Detailed information
Bioinformatically predicted
Overview
| Name | pilL | Type | Machinery gene |
| Locus tag | EGH11_RS02745 | Genome accession | NZ_CP034018 |
| Coordinates | 451660..452130 (+) | Length | 156 a.a. |
| NCBI ID | WP_169577278.1 | Uniprot ID | - |
| Organism | Neisseria gonorrhoeae strain FQ82 | ||
| Function | type IV pilus (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 452200..508984 | 451660..452130 | flank | 70 |
Gene organization within MGE regions
Location: 451660..508984
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| EGH11_RS02745 (EGH11_02745) | pilL | 451660..452130 (+) | 471 | WP_169577278.1 | PilX family type IV pilin | Machinery gene |
| EGH11_RS02750 (EGH11_02750) | - | 452200..452508 (-) | 309 | WP_010951048.1 | AzlD family protein | - |
| EGH11_RS02755 (EGH11_02755) | - | 452505..453214 (-) | 710 | Protein_455 | AzlC family ABC transporter permease | - |
| EGH11_RS02760 (EGH11_02760) | dut | 453380..453832 (+) | 453 | WP_003690909.1 | dUTP diphosphatase | - |
| EGH11_RS02765 (EGH11_02765) | dapC | 453910..455097 (+) | 1188 | WP_003701073.1 | succinyldiaminopimelate transaminase | - |
| EGH11_RS02770 (EGH11_02770) | yaaA | 455253..456032 (+) | 780 | WP_003687925.1 | peroxide stress protein YaaA | - |
| EGH11_RS02785 (EGH11_02785) | - | 456563..457765 (+) | 1203 | WP_071198138.1 | integrase arm-type DNA-binding domain-containing protein | - |
| EGH11_RS02795 (EGH11_02795) | - | 458121..458390 (-) | 270 | WP_003687928.1 | hypothetical protein | - |
| EGH11_RS02800 (EGH11_02800) | - | 458585..459268 (-) | 684 | WP_003687929.1 | DUF2786 domain-containing protein | - |
| EGH11_RS14555 | - | 459582..459815 (-) | 234 | Protein_462 | hypothetical protein | - |
| EGH11_RS02810 (EGH11_02810) | - | 459926..460141 (-) | 216 | WP_003691538.1 | hypothetical protein | - |
| EGH11_RS02815 (EGH11_02815) | - | 460193..460684 (-) | 492 | WP_010359966.1 | siphovirus Gp157 family protein | - |
| EGH11_RS02820 (EGH11_02820) | - | 460681..460863 (-) | 183 | WP_003691535.1 | hypothetical protein | - |
| EGH11_RS02825 (EGH11_02825) | - | 461003..461689 (-) | 687 | WP_012503754.1 | hypothetical protein | - |
| EGH11_RS02830 (EGH11_02830) | - | 461758..461919 (-) | 162 | WP_003702497.1 | hypothetical protein | - |
| EGH11_RS02835 (EGH11_02835) | - | 461916..462191 (-) | 276 | WP_064661611.1 | hypothetical protein | - |
| EGH11_RS02840 (EGH11_02840) | - | 462344..462676 (-) | 333 | WP_003687946.1 | hypothetical protein | - |
| EGH11_RS02845 (EGH11_02845) | - | 462817..463104 (-) | 288 | WP_082278089.1 | hypothetical protein | - |
| EGH11_RS02850 (EGH11_02850) | - | 463101..463577 (-) | 477 | WP_012504141.1 | hypothetical protein | - |
| EGH11_RS02855 (EGH11_02855) | - | 463610..463810 (-) | 201 | WP_048654497.1 | hypothetical protein | - |
| EGH11_RS02860 (EGH11_02860) | - | 464008..464421 (-) | 414 | WP_003687963.1 | hypothetical protein | - |
| EGH11_RS02865 (EGH11_02865) | - | 464418..464879 (-) | 462 | WP_003687965.1 | helix-turn-helix transcriptional regulator | - |
| EGH11_RS02870 (EGH11_02870) | - | 464896..465333 (-) | 438 | WP_003687967.1 | hypothetical protein | - |
| EGH11_RS02875 (EGH11_02875) | - | 465446..466162 (-) | 717 | WP_003687969.1 | LexA family transcriptional regulator | - |
| EGH11_RS02880 (EGH11_02880) | - | 466231..466467 (+) | 237 | WP_003687971.1 | Cro/CI family transcriptional regulator | - |
| EGH11_RS02885 (EGH11_02885) | - | 466547..466702 (+) | 156 | WP_003691446.1 | hypothetical protein | - |
| EGH11_RS02890 (EGH11_02890) | - | 466679..466867 (-) | 189 | WP_003706568.1 | hypothetical protein | - |
| EGH11_RS02895 (EGH11_02895) | - | 467040..467267 (+) | 228 | WP_047949281.1 | helix-turn-helix domain-containing protein | - |
| EGH11_RS02900 (EGH11_02900) | - | 467264..468229 (+) | 966 | WP_124693283.1 | helix-turn-helix domain-containing protein | - |
| EGH11_RS02905 (EGH11_02905) | - | 468244..469026 (+) | 783 | WP_025456432.1 | ATP-binding protein | - |
| EGH11_RS02910 (EGH11_02910) | - | 469019..469249 (+) | 231 | WP_012503490.1 | hypothetical protein | - |
| EGH11_RS02915 (EGH11_02915) | - | 469340..469834 (+) | 495 | WP_082298905.1 | DUF3310 domain-containing protein | - |
| EGH11_RS02920 (EGH11_02920) | - | 470011..470160 (+) | 150 | WP_003692854.1 | hypothetical protein | - |
| EGH11_RS14055 | - | 470189..470470 (+) | 282 | WP_003689109.1 | hypothetical protein | - |
| EGH11_RS02925 (EGH11_02925) | - | 470461..470841 (+) | 381 | WP_017147222.1 | RusA family crossover junction endodeoxyribonuclease | - |
| EGH11_RS02935 (EGH11_02935) | - | 471108..471515 (+) | 408 | WP_003691430.1 | hypothetical protein | - |
| EGH11_RS02940 (EGH11_02940) | - | 471731..472765 (+) | 1035 | WP_229690641.1 | type I restriction endonuclease | - |
| EGH11_RS02945 (EGH11_02945) | - | 473564..474481 (+) | 918 | WP_124737170.1 | KilA-N domain-containing protein | - |
| EGH11_RS02950 (EGH11_02950) | - | 474774..475223 (+) | 450 | WP_003689093.1 | hypothetical protein | - |
| EGH11_RS02955 (EGH11_02955) | terL | 475285..476706 (+) | 1422 | WP_003689090.1 | phage terminase large subunit | - |
| EGH11_RS02960 (EGH11_02960) | - | 476703..478850 (+) | 2148 | WP_003691423.1 | phage portal protein | - |
| EGH11_RS02965 (EGH11_02965) | - | 478918..480075 (+) | 1158 | WP_010360058.1 | HK97 family phage prohead protease | - |
| EGH11_RS02970 (EGH11_02970) | - | 480116..481615 (+) | 1500 | WP_033910832.1 | hypothetical protein | - |
| EGH11_RS13710 (EGH11_02975) | - | 481622..481984 (+) | 363 | WP_003689082.1 | hypothetical protein | - |
| EGH11_RS02980 (EGH11_02980) | - | 481987..482517 (+) | 531 | WP_003689080.1 | head-tail connector protein | - |
| EGH11_RS02985 (EGH11_02985) | - | 482517..482999 (+) | 483 | WP_003703855.1 | HK97 gp10 family phage protein | - |
| EGH11_RS02990 (EGH11_02990) | - | 482996..483424 (+) | 429 | WP_003697213.1 | hypothetical protein | - |
| EGH11_RS02995 (EGH11_02995) | - | 483450..484223 (+) | 774 | WP_003692869.1 | hypothetical protein | - |
| EGH11_RS03000 (EGH11_03000) | - | 484284..484613 (+) | 330 | WP_003692871.1 | hypothetical protein | - |
| EGH11_RS03005 (EGH11_03005) | - | 484625..484891 (+) | 267 | WP_003689070.1 | hypothetical protein | - |
| EGH11_RS03010 (EGH11_03010) | - | 484891..485490 (+) | 600 | WP_003692874.1 | DUF2460 domain-containing protein | - |
| EGH11_RS03015 (EGH11_03015) | - | 485487..486341 (+) | 855 | WP_003698614.1 | DUF2163 domain-containing protein | - |
| EGH11_RS03020 (EGH11_03020) | - | 486343..486774 (+) | 432 | WP_003689064.1 | NlpC/P60 family protein | - |
| EGH11_RS03025 (EGH11_03025) | - | 486802..487080 (-) | 279 | WP_003689062.1 | XRE family transcriptional regulator | - |
| EGH11_RS03030 (EGH11_03030) | - | 487320..491465 (+) | 4146 | WP_071198284.1 | phage tail protein | - |
| EGH11_RS03035 (EGH11_03035) | - | 491577..491882 (+) | 306 | WP_003689058.1 | hypothetical protein | - |
| EGH11_RS03040 (EGH11_03040) | - | 491953..492423 (+) | 471 | WP_025455988.1 | hypothetical protein | - |
| EGH11_RS03045 (EGH11_03045) | - | 492424..492756 (+) | 333 | WP_003691408.1 | hypothetical protein | - |
| EGH11_RS03050 (EGH11_03050) | - | 492884..493117 (-) | 234 | WP_003692884.1 | hypothetical protein | - |
| EGH11_RS03055 (EGH11_03055) | - | 493125..493472 (-) | 348 | WP_003689051.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| EGH11_RS03060 (EGH11_03060) | - | 493472..493708 (-) | 237 | WP_003689049.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| EGH11_RS14405 | - | 493748..493873 (+) | 126 | WP_255294325.1 | hypothetical protein | - |
| EGH11_RS03070 (EGH11_03070) | - | 493915..494454 (+) | 540 | WP_003691405.1 | TIGR02594 family protein | - |
| EGH11_RS03075 (EGH11_03075) | - | 494455..494799 (+) | 345 | WP_003695464.1 | hypothetical protein | - |
| EGH11_RS13320 | - | 494783..494956 (+) | 174 | WP_165865812.1 | hypothetical protein | - |
| EGH11_RS03080 (EGH11_03080) | - | 495268..495417 (+) | 150 | WP_003691402.1 | hypothetical protein | - |
| EGH11_RS03085 (EGH11_03085) | - | 495447..498494 (+) | 3048 | WP_061182278.1 | tape measure protein | - |
| EGH11_RS03090 (EGH11_03090) | - | 498554..499033 (-) | 480 | WP_002241413.1 | DUF4760 domain-containing protein | - |
| EGH11_RS03100 (EGH11_03100) | - | 499375..500364 (-) | 990 | WP_003689040.1 | site-specific integrase | - |
| EGH11_RS03110 (EGH11_03110) | purM | 501053..502087 (+) | 1035 | WP_003689038.1 | phosphoribosylformylglycinamidine cyclo-ligase | - |
| EGH11_RS03120 (EGH11_03120) | - | 503085..503737 (+) | 653 | Protein_523 | IS1595 family transposase | - |
| EGH11_RS03125 (EGH11_03125) | - | 503871..505898 (+) | 2028 | WP_003689037.1 | BCCT family transporter | - |
| EGH11_RS03130 (EGH11_03130) | - | 505987..507540 (-) | 1554 | WP_003689036.1 | fatty acid--CoA ligase | - |
| EGH11_RS14410 | - | 507591..507719 (+) | 129 | WP_255294324.1 | hypothetical protein | - |
| EGH11_RS03135 (EGH11_03135) | - | 507791..508984 (-) | 1194 | WP_003700045.1 | SGNH/GDSL hydrolase family protein | - |
Sequence
Protein
Download Length: 156 a.a. Molecular weight: 17367.09 Da Isoelectric Point: 9.1761
>NTDB_id=328090 EGH11_RS02745 WP_169577278.1 451660..452130(+) (pilL) [Neisseria gonorrhoeae strain FQ82]
MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDDNDILKSRLEIFVSGYKM
NPKIAKKYSVSVSVDAEKPRAYRLVGVPNAGTGYTLSVWMNSVGDGYKCRDATSAQVYLETLSANTGCEAFSNRKK
MEQKGFTLIEMMIVVAILGIISVIAIPSYQSYIEKGYQSQLYTEMVGINNVLKQFILKNPQDDNDILKSRLEIFVSGYKM
NPKIAKKYSVSVSVDAEKPRAYRLVGVPNAGTGYTLSVWMNSVGDGYKCRDATSAQVYLETLSANTGCEAFSNRKK
Nucleotide
Download Length: 471 bp
>NTDB_id=328090 EGH11_RS02745 WP_169577278.1 451660..452130(+) (pilL) [Neisseria gonorrhoeae strain FQ82]
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCGCGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACGATAATGATATCCTCAAGAGCAGACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAGTGTCGATGCGGAAAAACCAAGGGCATACAGGTTGGTCGGTGT
TCCGAACGCGGGGACGGGTTATACTTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCACTT
CTGCCCAGGTCTATTTGGAGACCTTGTCCGCAAATACCGGCTGTGAAGCTTTCTCTAATCGTAAAAAATAG
ATGGAACAAAAAGGGTTTACATTGATTGAGATGATGATAGTTGTCGCGATACTCGGCATCATCAGCGTCATTGCCATACC
TTCTTATCAGAGTTATATTGAAAAAGGCTATCAGTCCCAGCTTTATACGGAGATGGTCGGTATCAACAATGTTCTCAAAC
AGTTTATTTTGAAAAATCCCCAGGACGATAATGATATCCTCAAGAGCAGACTGGAAATATTTGTCTCAGGCTATAAGATG
AATCCGAAAATTGCCAAAAAATATAGTGTTTCGGTAAGTGTCGATGCGGAAAAACCAAGGGCATACAGGTTGGTCGGTGT
TCCGAACGCGGGGACGGGTTATACTTTGTCGGTATGGATGAACAGCGTGGGCGACGGATACAAATGCCGTGATGCCACTT
CTGCCCAGGTCTATTTGGAGACCTTGTCCGCAAATACCGGCTGTGAAGCTTTCTCTAATCGTAAAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilL | Neisseria gonorrhoeae MS11 |
98.089 |
100 |
0.987 |
| pilX | Neisseria meningitidis 8013 |
84.713 |
100 |
0.853 |