Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA   Type   Machinery gene
Locus tag   EHF44_RS17175 Genome accession   NZ_CP033969
Coordinates   3404614..3407145 (-) Length   843 a.a.
NCBI ID   WP_124684766.1    Uniprot ID   A0A3G8H427
Organism   Cupriavidus pauculus strain FDAARGOS_614     
Function   DNA uptake (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3399614..3412145
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EHF44_RS17160 (EHF44_17155) - 3400670..3401194 (-) 525 WP_124684763.1 gluconokinase -
  EHF44_RS17165 (EHF44_17160) edd 3401340..3403232 (-) 1893 WP_124684764.1 phosphogluconate dehydratase -
  EHF44_RS17170 (EHF44_17165) - 3403629..3404609 (+) 981 WP_124684765.1 MurR/RpiR family transcriptional regulator -
  EHF44_RS17175 (EHF44_17170) comA 3404614..3407145 (-) 2532 WP_124684766.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  EHF44_RS17180 (EHF44_17175) - 3407282..3408109 (-) 828 WP_124684767.1 TatD family hydrolase -
  EHF44_RS17185 (EHF44_17180) lolD 3408122..3408841 (-) 720 WP_253700121.1 lipoprotein-releasing ABC transporter ATP-binding protein LolD -
  EHF44_RS17190 (EHF44_17185) - 3408861..3410111 (-) 1251 WP_124684769.1 lipoprotein-releasing ABC transporter permease subunit -
  EHF44_RS17195 (EHF44_17190) - 3410217..3411344 (+) 1128 WP_124684770.1 hypothetical protein -

Sequence

Protein


Download         Length: 843 a.a.        Molecular weight: 90432.34 Da        Isoelectric Point: 11.4299

>NTDB_id=327525 EHF44_RS17175 WP_124684766.1 3404614..3407145(-) (comA) [Cupriavidus pauculus strain FDAARGOS_614]
MRVLLLALVAGCWLLQQQAELPASRAWWIGWAVAAMLAGALLVRGRPACWRDARWALVIALAALAAFGWAAWRAELRMDR
WLPPDLMARDLVAEGVVAGLPDDAGHRTRFRFNVARWDDDRAQRAGVSSVMLTWRDPPERLVPGQRYRLTVRLRPPRGLA
NPHGFDYAYWLLAEGIDATGYVREGQPAGGDDGALPWMVRVAAWRAAVRDHLRAAMPADARYGPVLVALVIGDQRGIAQA
DWEVFRRTGISHLVSISGLHITMVAGAAGAVARGLWRRSFGLGGVLRRPLPLRWPAQQAGLVVTVLAALGYGLLAGMQIP
ALRTVTMLIVAAVALWSGRAPPVSVVLAWAAGVAVAIDPWAVMSPGFWLSFGAVAVIFFHARRPEAGEQEAAGQEARGGG
APVIGQGFGGFVARCWRRIVRALVEAARAQWAVTVGLVPLTLLLFGQVSVVSCLANAVAIPVVSLFVTPMALASAVLPAD
VATMLLGVAHALLASLVDGLAWLAAPSWAVWEAAQPGWLVTGLALAGVVVLLTPGRVRLPRLRAKAGGRALPRWPGAVLM
LPMLLGGRDAIAEGEMRVTALDVGQGTAVLVETRRHALLYDAGPSYVSGASAGAQVVVPYLRAVGVRRLDMLMVSHEDAD
HAGGVLDVMRAVPVSARQTAAAPGHRLLTLPGRPWVPCAAGAGWVWDGVRFDVMHPTAEDLTRATLSSNARSCVLRVATA
HRSVLLTGDIGVNEELGFIARAPPAQVRADVLVVPHHGSGTSSHVAFLRAVQPAVAVFQLGFANRYRHPREDVWQRYGRA
GIARYRTDETGAVTIVTDGDGLRVVPYRQHVRRYWRDRPPAPR

Nucleotide


Download         Length: 2532 bp        

>NTDB_id=327525 EHF44_RS17175 WP_124684766.1 3404614..3407145(-) (comA) [Cupriavidus pauculus strain FDAARGOS_614]
ATGCGCGTGCTGCTGCTGGCGTTGGTGGCGGGCTGCTGGCTGCTGCAGCAACAGGCTGAACTGCCGGCGTCGCGCGCGTG
GTGGATCGGCTGGGCCGTGGCGGCCATGCTGGCGGGCGCGCTGCTGGTGCGCGGACGCCCGGCCTGTTGGCGTGATGCGC
GCTGGGCACTGGTCATCGCTCTGGCCGCGCTGGCGGCCTTCGGCTGGGCCGCGTGGCGCGCGGAGCTGCGCATGGACCGC
TGGCTGCCGCCGGACCTGATGGCGCGCGACCTGGTTGCCGAGGGCGTGGTGGCGGGCCTGCCCGACGACGCCGGCCATCG
CACGCGGTTCCGCTTCAACGTGGCGCGCTGGGACGACGATCGGGCGCAACGCGCCGGCGTGTCGTCGGTCATGCTGACGT
GGCGCGATCCACCGGAACGGCTGGTGCCGGGGCAGCGCTACCGGCTGACGGTGCGGCTGCGGCCGCCGCGCGGGCTGGCC
AATCCGCATGGGTTCGACTACGCGTACTGGCTGCTCGCCGAAGGGATCGACGCCACGGGCTACGTGCGGGAGGGCCAGCC
AGCCGGGGGCGACGACGGCGCGCTGCCGTGGATGGTCCGCGTCGCGGCGTGGCGGGCGGCCGTGCGCGACCACCTGCGCG
CGGCGATGCCGGCCGATGCGCGGTACGGGCCGGTGCTGGTGGCACTGGTGATCGGCGACCAGCGCGGCATTGCGCAGGCC
GACTGGGAGGTGTTCCGGCGCACCGGCATCTCGCATCTGGTCAGCATTTCGGGCCTGCATATCACGATGGTCGCCGGGGC
GGCCGGCGCGGTGGCGCGCGGGCTGTGGCGACGGTCGTTCGGCCTGGGCGGCGTGCTGCGGCGGCCCTTGCCGCTGCGCT
GGCCGGCGCAGCAGGCCGGACTGGTGGTGACGGTGCTGGCCGCGCTCGGCTATGGCCTGCTGGCCGGCATGCAGATTCCG
GCGCTGCGGACGGTCACGATGCTGATCGTGGCGGCCGTCGCGCTATGGAGCGGCCGGGCGCCGCCGGTGTCGGTCGTGCT
GGCGTGGGCGGCCGGGGTGGCGGTGGCCATCGACCCGTGGGCCGTGATGTCGCCCGGCTTCTGGCTGTCGTTTGGCGCCG
TGGCGGTGATCTTCTTCCATGCGCGGCGGCCGGAGGCGGGCGAGCAGGAAGCGGCGGGGCAGGAAGCGCGGGGCGGCGGG
GCGCCTGTCATCGGCCAGGGCTTCGGCGGGTTCGTCGCGCGCTGCTGGCGGCGGATTGTCCGGGCACTGGTCGAGGCCGC
GCGGGCGCAGTGGGCGGTGACCGTCGGGCTCGTGCCGTTGACGCTGCTGCTGTTCGGGCAGGTGTCGGTGGTCTCGTGCC
TGGCCAATGCCGTGGCAATACCGGTCGTCAGCCTGTTCGTGACGCCAATGGCGCTGGCCAGCGCCGTACTGCCCGCCGAC
GTGGCGACGATGCTGCTCGGCGTGGCCCACGCGCTGCTGGCATCGCTGGTGGACGGGCTGGCGTGGCTGGCGGCGCCGTC
ATGGGCGGTATGGGAAGCCGCGCAGCCGGGGTGGCTGGTCACCGGCCTGGCGCTGGCCGGTGTGGTGGTGCTGCTGACAC
CGGGCCGGGTGCGGCTGCCCCGGTTGCGGGCGAAAGCGGGTGGCCGGGCACTGCCGCGCTGGCCCGGTGCGGTACTGATG
CTGCCGATGTTGCTCGGCGGGCGCGACGCCATCGCGGAAGGGGAAATGCGGGTCACCGCGCTCGATGTCGGGCAGGGCAC
CGCCGTGCTGGTCGAAACGCGCCGGCATGCGCTGCTCTATGACGCGGGGCCGTCCTACGTATCGGGCGCCAGCGCGGGCG
CGCAGGTCGTCGTGCCGTACCTGCGTGCCGTCGGCGTGCGCCGGCTGGACATGCTGATGGTCAGCCACGAGGACGCGGAC
CACGCGGGTGGCGTGCTCGATGTCATGCGCGCGGTGCCGGTCAGCGCGCGCCAGACCGCCGCTGCGCCCGGTCACCGGCT
CCTGACCCTGCCGGGACGGCCGTGGGTACCTTGTGCTGCCGGGGCAGGGTGGGTGTGGGACGGCGTCCGGTTCGACGTGA
TGCATCCCACGGCGGAAGACCTGACGCGCGCGACGCTATCGAGCAACGCCAGAAGCTGTGTCCTGCGCGTGGCAACGGCC
CACCGCAGCGTGCTGCTGACGGGCGATATTGGCGTGAACGAGGAGCTGGGGTTCATCGCCCGGGCGCCGCCGGCCCAGGT
GCGGGCCGACGTGCTGGTCGTGCCGCACCATGGCAGCGGCACGTCGTCGCATGTGGCGTTCCTGCGGGCCGTCCAGCCGG
CGGTGGCGGTCTTCCAGCTCGGGTTTGCGAACCGCTACCGGCATCCGCGCGAGGACGTCTGGCAGCGGTACGGGCGAGCC
GGCATCGCAAGGTACCGGACCGACGAGACCGGCGCGGTCACGATCGTCACGGATGGCGACGGGCTGCGGGTGGTGCCGTA
TCGGCAGCATGTCCGCCGCTACTGGCGCGACCGGCCGCCGGCGCCGCGTTGA

Domains

Predicted by InterproScan.

Domain of unknown function (DUF4131) (DUF4131)

(26-185)

Competence protein (Competence)

(229-533)

Metallo-beta-lactamase superfamily (Lactamase_B)

(582-775)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3G8H427

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA Ralstonia pseudosolanacearum GMI1000

48.443

100

0.498

Multiple sequence alignment