Detailed information NTG0325029

Bioinformatically predicted

Overview

• Name: clpC
• Type: Regulator
• Locus tag: FKM99_RS11540
• Genome accession: NZ_CP041202
• Coordinates: 593595..596168 (+)
• Length: 857 a.a.
• NCBI ID: WP_005460310.1
• Uniprot ID: Q87S63
• Organism: Vibrio parahaemolyticus strain Vb0624
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 588595..601168

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
FKM99_RS11515 (FKM99_11515)	hpf	588602..588928 (-)	327	WP_005468590.1	ribosome hibernation-promoting factor, HPF/YfiA family	-
FKM99_RS11520 (FKM99_11520)	-	589259..590740 (-)	1482	WP_323243679.1	lytic transglycosylase F	-
FKM99_RS11525 (FKM99_11525)	comL	590875..591603 (-)	729	WP_005460312.1	outer membrane protein assembly factor BamD	Machinery gene
FKM99_RS11530 (FKM99_11530)	rluD	591740..592717 (+)	978	WP_005460300.1	23S rRNA pseudouridine(1911/1915/1917) synthase RluD	-
FKM99_RS11535 (FKM99_11535)	pgeF	592719..593447 (+)	729	WP_025518860.1	peptidoglycan editing factor PgeF	-
FKM99_RS11540 (FKM99_11540)	clpC	593595..596168 (+)	2574	WP_005460310.1	ATP-dependent chaperone ClpB	Regulator

Sequence

Protein

• Length: 857 a.a.
• Molecular weight: 95872.46 Da
• Isoelectric Point: 5.1096

>NTDB_id=325029 FKM99_RS11540 WP_005460310.1 593595..596168(+) (clpC) [Vibrio parahaemolyticus strain Vb0624]
MRLDRFTSKFQIAISDAQSLALGRDHQYIEPVHLMVALLDQNGSPIRPLLTMLDVDVTHLRSKLGEMLDRLPKVSGIGGD
VQLSSSMGTLFNLCDKVAQKRQDSYISSEVFLLAALEDRGPLGQLLKEVGLTEQKVSQAIEKIRGGQKVNDPNAEELRQA
LEKFTIDLTERAEQGKLDPVIGRDDEIRRTIQVLQRRTKNNPVIIGEPGVGKTAIVEGLAQRIVNNEVPEGLRGRRVLSL
DMGALVAGAKYRGEFEERLKSVLNELAKEEGNVILFIDELHTMVGAGKGEGSMDAGNMLKPALARGELHCVGATTLDEYR
QYIEKDAALERRFQKVLVDEPTVEDTVAILRGLKERYELHHHVEITDPAIVAAASLSHRYISDRQLPDKAIDLIDEAASS
IRLQIDSKPESLDKLERKIIQLKIEQQALSNEHDEASEKRLQALNDELNEKEREYAELEEVWNTEKAALSGTQHIKSELE
QARMDMEFARRAGDLNRMSELQYGRIPELEKQLDLATQAEMQEMTLLRNKVTDNEIAEVLSKQTGIPVSKMLEAEKEKLL
RMEDVLHNRVVGQSEAVAVVSNAIRRSRAGLSDPNRPIGSFLFLGPTGVGKTELCKTLASFMFDSEDAMVRIDMSEFMEK
HSVARLVGAPPGYVGYEEGGYLTEAVRRKPYSVILLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GSSRIQENFATLDYQGIKSEVMDVVSKHFRPEFLNRVDEIVVFHPLGQEHIKSIASIQLERLAKRLEEKGYQLEVSDKAL
DLIAQVGFDPVYGARPLKRAIQQNVENPLAKSILAGEIVPDKKVQLIVTNDQILAHQ

Nucleotide

• Length: 2574 bp

>NTDB_id=325029 FKM99_RS11540 WP_005460310.1 593595..596168(+) (clpC) [Vibrio parahaemolyticus strain Vb0624]
ATGCGTCTTGATAGATTTACCAGTAAGTTTCAAATCGCTATCTCTGATGCTCAATCACTAGCGTTAGGGCGCGATCATCA
GTACATCGAGCCAGTTCACTTAATGGTGGCTTTGCTTGATCAAAATGGCAGTCCAATTCGTCCATTGCTGACAATGCTGG
ACGTGGATGTAACTCATCTCCGCTCAAAGCTAGGCGAAATGCTTGATCGATTACCAAAGGTGAGTGGCATCGGTGGTGAT
GTGCAGCTTTCTAGCTCGATGGGGACTTTGTTCAATCTGTGTGACAAAGTGGCTCAAAAGCGTCAAGACTCCTACATCTC
GTCCGAAGTCTTCTTGCTTGCGGCATTAGAAGATCGTGGTCCTTTAGGGCAACTACTCAAAGAAGTTGGGCTGACCGAGC
AAAAAGTGAGTCAAGCGATTGAAAAGATCAGAGGTGGCCAAAAGGTCAATGATCCAAATGCTGAAGAGCTACGTCAGGCT
CTTGAAAAATTCACCATCGATTTAACTGAGCGAGCTGAGCAGGGCAAATTGGATCCTGTAATTGGTCGAGATGATGAAAT
TCGTCGCACGATTCAAGTATTGCAACGTCGCACCAAAAACAACCCAGTGATCATCGGCGAGCCTGGTGTGGGTAAAACCG
CAATTGTGGAAGGCTTGGCGCAGCGAATTGTTAATAACGAAGTGCCAGAAGGTCTACGCGGTCGCCGTGTGTTATCACTG
GATATGGGCGCACTTGTTGCTGGCGCGAAATACCGTGGTGAATTTGAAGAGCGTTTAAAATCAGTATTGAATGAACTTGC
TAAAGAAGAAGGCAACGTCATCCTCTTCATTGATGAACTACACACTATGGTCGGCGCTGGTAAAGGTGAAGGCTCAATGG
ATGCGGGCAACATGCTCAAACCAGCATTGGCTCGCGGCGAACTTCACTGTGTTGGTGCAACAACATTGGATGAGTACCGT
CAATACATCGAAAAGGATGCTGCATTAGAACGTCGTTTCCAAAAAGTGCTGGTGGATGAGCCGACAGTAGAAGATACGGT
GGCTATTCTTCGTGGTCTGAAAGAGCGTTATGAACTTCATCACCATGTAGAAATTACTGACCCAGCGATTGTTGCAGCGG
CAAGTTTGTCGCACCGTTATATTTCGGACCGTCAGTTGCCAGATAAAGCCATTGACTTGATCGATGAAGCGGCTTCAAGC
ATTCGTCTACAAATTGATTCAAAACCAGAATCATTGGATAAGCTTGAGCGTAAAATCATCCAACTAAAAATTGAGCAACA
AGCACTAAGTAACGAGCACGATGAAGCGAGTGAAAAGCGTCTGCAAGCATTGAATGATGAGTTGAATGAGAAAGAACGCG
AATACGCAGAGTTAGAAGAGGTTTGGAATACAGAAAAAGCCGCACTTTCTGGTACTCAGCATATTAAATCTGAACTAGAG
CAAGCTCGCATGGACATGGAGTTTGCGCGTCGTGCTGGTGATCTAAACCGAATGTCTGAGCTTCAATACGGTCGTATTCC
GGAATTAGAGAAGCAACTAGATTTGGCGACTCAGGCTGAAATGCAAGAAATGACGCTGCTTCGTAACAAAGTAACAGATA
ACGAAATCGCAGAAGTGCTTTCTAAACAAACGGGCATTCCAGTATCTAAGATGTTAGAAGCGGAGAAAGAGAAACTACTT
CGCATGGAAGATGTGCTTCACAATCGTGTTGTAGGGCAAAGCGAAGCAGTTGCAGTGGTATCGAACGCGATTCGTCGTAG
CCGAGCTGGGCTTTCTGATCCAAACCGACCAATTGGTTCCTTCTTATTCTTAGGCCCAACTGGTGTCGGTAAAACGGAAC
TATGTAAGACACTCGCGAGCTTCATGTTCGACAGTGAAGATGCAATGGTACGCATCGATATGTCGGAGTTCATGGAGAAA
CACTCAGTGGCAAGATTAGTGGGTGCGCCTCCAGGTTACGTTGGTTACGAAGAGGGTGGTTATCTAACTGAAGCGGTTCG
TCGTAAACCATACTCAGTGATCTTGTTGGATGAAGTAGAAAAAGCACATCCAGATGTGTTCAATATTCTTCTGCAGGTGC
TTGATGATGGCCGACTCACAGATGGACAAGGTCGTACGGTTGATTTTCGTAACACCGTCGTGATCATGACATCAAACTTG
GGTTCCTCTCGAATCCAAGAGAACTTCGCCACATTGGACTATCAAGGTATCAAGAGTGAAGTGATGGATGTGGTTAGCAA
ACACTTCCGCCCAGAGTTCTTGAACCGTGTTGACGAAATAGTGGTATTCCACCCACTTGGTCAAGAGCACATTAAGTCCA
TTGCTTCTATTCAATTAGAACGCTTGGCAAAACGACTAGAAGAAAAAGGGTATCAATTGGAGGTGTCTGATAAAGCACTC
GACTTGATCGCCCAAGTCGGTTTCGACCCAGTATACGGTGCACGTCCTTTAAAACGTGCAATTCAACAGAATGTCGAGAA
CCCATTAGCTAAATCCATTCTTGCTGGTGAAATAGTTCCAGACAAGAAAGTGCAGCTAATCGTTACTAATGACCAAATTC
TCGCTCATCAGTAA

Domains

Predicted by InterProScan.

• AAA lid domain (AAA_lid_9) (342-444)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (17-68)

• Clp amino terminal domain, pathogenicity island component (Clp_N) (94-145)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (766-845)

• AAA domain (Cdc48 subfamily) (AAA_2) (596-760)

• ATPase family associated with various cellular activities (AAA) (AAA) (204-320)

3D structure

• AlphaFold DB: Q87S63

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpC	Bacillus subtilis subsp. subtilis str. 168	46.597	100	0.471
clpE	Streptococcus mutans UA159	49.115	79.113	0.389
clpE	Streptococcus pneumoniae Rx1	47.701	81.214	0.387
clpE	Streptococcus pneumoniae D39	47.701	81.214	0.387
clpE	Streptococcus pneumoniae R6	47.701	81.214	0.387
clpC	Lactococcus lactis subsp. cremoris KW2	46.965	80.747	0.379