Detailed information    

insolico Bioinformatically predicted

Overview

Name   pepF   Type   Regulator
Locus tag   EGX72_RS07835 Genome accession   NZ_CP033809
Coordinates   1476211..1478016 (-) Length   601 a.a.
NCBI ID   WP_001282902.1    Uniprot ID   A0A0E1ELA1
Organism   Streptococcus sp. FDAARGOS_521     
Function   degradation of XIP; competence shut-off (predicted from homology)   
Competence regulation

Genomic Context

Location: 1471211..1483016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX72_RS07815 (EGX72_07810) - 1472892..1473377 (-) 486 WP_000190192.1 LURP-one-related/scramblase family protein -
  EGX72_RS07820 (EGX72_07815) prsA 1473619..1474548 (-) 930 WP_000857822.1 peptidylprolyl isomerase PrsA -
  EGX72_RS07825 (EGX72_07820) - 1474609..1475316 (-) 708 WP_000250853.1 O-methyltransferase -
  EGX72_RS07830 (EGX72_07825) - 1475390..1476016 (-) 627 WP_000736935.1 HAD hydrolase-like protein -
  EGX72_RS07835 (EGX72_07830) pepF 1476211..1478016 (-) 1806 WP_001282902.1 oligoendopeptidase F Regulator
  EGX72_RS07840 (EGX72_07835) coiA 1478032..1478979 (-) 948 WP_000903642.1 competence protein CoiA Machinery gene
  EGX72_RS07845 (EGX72_07840) - 1479031..1480182 (-) 1152 WP_001086200.1 MFS transporter -
  EGX72_RS07855 (EGX72_07850) - 1480255..1480974 (-) 720 WP_001234957.1 16S rRNA pseudouridine(516) synthase -
  EGX72_RS07860 (EGX72_07855) - 1481070..1482026 (+) 957 WP_000523788.1 glutathione S-transferase family protein -
  EGX72_RS07865 (EGX72_07860) - 1482098..1482799 (-) 702 WP_001263956.1 glucosamine-6-phosphate deaminase -

Sequence

Protein


Download         Length: 601 a.a.        Molecular weight: 69604.56 Da        Isoelectric Point: 4.6508

>NTDB_id=325880 EGX72_RS07835 WP_001282902.1 1476211..1478016(-) (pepF) [Streptococcus sp. FDAARGOS_521]
MSDNRSHIEEKYQWDLTTVFATDELWETEVVELTQAIDNAKGFSGHLLDSSQSLLEITEVELDLSRRLEKVYVYASMKND
QDTTVAKYQEFQAKATALYAKFSETFSFYEPELLQLSESDYQSFLLEMPDLQKYDHFFEKIFANKPHVLSQNEEELLAGA
SEIFGAAGETFEILDNADMVFPVVKNAKGEEVELTHGNFISLMESSDRTVRKEAYQAMYSTYEQFQHTYAKTLQTNVKSQ
NFKARVHHYQSARQSALSANFIPEEVYETLIKTVNHHLPLLHRYMKLRQKVLGLDDLKMYDVYTPLSQMDMSFTYDEALK
KSEEVLAIFGEAYSERVHRAFTERWIDVHVNKGKRSGAYSGGSYDTNAFMLLNWQDTLDNLYTLVHETGHSLHSTFTREN
QPYVYGDYSIFLAEIASTTNENILTETLLKEVKDDKNRFAILNHYLDGFKGTIFRQTQFAEFEHAIHVADQEGQVLTSEY
LNNLYAELNEKYYGLTKEDNHFIQYEWARIPHFYYNYYVFQYATGFAAANYLAERIVNGNPEDKEAYLNYLKAGNSDYPL
NVIAKAGVDMTSADYLDAAFRVFEERLVELENLVAKGVHND

Nucleotide


Download         Length: 1806 bp        

>NTDB_id=325880 EGX72_RS07835 WP_001282902.1 1476211..1478016(-) (pepF) [Streptococcus sp. FDAARGOS_521]
ATGTCAGACAATCGCTCACATATTGAAGAAAAATACCAATGGGATTTAACTACTGTCTTTGCGACTGATGAGTTATGGGA
AACTGAAGTGGTAGAGCTTACTCAAGCCATCGATAATGCAAAGGGTTTTTCAGGTCATCTGTTGGACTCAAGCCAATCTT
TATTGGAGATCACGGAGGTTGAATTAGATTTATCTCGCCGTTTAGAAAAAGTTTATGTCTATGCTTCAATGAAAAATGAC
CAAGACACCACTGTTGCGAAATATCAAGAATTTCAAGCGAAAGCGACAGCGCTCTATGCAAAATTTAGTGAAACATTTTC
GTTTTACGAGCCAGAACTATTGCAACTTTCAGAGTCTGATTACCAGTCATTCCTTTTAGAAATGCCTGACTTGCAAAAAT
ATGATCATTTCTTTGAGAAAATATTTGCAAATAAACCTCATGTCTTATCTCAAAACGAAGAAGAATTGTTAGCTGGTGCT
AGTGAGATTTTTGGAGCAGCTGGTGAGACATTTGAAATCCTTGATAATGCAGATATGGTCTTCCCAGTTGTAAAAAATGC
AAAAGGTGAGGAAGTTGAGCTTACACATGGTAATTTCATTTCCCTTATGGAATCTAGCGATAGGACGGTTCGAAAAGAAG
CATATCAAGCTATGTATAGCACATATGAACAATTCCAGCATACTTACGCTAAAACATTACAAACAAATGTGAAATCTCAA
AATTTTAAGGCTCGTGTGCATCATTATCAATCAGCACGCCAATCAGCTCTATCTGCCAATTTTATTCCAGAAGAGGTCTA
CGAAACTCTAATTAAGACAGTTAATCATCATTTACCGCTCTTACATCGTTATATGAAGTTGCGTCAAAAAGTTCTTGGGC
TAGATGATTTGAAGATGTATGACGTATATACACCCCTTTCTCAAATGGATATGAGTTTTACTTATGATGAAGCTCTAAAA
AAATCAGAGGAGGTTCTAGCTATTTTTGGCGAAGCATATTCTGAACGTGTTCATCGTGCTTTTACTGAACGTTGGATTGA
TGTCCATGTTAACAAAGGAAAGAGGTCAGGCGCTTATTCAGGTGGATCTTATGACACTAATGCTTTCATGCTTCTTAACT
GGCAAGATACTTTAGATAATCTTTATACGCTGGTGCATGAAACTGGACATAGTCTACACTCGACGTTTACTCGTGAAAAT
CAACCCTATGTTTATGGTGATTATTCTATTTTCCTAGCTGAAATTGCATCAACAACAAATGAAAATATATTAACAGAAAC
CCTTTTGAAAGAAGTTAAAGATGATAAAAATCGCTTTGCAATTCTCAATCATTATTTGGACGGTTTCAAAGGAACAATTT
TTAGGCAAACACAGTTCGCTGAATTCGAACATGCCATTCATGTAGCTGATCAGGAGGGGCAAGTACTAACTAGCGAATAC
TTAAACAATCTTTACGCTGAGCTTAATGAAAAATATTATGGTTTGACTAAAGAAGATAATCATTTTATTCAATATGAATG
GGCAAGAATTCCACACTTTTACTACAATTATTATGTTTTCCAATATGCAACCGGCTTCGCAGCAGCAAATTATTTAGCAG
AGCGTATTGTAAACGGTAATCCGGAGGATAAAGAGGCCTACCTAAATTACCTTAAAGCTGGGAATTCAGATTACCCTCTA
AACGTCATTGCTAAAGCTGGTGTTGATATGACTAGTGCAGACTATCTGGATGCAGCTTTTAGAGTATTTGAAGAGCGTTT
AGTGGAACTGGAAAATCTTGTAGCAAAAGGCGTCCATAATGATTAA

Domains

Predicted by InterproScan.

Oligopeptidase F (Peptidase_M3_N)

(112-181)

Peptidase family M3 (Peptidase_M3)

(202-581)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E1ELA1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pepF Streptococcus salivarius strain HSISS4

71.452

99.667

0.712

Multiple sequence alignment