Detailed information NTG0327585

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: EFD77_RS05025
• Genome accession: NZ_CP033982
• Coordinates: 1007474..1008460 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain P2D8C1
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1002474..1013460

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EFD77_RS05000 (EFD77_05225)	opp4B	1002688..1003650 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
EFD77_RS05005 (EFD77_05230)	opp4C	1003662..1004543 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
EFD77_RS05010 (EFD77_05235)	trpS	1004585..1005574 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
EFD77_RS05015 (EFD77_05240)	spxA	1005868..1006263 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
EFD77_RS05020 (EFD77_05245)	mecA	1006634..1007353 (+)	720	WP_001217728.1	adaptor protein MecA	-
EFD77_RS05025 (EFD77_05250)	coiA	1007474..1008460 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
EFD77_RS05030 (EFD77_05255)	pepF	1008508..1010316 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
EFD77_RS05035 (EFD77_05260)	yjbH	1010776..1011582 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
EFD77_RS05040 (EFD77_05265)	-	1011605..1011970 (-)	366	WP_156667995.1	truncated hemoglobin YjbI	-
EFD77_RS05045 (EFD77_05270)	-	1012074..1012667 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
EFD77_RS05050 (EFD77_05275)	-	1012853..1013200 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=327585 EFD77_RS05025 WP_000959282.1 1007474..1008460(+) (coiA) [Staphylococcus aureus strain P2D8C1]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=327585 EFD77_RS05025 WP_000959282.1 1007474..1008460(+) (coiA) [Staphylococcus aureus strain P2D8C1]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976