Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   FNV66_RS12470 Genome accession   NZ_CP041607
Coordinates   2400869..2401531 (+) Length   220 a.a.
NCBI ID   WP_143600952.1    Uniprot ID   -
Organism   Streptomyces sp. S1D4-14     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2395869..2406531
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FNV66_RS12445 (FNV66_12610) mug 2396877..2397425 (+) 549 WP_097283763.1 G/U mismatch-specific DNA glycosylase -
  FNV66_RS12450 (FNV66_12615) - 2397435..2397872 (-) 438 WP_143600949.1 hypothetical protein -
  FNV66_RS12455 (FNV66_12620) - 2397914..2398639 (-) 726 WP_143600950.1 ABC transporter permease subunit -
  FNV66_RS12460 (FNV66_12625) - 2398636..2399577 (-) 942 WP_054229013.1 ABC transporter ATP-binding protein -
  FNV66_RS12465 (FNV66_12630) - 2399685..2400854 (+) 1170 WP_143600951.1 sensor histidine kinase -
  FNV66_RS12470 (FNV66_12635) vraR 2400869..2401531 (+) 663 WP_143600952.1 response regulator transcription factor Regulator
  FNV66_RS12475 (FNV66_12640) - 2401654..2402811 (+) 1158 WP_054229016.1 ROK family transcriptional regulator -
  FNV66_RS12480 (FNV66_12645) - 2402916..2403677 (-) 762 WP_060900464.1 GntR family transcriptional regulator -
  FNV66_RS12485 (FNV66_12650) - 2403933..2404817 (-) 885 WP_143600953.1 RNA polymerase sigma-70 factor -
  FNV66_RS12490 (FNV66_12655) - 2404973..2405803 (+) 831 WP_143600954.1 alpha/beta fold hydrolase -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 23342.97 Da        Isoelectric Point: 4.9794

>NTDB_id=327084 FNV66_RS12470 WP_143600952.1 2400869..2401531(+) (vraR) [Streptomyces sp. S1D4-14]
MPVTVLLVDDEPLVRAGLRAVLAAQRDIEVVGEAADGAAVIPLVRQLRPDVVAMDVRMPLMDGIEATRALLRTVSDPPKI
LVVTTFENDEYVYEALRAGADGFLLKRARPAEIVHAVRLVAEGESLLFPASVRQLAAEYGDGGGNPAARAAMERAALTER
EAEVLRLMARGLSNAEIAGRLIVGTETVKSHVSAVLAKLGARDRTQAVIAAYESGFVAPG

Nucleotide


Download         Length: 663 bp        

>NTDB_id=327084 FNV66_RS12470 WP_143600952.1 2400869..2401531(+) (vraR) [Streptomyces sp. S1D4-14]
ATGCCGGTCACCGTTCTCCTCGTCGACGACGAACCGCTCGTCCGCGCGGGTCTGCGGGCCGTCCTGGCGGCGCAGCGCGA
CATCGAGGTCGTGGGAGAAGCGGCCGACGGCGCCGCGGTGATCCCGCTCGTGCGGCAGCTGCGGCCGGACGTCGTCGCCA
TGGACGTCCGCATGCCGCTCATGGACGGCATCGAGGCCACGCGCGCGCTCCTGCGGACCGTGAGCGATCCCCCGAAGATC
CTCGTCGTGACCACGTTCGAGAACGACGAGTACGTCTACGAGGCGCTGCGCGCGGGTGCCGACGGTTTTCTGCTGAAGCG
GGCCAGGCCCGCCGAGATCGTGCACGCCGTGCGGCTCGTCGCGGAGGGCGAGTCGCTGCTGTTCCCTGCGTCCGTACGGC
AGTTGGCGGCCGAGTACGGGGACGGTGGCGGGAATCCGGCGGCGCGGGCGGCCATGGAGCGCGCCGCGCTGACCGAGCGG
GAGGCGGAGGTGCTGCGGCTGATGGCCCGGGGGCTGTCGAACGCGGAGATCGCCGGGCGGCTGATCGTCGGAACCGAGAC
GGTCAAGTCGCACGTCAGCGCCGTACTGGCGAAGCTGGGAGCCCGGGACCGTACGCAGGCGGTCATCGCGGCGTACGAGT
CGGGGTTCGTGGCCCCCGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-118)

Bacterial regulatory proteins, luxR family (GerE)

(156-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.553

99.545

0.414
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.368