Detailed information NTG0325922

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: EGX96_RS04960
• Genome accession: NZ_CP033810
• Coordinates: 965267..966496 (+)
• Length: 409 a.a.
• NCBI ID: WP_000728358.1
• Uniprot ID: A0AAW3HT93
• Organism: Streptococcus sp. FDAARGOS_520
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 960267..971496

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGX96_RS04935 (EGX96_04935)	-	961429..964008 (+)	2580	WP_000154437.1	YfhO family protein	-
EGX96_RS04955 (EGX96_04955)	rlmH	964587..965066 (-)	480	WP_000768335.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
EGX96_RS04960 (EGX96_04960)	htrA	965267..966496 (+)	1230	WP_000728358.1	S1C family serine protease	Regulator
EGX96_RS04965 (EGX96_04965)	spo0J	966594..967367 (+)	774	WP_000456087.1	ParB/RepB/Spo0J family partition protein	Regulator
EGX96_RS04970 (EGX96_04970)	dnaA	967566..968927 (+)	1362	WP_000138202.1	chromosomal replication initiator protein DnaA	-
EGX96_RS04975 (EGX96_04975)	dnaN	969082..970218 (+)	1137	WP_000581132.1	DNA polymerase III subunit beta	-
EGX96_RS04980 (EGX96_04980)	-	970276..971169 (+)	894	WP_000987446.1	diacylglycerol kinase family protein	-
EGX96_RS04985 (EGX96_04985)	-	971179..971376 (+)	198	WP_000285199.1	DUF951 domain-containing protein	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 43118.59 Da
• Isoelectric Point: 9.5271

>NTDB_id=325922 EGX96_RS04960 WP_000728358.1 965267..966496(+) (htrA) [Streptococcus sp. FDAARGOS_520]
MKKKLVSSLLKCSLIIIVSFAGGAFASFVMNHNDNIPNGGVTKTSKVNYNNITPTTKAVKKVQNSVVSVINYKQQESRSD
LSDFYSHFFGNQGGNTDKGLQVYGEGSGVIYKKDGKNAYVVTNNHVIDGAKQIEIQLADGSKAVGKLVGSDTYSDLAVVK
IPSDKVSNIAEFADSSKLNIGETAIAIGSPLGTEYANSVTQGIVSSLKRTVTMTNEEGQTVSTNAIQTDAAINPGNSGGA
LINIEGQVIGINSSKISSTSNQTSGQSSGNSVEGMGFAIPSNDVVKIINQLESNGQVERPALGISMAGLSNLPSDVISKL
KIPSNVTNGIVVASIQSGMPAQGKLKKYDVITKVDDKEVVSPSDLQSLLYGHQVGDSITVTFYRGENKQTVTIKLTKTSK
DLAKQRANN

Nucleotide

• Length: 1230 bp

>NTDB_id=325922 EGX96_RS04960 WP_000728358.1 965267..966496(+) (htrA) [Streptococcus sp. FDAARGOS_520]
GTGAAAAAAAAATTAGTCTCATCACTTCTAAAGTGTTCTCTAATCATTATTGTTAGCTTTGCTGGTGGAGCATTTGCTAG
TTTTGTCATGAATCATAATGACAATATTCCAAATGGTGGTGTCACTAAAACTAGTAAAGTAAATTATAATAACATAACGC
CTACAACAAAAGCTGTTAAAAAGGTACAAAATAGTGTTGTTTCTGTTATCAATTATAAACAACAAGAGAGTCGTTCTGAC
CTATCAGACTTCTATAGTCATTTTTTTGGTAATCAGGGGGGCAACACTGATAAGGGCTTACAAGTTTACGGTGAAGGCTC
TGGAGTCATCTATAAAAAAGATGGTAAAAATGCCTATGTTGTCACTAATAACCACGTCATTGATGGGGCTAAACAAATTG
AAATTCAACTAGCTGATGGCTCAAAAGCAGTTGGGAAACTTGTTGGGTCAGATACCTACTCTGATTTAGCCGTCGTCAAA
ATTCCATCAGATAAGGTTTCAAATATTGCAGAATTTGCTGATTCATCAAAACTCAACATTGGTGAAACTGCTATAGCGAT
CGGAAGCCCTCTTGGAACTGAGTATGCAAATTCTGTAACTCAAGGTATTGTATCTAGTTTAAAAAGAACTGTAACAATGA
CTAATGAAGAAGGACAAACAGTTTCTACAAATGCTATCCAGACTGATGCTGCTATCAATCCTGGTAATTCAGGTGGAGCA
CTTATCAATATTGAAGGACAGGTTATTGGAATTAATTCTAGTAAAATTTCTTCTACATCAAATCAAACCTCAGGACAATC
GTCAGGAAATAGCGTTGAAGGTATGGGATTTGCCATTCCTTCAAATGATGTTGTTAAGATTATCAATCAACTTGAGAGTA
ACGGACAAGTAGAGAGACCTGCTCTAGGTATTTCTATGGCTGGATTAAGTAATTTACCATCCGATGTTATTAGTAAACTG
AAAATCCCAAGTAATGTTACTAATGGTATTGTAGTAGCATCTATCCAATCTGGCATGCCAGCTCAAGGCAAACTAAAGAA
ATACGATGTCATTACTAAAGTTGACGATAAAGAAGTAGTATCTCCAAGTGATTTACAAAGTTTACTCTATGGCCACCAGG
TAGGGGATTCCATAACAGTAACCTTTTATCGTGGTGAAAATAAACAAACAGTCACTATAAAACTTACTAAAACTAGTAAA
GATTTAGCTAAACAACGAGCAAATAACTAA

Domains

Predicted by InterproScan.

• Trypsin-like peptidase domain (Trypsin_2) (106-251)

• PDZ domain (PDZ_2) (300-395)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	63.104	96.088	0.606
htrA	Streptococcus gordonii str. Challis substr. CH1	57.357	98.044	0.562
htrA	Streptococcus mitis NCTC 12261	56.281	97.311	0.548
htrA	Streptococcus pneumoniae TIGR4	54.791	99.511	0.545
htrA	Streptococcus pneumoniae Rx1	54.791	99.511	0.545
htrA	Streptococcus pneumoniae D39	54.791	99.511	0.545
htrA	Streptococcus pneumoniae R6	54.791	99.511	0.545