Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FNV59_RS25300 Genome accession   NZ_CP041650
Coordinates   5574276..5574950 (+) Length   224 a.a.
NCBI ID   WP_054228340.1    Uniprot ID   A0ABU3URT3
Organism   Streptomyces sp. RLB1-8     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 5569276..5579950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNV59_RS25270 (FNV59_25635) - 5569318..5569689 (+) 372 Protein_5085 lasso peptide biosynthesis B2 protein -
  FNV59_RS25275 (FNV59_25640) - 5569811..5570722 (+) 912 WP_143601961.1 ATP-binding cassette domain-containing protein -
  FNV59_RS25280 (FNV59_25645) - 5570719..5571588 (+) 870 WP_143605450.1 ABC transporter permease -
  FNV59_RS25285 (FNV59_25650) - 5571609..5572130 (+) 522 WP_205522265.1 MauE/DoxX family redox-associated membrane protein -
  FNV59_RS25290 (FNV59_25655) - 5572136..5572867 (+) 732 WP_143601965.1 thioredoxin domain-containing protein -
  FNV59_RS25295 (FNV59_25660) mslH 5572864..5574186 (+) 1323 WP_143601966.1 lasso peptide C-terminal Trp epimerase -
  FNV59_RS25300 (FNV59_25665) vraR 5574276..5574950 (+) 675 WP_054228340.1 response regulator transcription factor Regulator
  FNV59_RS55235 (FNV59_25670) - 5575474..5575851 (+) 378 WP_143601968.1 hypothetical protein -
  FNV59_RS25310 (FNV59_25675) - 5576147..5577568 (+) 1422 WP_164404883.1 chaplin family protein -
  FNV59_RS25315 (FNV59_25680) - 5578368..5578607 (+) 240 WP_143601972.1 hypothetical protein -

Sequence

Protein


Download         Length: 224 a.a.        Molecular weight: 24016.85 Da        Isoelectric Point: 5.1216

>NTDB_id=327644 FNV59_RS25300 WP_054228340.1 5574276..5574950(+) (vraR) [Streptomyces sp. RLB1-8]
MAESVRVLIADDQALLRGSFRVLVDSTPGMEVVGEAGDGAMAVRLARELAPDVVLMDLRMPVLDGIAATREICSDETLTG
VRVLALTMFDMDEYVYPALQAGASGFMLKDASPSDLVDGIRVIATGEGVLAPTVTRRVIANFSRRGETPRPAPRLVGLTK
REHEVLVQIANGLSNAEISERLVISMPTVKTHVGSLLAKLHARDRAQLVIIAYESGLAERGMPT

Nucleotide


Download         Length: 675 bp        

>NTDB_id=327644 FNV59_RS25300 WP_054228340.1 5574276..5574950(+) (vraR) [Streptomyces sp. RLB1-8]
ATGGCCGAGTCGGTCCGGGTACTGATCGCGGACGACCAGGCACTGCTGCGCGGGAGCTTCCGGGTCCTCGTCGACTCCAC
ACCCGGCATGGAGGTCGTCGGCGAGGCCGGCGACGGCGCCATGGCGGTCCGGCTCGCCCGGGAACTCGCCCCGGACGTCG
TCCTGATGGACCTCCGGATGCCGGTTCTCGACGGCATCGCGGCCACCCGGGAGATCTGCTCCGACGAGACGCTGACCGGT
GTTCGGGTGCTGGCCCTGACCATGTTCGACATGGACGAGTACGTCTACCCGGCCCTCCAGGCGGGTGCCAGCGGCTTCAT
GCTGAAGGACGCCTCGCCGTCCGACCTGGTCGACGGCATCCGGGTCATCGCCACGGGCGAGGGTGTACTGGCCCCCACGG
TCACCCGGCGCGTCATCGCCAACTTCTCCCGGCGCGGCGAGACGCCCCGCCCCGCTCCACGACTCGTCGGTCTCACCAAG
CGGGAACACGAAGTCCTCGTCCAGATCGCCAACGGCCTGTCCAACGCGGAGATCTCCGAACGCCTGGTCATCAGCATGCC
GACCGTGAAGACCCACGTCGGCAGCCTCCTGGCCAAGCTGCACGCCCGGGACCGCGCACAGCTGGTCATCATCGCGTACG
AGAGCGGCCTGGCCGAGCGGGGAATGCCGACGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-120)

Bacterial regulatory proteins, luxR family (GerE)

(158-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

38.889

96.429

0.375
  degU Bacillus subtilis subsp. subtilis str. 168

36.564

100

0.371