Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   EGX70_RS03860 Genome accession   NZ_CP033808
Coordinates   788076..789425 (-) Length   449 a.a.
NCBI ID   WP_001065469.1    Uniprot ID   R4ZB13
Organism   Streptococcus sp. FDAARGOS_522     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 783076..794425
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EGX70_RS03845 (EGX70_03845) rnc 786030..786716 (-) 687 WP_000661526.1 ribonuclease III -
  EGX70_RS03850 (EGX70_03850) - 786892..787260 (-) 369 WP_000719384.1 YbaN family protein -
  EGX70_RS03855 (EGX70_03855) vicX 787263..788072 (-) 810 WP_001289499.1 MBL fold metallo-hydrolase Regulator
  EGX70_RS03860 (EGX70_03860) vicK 788076..789425 (-) 1350 WP_001065469.1 cell wall metabolism sensor histidine kinase VicK Regulator
  EGX70_RS03865 (EGX70_03865) vicR 789418..790128 (-) 711 WP_000722052.1 response regulator YycF Regulator
  EGX70_RS03870 (EGX70_03870) - 790468..791223 (+) 756 WP_000053154.1 amino acid ABC transporter ATP-binding protein -
  EGX70_RS03875 (EGX70_03875) - 791235..792035 (+) 801 WP_000946171.1 transporter substrate-binding domain-containing protein -
  EGX70_RS03880 (EGX70_03880) - 792048..792743 (+) 696 WP_000173640.1 amino acid ABC transporter permease -
  EGX70_RS03885 (EGX70_03885) - 792755..793405 (+) 651 WP_000100034.1 amino acid ABC transporter permease -
  EGX70_RS03890 (EGX70_03890) - 793454..794020 (-) 567 WP_123947941.1 PepSY domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51059.13 Da        Isoelectric Point: 4.8621

>NTDB_id=325820 EGX70_RS03860 WP_001065469.1 788076..789425(-) (vicK) [Streptococcus sp. FDAARGOS_522]
MNNSAANIRSFELALLFLLVFVAVYFVYLAVRDFKMSKNIRLLNWKVRDLIAGNYSDSILIQGDADLVELGESLNDLSDV
FRMAHDNLEQEKNRLASILTYMTDGVLATDRSGKIVMINETAQQQFNLAYDEALSMNIVDMLGSGSPYSFQDLVSKTPEV
VLNRRDENGEFVTLRIRFALNRRESGFISGLVAVSHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALNE
EVAPSFIKVSLDETNRMMRMISDLLSLSRIDNEVTHLDVEMTNFTAFMTSILNRFDQIRNQKTVTGKVYEIVRDYPLKSI
WVEIDTDKMTQVIDNILNNAVKYSPDGGKITVNLRTTKTQMILSISDQGLGIPKKDLPLIFDRFYRVDKARSRQQGGTGL
GLSIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAVTYEEWEDVED

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=325820 EGX70_RS03860 WP_001065469.1 788076..789425(-) (vicK) [Streptococcus sp. FDAARGOS_522]
ATGAATAATAGTGCTGCAAATATTAGGTCGTTTGAGCTAGCCTTACTTTTTTTACTAGTTTTTGTTGCTGTCTATTTTGT
TTATCTAGCGGTTAGAGATTTTAAAATGTCTAAAAATATCCGGCTTTTGAATTGGAAAGTCAGAGATTTGATAGCAGGAA
ATTATTCAGATAGTATTCTAATTCAAGGTGATGCAGATTTGGTAGAATTAGGGGAAAGTCTAAATGATTTATCTGATGTC
TTCCGAATGGCACATGATAACTTAGAACAAGAAAAGAATCGCTTAGCAAGTATCTTAACTTATATGACTGACGGTGTGCT
GGCTACAGATCGTTCAGGAAAAATCGTTATGATTAATGAGACAGCCCAACAGCAGTTCAATCTAGCATATGATGAAGCTT
TATCAATGAATATTGTTGATATGTTAGGGTCGGGAAGTCCATATTCGTTCCAAGATTTAGTCTCTAAAACGCCAGAGGTA
GTTCTTAATAGACGTGATGAAAATGGTGAATTTGTTACCTTACGGATTCGATTTGCTTTGAACCGTCGTGAAAGTGGTTT
TATTTCCGGTTTAGTTGCAGTATCACACGATGCTACTGAGCAAGAGAAAGAAGAGCGTGAAAGAAGACTTTTTGTATCTA
ATGTTTCTCATGAACTTCGTACACCTTTGACATCTGTAAAATCTTATTTAGAAGCTTTAGATGAGGGAGCGCTCAATGAA
GAAGTTGCTCCAAGCTTCATTAAGGTATCTCTAGATGAAACAAATCGTATGATGCGTATGATATCAGATTTATTAAGTTT
ATCGCGCATTGATAATGAAGTAACGCATTTAGATGTTGAAATGACGAATTTTACAGCTTTCATGACCTCAATTTTGAATC
GATTTGACCAGATTAGAAATCAAAAAACAGTCACAGGAAAAGTTTATGAAATTGTCAGAGATTATCCTCTTAAGTCAATT
TGGGTGGAAATTGATACAGATAAAATGACTCAAGTGATTGATAACATTTTAAATAATGCAGTCAAGTATTCACCAGATGG
TGGTAAGATTACAGTTAATCTACGCACAACTAAAACGCAGATGATTTTATCAATATCAGACCAAGGCTTAGGTATTCCCA
AAAAAGATTTACCTCTCATCTTTGATCGTTTTTATCGTGTTGATAAGGCGAGAAGTCGTCAACAGGGTGGGACTGGACTT
GGTTTGTCAATTGCAAAAGAAATTGTTAAGCAGCATAAGGGATTTATTTGGGCTAAGAGTGAGTATGGTAAAGGGTCTAC
TTTTACAATCGTCTTGCCTTATGATAAAGATGCTGTAACTTATGAAGAATGGGAGGACGTTGAAGATTAA

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

PAS fold (PAS)

(94-180)

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB R4ZB13

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.576

91.982

0.686
  micB Streptococcus pneumoniae Cp1015

67.436

96.437

0.65

Multiple sequence alignment