Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FK544_RS10985 Genome accession   NZ_CP041304
Coordinates   2064390..2065046 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MSHS 133     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2059390..2070046
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FK544_RS10950 (FK544_10940) dcyD 2060270..2061256 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  FK544_RS10955 (FK544_10945) tcyL 2061271..2061939 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FK544_RS10960 (FK544_10950) tcyN 2061936..2062688 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FK544_RS10965 (FK544_10955) sdiA 2062918..2063640 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  FK544_RS10970 (FK544_10960) yecF 2063707..2063931 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FK544_RS10975 (FK544_10965) yecU 2063918..2064094 (-) 177 WP_000590344.1 protein YecU -
  FK544_RS26300 (FK544_10970) - 2064132..2064248 (-) 117 WP_001302039.1 hypothetical protein -
  FK544_RS10985 (FK544_10975) letA 2064390..2065046 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FK544_RS10990 (FK544_10980) uvrC 2065043..2066875 (+) 1833 WP_001283427.1 excinuclease ABC subunit UvrC Machinery gene
  FK544_RS10995 (FK544_10985) pgsA 2066932..2067480 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FK544_RS11015 (FK544_11005) - 2068476..2068757 (+) 282 WP_071589622.1 hypothetical protein -
  FK544_RS11020 (FK544_11010) - 2068949..2069089 (-) 141 WP_000078920.1 Hok/Gef family protein -
  FK544_RS11025 (FK544_11015) - 2069280..2069540 (-) 261 WP_000488113.1 ogr/Delta-like zinc finger family protein -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=325378 FK544_RS10985 WP_000611335.1 2064390..2065046(+) (letA) [Escherichia coli strain MSHS 133]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=325378 FK544_RS10985 WP_000611335.1 2064390..2065046(+) (letA) [Escherichia coli strain MSHS 133]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486