Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EGX82_RS10135 Genome accession   NZ_CP033822
Coordinates   1927704..1928930 (+) Length   408 a.a.
NCBI ID   WP_000918412.1    Uniprot ID   A0AAV3JKF5
Organism   Streptococcus agalactiae strain FDAARGOS_512     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1922704..1933930
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX82_RS10105 (EGX82_10105) - 1922921..1923370 (-) 450 WP_001039193.1 DUF1836 domain-containing protein -
  EGX82_RS10110 (EGX82_10110) - 1923462..1924745 (-) 1284 WP_000161684.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EGX82_RS10115 (EGX82_10115) - 1924747..1925919 (-) 1173 WP_001873466.1 hydroxymethylglutaryl-CoA synthase -
  EGX82_RS10120 (EGX82_10120) - 1926073..1926912 (+) 840 WP_000158597.1 thymidylate synthase -
  EGX82_RS10125 (EGX82_10125) - 1926992..1927486 (+) 495 WP_000166043.1 dihydrofolate reductase -
  EGX82_RS10135 (EGX82_10135) clpX 1927704..1928930 (+) 1227 WP_000918412.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EGX82_RS10140 (EGX82_10140) yihA 1928941..1929537 (+) 597 WP_000796925.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EGX82_RS10145 (EGX82_10145) - 1929518..1930147 (-) 630 WP_000140673.1 TetR/AcrR family transcriptional regulator -
  EGX82_RS11380 - 1930419..1930742 (+) 324 WP_001867206.1 HXXEE domain-containing protein -
  EGX82_RS10160 (EGX82_10160) - 1930900..1931550 (+) 651 WP_000120090.1 HXXEE domain-containing protein -
  EGX82_RS10165 (EGX82_10165) - 1931680..1933056 (+) 1377 WP_000427477.1 amino acid permease -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44850.28 Da        Isoelectric Point: 4.4424

>NTDB_id=326144 EGX82_RS10135 WP_000918412.1 1927704..1928930(+) (clpX) [Streptococcus agalactiae strain FDAARGOS_512]
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKN
ILFIVGGAFDGIEDLVKQRLGEKIIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGT
DKPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=326144 EGX82_RS10135 WP_000918412.1 1927704..1928930(+) (clpX) [Streptococcus agalactiae strain FDAARGOS_512]
ATGGCTGGGAATCGTAATAACGATATGAATGTCTATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAATGGTGTTTTCATTTGTAATGAATGTGTGGCCTTATCACAAGAAATTATTAAGGAAGAATTAGCTGAGGAAG
TACTTGCTGATTTAGCAGAAGTACCAAAACCTAAGGAACTATTAGAAATATTAAATCAATATGTTGTAGGGCAAGATCGT
GCTAAACGTGCTTTAGCAGTTGCTGTCTACAATCATTACAAGCGTGTTAGTTATACCGAGAGTAGTGACGATGATGTAGA
TTTGCAAAAATCCAACATTTTGATGATTGGTCCAACTGGCTCAGGAAAAACCTTCTTAGCACAAACACTAGCTAAAAGCC
TTAATGTACCGTTTGCTATTGCAGATGCGACTTCATTGACCGAAGCAGGATACGTTGGAGAAGATGTTGAGAATATTCTT
CTTAAATTGATTCAAGCTGCTGATTATAATGTCGAACGTGCTGAGCGTGGTATTATCTACGTTGATGAAATAGATAAAAT
TGCTAAGAAAGGCGAAAATGTTTCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTATTG
AGGGTACGGTAGCAAGTGTTCCCCCACAGGGTGGGCGTAAACATCCTAACCAAGAAATGATTCAAATTAATACCAAGAAC
ATCCTTTTTATTGTCGGTGGTGCTTTTGATGGTATTGAAGACCTTGTGAAGCAACGTTTAGGCGAAAAAATTATTGGTTT
TGGACAGACAAGCCGCAAAATTGATGACAACGCTTCTTATATGCAAGAGATAATTTCTGAGGATATTCAAAAGTTTGGAC
TGATTCCAGAGTTTATTGGCCGTTTACCAGTAGTTGCAGCGTTAGAACTTCTTACTGCAGAAGATCTGGTTCGTATTCTG
ACAGAACCACGCAATGCTTTGGTTAAACAATACCAAACCTTATTATCTTATGATGGTGTAGAATTGGAATTTGATCAGGA
TGCTCTATTGGCTATCGCTGATAAGGCTATCGAGCGCAAGACTGGTGCACGTGGTTTACGTTCTATTATTGAAGAAACGA
TGCTTGATATCATGTTTGAAATTCCAAGCCAAGAAGATGTAACAAAAGTTCGTATCACAAAGGCTGCTGTTGAGGGTACT
GACAAGCCTGTTTTAGAGACGGCTTAG

Domains

Predicted by InterProScan.

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-390)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

90.709

100

0.909
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58

98.039

0.569

Multiple sequence alignment