Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   EGX72_RS05570 Genome accession   NZ_CP033809
Coordinates   1014425..1015651 (+) Length   408 a.a.
NCBI ID   WP_000918415.1    Uniprot ID   A0A0H1T4M5
Organism   Streptococcus sp. FDAARGOS_521     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1009425..1020651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX72_RS05540 (EGX72_05535) - 1009642..1010091 (-) 450 WP_123957734.1 DUF1836 domain-containing protein -
  EGX72_RS05545 (EGX72_05540) - 1010183..1011466 (-) 1284 WP_123957735.1 hydroxymethylglutaryl-CoA reductase, degradative -
  EGX72_RS05550 (EGX72_05545) - 1011468..1012640 (-) 1173 WP_001874012.1 hydroxymethylglutaryl-CoA synthase -
  EGX72_RS05555 (EGX72_05550) - 1012794..1013633 (+) 840 WP_000158595.1 thymidylate synthase -
  EGX72_RS05560 (EGX72_05555) - 1013713..1014207 (+) 495 WP_000166043.1 dihydrofolate reductase -
  EGX72_RS05570 (EGX72_05565) clpX 1014425..1015651 (+) 1227 WP_000918415.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  EGX72_RS05575 (EGX72_05570) yihA 1015662..1016258 (+) 597 WP_000796925.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  EGX72_RS05580 (EGX72_05575) - 1016320..1016868 (-) 549 WP_123957736.1 TetR/AcrR family transcriptional regulator -
  EGX72_RS05590 (EGX72_05585) - 1016960..1017463 (+) 504 WP_253257052.1 HXXEE domain-containing protein -
  EGX72_RS05595 (EGX72_05590) - 1017621..1018271 (+) 651 WP_000120095.1 HXXEE domain-containing protein -
  EGX72_RS05600 (EGX72_05595) - 1018401..1019777 (+) 1377 WP_000427485.1 amino acid permease -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 44836.25 Da        Isoelectric Point: 4.4424

>NTDB_id=325874 EGX72_RS05570 WP_000918415.1 1014425..1015651(+) (clpX) [Streptococcus sp. FDAARGOS_521]
MAGNRNNDMNVYCSFCGKSQDEVKKIIAGNGVFICNECVALSQEIIKEELAEEVLADLAEVPKPKELLEILNQYVVGQDR
AKRALAVAVYNHYKRVSYTESSDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENIL
LKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQINTKN
ILFIVGGAFDGIEDLVKQRLGEKVIGFGQTSRKIDDNASYMQEIISEDIQKFGLIPEFIGRLPVVAALELLTAEDLVRIL
TEPRNALVKQYQTLLSYDGVELEFDQDALLAIADKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEGT
DKPVLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=325874 EGX72_RS05570 WP_000918415.1 1014425..1015651(+) (clpX) [Streptococcus sp. FDAARGOS_521]
ATGGCTGGGAATCGTAATAACGATATGAATGTCTATTGTTCATTTTGTGGCAAAAGCCAAGATGAAGTAAAAAAAATTAT
TGCAGGTAATGGTGTTTTCATTTGTAATGAATGTGTGGCCTTATCACAAGAAATTATTAAGGAAGAATTAGCTGAGGAAG
TACTGGCTGATTTAGCAGAAGTACCAAAACCTAAGGAACTATTAGAAATATTAAATCAATATGTTGTAGGGCAAGATCGT
GCTAAACGTGCTTTAGCAGTTGCTGTCTACAATCATTACAAGCGTGTTAGTTATACCGAGAGTAGTGACGATGATGTAGA
TTTGCAAAAATCCAACATTTTGATGATTGGTCCAACTGGCTCAGGAAAAACCTTCTTAGCACAAACACTGGCTAAAAGCC
TTAATGTACCGTTTGCTATTGCAGATGCGACTTCATTGACCGAAGCAGGATACGTTGGAGAAGATGTTGAGAATATTCTT
CTTAAATTGATTCAAGCTGCTGATTATAATGTCGAACGTGCTGAGCGTGGTATTATCTACGTTGATGAAATAGATAAAAT
TGCTAAGAAAGGCGAAAATGTTTCTATCACACGTGATGTGTCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTATTG
AGGGTACGGTAGCAAGTGTTCCCCCACAGGGTGGGCGTAAACATCCTAACCAAGAAATGATTCAAATTAATACCAAGAAC
ATCCTTTTTATTGTCGGTGGTGCTTTTGATGGTATTGAAGACCTTGTGAAGCAACGTTTAGGCGAAAAAGTTATTGGTTT
TGGACAGACAAGCCGTAAAATTGATGACAACGCTTCTTATATGCAAGAGATAATTTCTGAGGATATTCAAAAGTTTGGAC
TGATTCCAGAGTTTATTGGCCGTTTACCAGTAGTTGCAGCGTTAGAACTTCTTACTGCAGAAGATCTGGTTCGTATTCTG
ACAGAACCACGCAATGCTTTGGTTAAACAATACCAAACCTTATTATCTTATGATGGTGTAGAATTGGAATTTGACCAGGA
TGCTCTATTGGCTATCGCTGATAAGGCTATCGAGCGCAAGACTGGTGCACGTGGTTTACGTTCTATTATTGAAGAAACGA
TGCTTGATATCATGTTTGAAATTCCAAGCCAAGAAGATGTAACAAAAGTTCGTATCACAAAGGCTGCTGTTGAGGGTACT
GACAAGCCTGTTTTAGAGACGGCTTAG

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-390)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H1T4M5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

90.465

100

0.907
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.25

98.039

0.571

Multiple sequence alignment