATGACCATATTGGGGCAAAGACCTTGTTTGCTACGCATTATCATGAATTGACA
GACTTAGATGAAGCGCTCGATCATCTTGATAATGTCCATGTTGCTACCTTGGAGCAAAATGGGAATGTGACTTTTTTGCA
TAAAATAACAGAGGGGCCAGCTGATAAATCCTATGGGATTCATGTGGCGAAAATTGCAGGTTTACCACAGCCTTTGTTAG
AGCGAGCAGATTTGATTTTGCAGAAGTTAGAAAATAAACCTTTGCCTGCTAAAAAAGTTGCTGATGAACAAGAACAACTT
AGTTTATTTGATTTTACCGAAAATTCTTCAGAAATTATTGAAAAGATAAAAAGGCAAAATGTTGATAATATGACTGCAAG
AGAGGCATTAAATTTCTTGTGGGAACTTAAAGATTCACTTTGA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (124-237)

• MutS domain I (MutS_I) (7-116)

• MutS family domain IV (MutS_IV) (413-503)

• MutS domain III (MutS_III) (254-544)

• MutS domain V (MutS_V) (598-784)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	64.218	100	0.645
mutS	Pseudomonas stutzeri strain ATCC 17587	37.806	100	0.386