Detailed information NTG0328300

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EGH20_RS09975
• Genome accession: NZ_CP034026
• Coordinates: 1701866..1702726 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FQ20
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1696866..1707726

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGH20_RS09955 (EGH20_09955)	dapD	1697376..1698197 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
EGH20_RS09960 (EGH20_09960)	pgi	1698407..1700050 (-)	1644	WP_124723997.1	glucose-6-phosphate isomerase	-
EGH20_RS09970 (EGH20_09970)	pilG	1700560..1701792 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
EGH20_RS09975 (EGH20_09975)	pilD	1701866..1702726 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
EGH20_RS09980 (EGH20_09980)	coaE	1702723..1703355 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
EGH20_RS09985 (EGH20_09985)	-	1703348..1703557 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
EGH20_RS09990 (EGH20_09990)	pilF	1703643..1705319 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EGH20_RS10005 (EGH20_10005)	-	1705657..1706103 (-)	447	WP_124723998.1	DUF441 domain-containing protein	-
EGH20_RS10010 (EGH20_10010)	-	1706107..1707081 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
EGH20_RS10020 (EGH20_10020)	rplU	1707305..1707613 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=328300 EGH20_RS09975 WP_003689814.1 1701866..1702726(+) (pilD) [Neisseria gonorrhoeae strain FQ20]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=328300 EGH20_RS09975 WP_003689814.1 1701866..1702726(+) (pilD) [Neisseria gonorrhoeae strain FQ20]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441