Detailed information NTG0327452

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: EG882_RS06145
• Genome accession: NZ_CP033967
• Coordinates: 1172751..1173914 (+)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain 1B-23
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 1167751..1178914

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EG882_RS06125 (EG882_06125)	-	1168137..1169333 (+)	1197	WP_124692699.1	glycosyltransferase	-
EG882_RS06130 (EG882_06130)	-	1169466..1170542 (+)	1077	WP_003151382.1	MraY family glycosyltransferase	-
EG882_RS06135 (EG882_06135)	-	1170641..1171876 (-)	1236	WP_025285355.1	LCP family protein	-
EG882_RS06140 (EG882_06140)	-	1171881..1172528 (-)	648	WP_007407485.1	YigZ family protein	-
EG882_RS06145 (EG882_06145)	degS	1172751..1173914 (+)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
EG882_RS06150 (EG882_06150)	degU	1173991..1174680 (+)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
EG882_RS06155 (EG882_06155)	-	1174778..1175626 (+)	849	WP_003151387.1	DegV family protein	-
EG882_RS06160 (EG882_06160)	comFA	1175735..1177120 (+)	1386	WP_124692700.1	DEAD/DEAH box helicase	Machinery gene
EG882_RS06165 (EG882_06165)	-	1177178..1177462 (+)	285	WP_007407481.1	competence protein ComFB	-
EG882_RS06170 (EG882_06170)	comFC	1177468..1178157 (+)	690	WP_199022660.1	phosphoribosyltransferase family protein	Machinery gene
EG882_RS06175 (EG882_06175)	-	1178231..1178650 (+)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=327452 EG882_RS06145 WP_007407484.1 1172751..1173914(+) (degS) [Bacillus velezensis strain 1B-23]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=327452 EG882_RS06145 WP_007407484.1 1172751..1173914(+) (degS) [Bacillus velezensis strain 1B-23]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TCTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAACAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATCATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTGCGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGTATCGGAGACACGGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAACGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951