Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FK541_RS11295 Genome accession   NZ_CP041300
Coordinates   2144918..2145574 (+) Length   218 a.a.
NCBI ID   WP_022645829.1    Uniprot ID   -
Organism   Escherichia coli O1:H42 strain CLSC36     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2139918..2150574
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FK541_RS11265 (FK541_11265) dcyD 2140798..2141784 (+) 987 WP_001128235.1 D-cysteine desulfhydrase -
  FK541_RS11270 (FK541_11270) tcyL 2141799..2142467 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FK541_RS11275 (FK541_11275) tcyN 2142464..2143216 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FK541_RS11280 (FK541_11280) sdiA 2143446..2144168 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  FK541_RS11285 (FK541_11285) yecF 2144235..2144459 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FK541_RS11290 (FK541_11290) yecU 2144446..2144622 (-) 177 WP_001307856.1 protein YecU -
  FK541_RS11295 (FK541_11295) letA 2144918..2145574 (+) 657 WP_022645829.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FK541_RS11300 (FK541_11300) uvrC 2145571..2147403 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FK541_RS11305 (FK541_11305) pgsA 2147460..2148008 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FK541_RS11325 (FK541_11325) - 2148706..2149358 (-) 653 Protein_1978 hypothetical protein -
  FK541_RS11330 (FK541_11330) - 2149420..2150508 (+) 1089 Protein_1979 IS3 family transposase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23938.73 Da        Isoelectric Point: 6.9612

>NTDB_id=325220 FK541_RS11295 WP_022645829.1 2144918..2145574(+) (letA) [Escherichia coli O1:H42 strain CLSC36]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIAYDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=325220 FK541_RS11295 WP_022645829.1 2144918..2145574(+) (letA) [Escherichia coli O1:H42 strain CLSC36]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACTGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTATGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482