Detailed information NTG0328251

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: EGH14_RS09965
• Genome accession: NZ_CP034024
• Coordinates: 1701362..1702222 (+)
• Length: 286 a.a.
• NCBI ID: WP_003689814.1
• Uniprot ID: A0AA44U9R8
• Organism: Neisseria gonorrhoeae strain FQ35
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1696362..1707222

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGH14_RS09945 (EGH14_09945)	dapD	1696872..1697693 (-)	822	WP_003689804.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-
EGH14_RS09950 (EGH14_09950)	pgi	1697903..1699546 (-)	1644	WP_124723997.1	glucose-6-phosphate isomerase	-
EGH14_RS09960 (EGH14_09960)	pilG	1700056..1701288 (+)	1233	WP_003689811.1	type 4 pilus assembly protein PilG	Machinery gene
EGH14_RS09965 (EGH14_09965)	pilD	1701362..1702222 (+)	861	WP_003689814.1	prepilin peptidase	Machinery gene
EGH14_RS09970 (EGH14_09970)	coaE	1702219..1702851 (+)	633	WP_003689816.1	dephospho-CoA kinase	-
EGH14_RS09975 (EGH14_09975)	-	1702844..1703053 (+)	210	WP_003696096.1	DNA gyrase inhibitor YacG	-
EGH14_RS09980 (EGH14_09980)	pilF	1703139..1704815 (-)	1677	WP_003689817.1	type IV-A pilus assembly ATPase PilB	Machinery gene
EGH14_RS09995 (EGH14_09995)	-	1705153..1705599 (-)	447	WP_124723998.1	DUF441 domain-containing protein	-
EGH14_RS10000 (EGH14_10000)	-	1705603..1706577 (-)	975	WP_003689819.1	polyprenyl synthetase family protein	-
EGH14_RS10010 (EGH14_10010)	rplU	1706801..1707109 (+)	309	WP_003691838.1	50S ribosomal protein L21	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31332.34 Da
• Isoelectric Point: 8.9561

>NTDB_id=328251 EGH14_RS09965 WP_003689814.1 1701362..1702222(+) (pilD) [Neisseria gonorrhoeae strain FQ35]
MSDLSVLSPFAVPLAAVLGLLVGSFLNVVIYRVPVMMERGWTVFAKEHLNLPLTDDESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLVAWQYGWSWITLGGLILTAFLISLTFIDADTQYLPDSMTLP
LIWLGLIFNLDGGFVPLQSAVLGAVAGYSSLWLLCAVYKLLTGKTGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGRHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVR

Nucleotide

• Length: 861 bp

>NTDB_id=328251 EGH14_RS09965 WP_003689814.1 1701362..1702222(+) (pilD) [Neisseria gonorrhoeae strain FQ35]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCAGTTTTGGGGCTGCTGGTCGGCAGCTTCCTGAA
TGTCGTCATTTACCGCGTACCCGTTATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAACATTTAAACCTGCCGCTGA
CCGACGATGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGCCGTGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGTTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGGTCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGTT
TGATACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACATTACCC
TTGATCTGGCTGGGGCTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATAGTTCATTATGGCTCTTATGTGCAGTGTATAAACTGCTCACAGGAAAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCTCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCGGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGAGATGA

Domains

Predicted by InterproScan.

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

• Type IV leader peptidase family (Peptidase_A24) (134-242)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	100	100	1
pilD	Vibrio cholerae strain A1552	44.792	100	0.451
pilD	Vibrio campbellii strain DS40M4	45.652	96.503	0.441
pilD	Acinetobacter baumannii D1279779	47.727	92.308	0.441
pilD	Acinetobacter nosocomialis M2	47.727	92.308	0.441