Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BLCSL_RS18105 Genome accession   NZ_CP041154
Coordinates   3430831..3431466 (-) Length   211 a.a.
NCBI ID   WP_003185124.1    Uniprot ID   Q65F45
Organism   Bacillus licheniformis strain CSL2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3425831..3436466
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BLCSL_RS18080 (BLCSL_18080) - 3426447..3426614 (-) 168 WP_003185114.1 YvzF family protein -
  BLCSL_RS18085 (BLCSL_18085) - 3426738..3428180 (+) 1443 WP_025807513.1 spore germination protein -
  BLCSL_RS18090 (BLCSL_18090) - 3428149..3429249 (+) 1101 WP_025807515.1 endospore germination permease -
  BLCSL_RS18095 (BLCSL_18095) - 3429246..3430367 (+) 1122 WP_003185120.1 Ger(x)C family spore germination protein -
  BLCSL_RS18100 (BLCSL_18100) - 3430411..3430794 (+) 384 WP_003185122.1 hypothetical protein -
  BLCSL_RS18105 (BLCSL_18105) vraR 3430831..3431466 (-) 636 WP_003185124.1 response regulator transcription factor Regulator
  BLCSL_RS18110 (BLCSL_18110) liaS 3431470..3432534 (-) 1065 WP_075178260.1 two-component system sensor histidine kinase LiaS -
  BLCSL_RS18115 (BLCSL_18115) liaF 3432531..3433262 (-) 732 WP_003185130.1 cell wall-active antibiotics response protein LiaF -
  BLCSL_RS18120 (BLCSL_18120) - 3433293..3434156 (-) 864 WP_140991830.1 DUF4097 domain-containing protein -
  BLCSL_RS18125 (BLCSL_18125) liaH 3434262..3434945 (-) 684 WP_009329563.1 stress responsive protein LiaH -
  BLCSL_RS18130 (BLCSL_18130) - 3434966..3435352 (-) 387 WP_003185133.1 protein liaI -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23095.83 Da        Isoelectric Point: 5.1797

>NTDB_id=324989 BLCSL_RS18105 WP_003185124.1 3430831..3431466(-) (vraR) [Bacillus licheniformis strain CSL2]
MIRVLLIDDHEMVRMGLAAFLESQPDIEVIGEASDGKRGVELALETKPDVILMDLVMEGMDGIEATKQICRQLADPKIIV
LTSFVDDDKVYPVIEAGALSYLLKTSKASEIADAIRAASVGEPKLEAKVAGKVLSKLRHSAGEQPLHQSLTARELEILKL
VAEGKTNKGIAEELYITIKTVKTHVTNILSKLEVDDRTQAAIYAHRNKLVD

Nucleotide


Download         Length: 636 bp        

>NTDB_id=324989 BLCSL_RS18105 WP_003185124.1 3430831..3431466(-) (vraR) [Bacillus licheniformis strain CSL2]
GTGATTCGAGTATTGTTAATTGATGATCATGAAATGGTGAGAATGGGGCTGGCCGCTTTCCTGGAATCCCAGCCTGATAT
TGAAGTGATTGGGGAGGCATCAGACGGAAAGCGCGGCGTTGAATTGGCGCTTGAAACCAAACCCGACGTGATTTTGATGG
ATCTTGTGATGGAAGGGATGGACGGAATTGAGGCCACGAAACAAATATGCCGGCAGCTTGCCGATCCGAAAATCATCGTT
CTGACGAGCTTCGTTGATGATGACAAGGTCTATCCGGTCATCGAAGCCGGAGCGCTCAGCTATTTGCTGAAAACGTCGAA
AGCGAGTGAAATCGCCGATGCGATCAGGGCTGCGAGCGTCGGAGAACCAAAGCTTGAAGCCAAAGTCGCAGGAAAAGTGT
TGTCCAAGCTGAGACATTCAGCCGGCGAACAGCCCCTTCATCAATCGCTGACGGCAAGAGAATTGGAAATCCTCAAACTT
GTAGCAGAGGGCAAGACAAACAAAGGTATTGCCGAAGAATTATATATCACCATTAAAACAGTTAAAACGCATGTGACGAA
CATCCTTTCCAAGCTTGAAGTCGACGACCGGACACAAGCCGCAATCTACGCCCACCGAAACAAACTTGTCGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(148-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q65F45

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

53.11

99.052

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

36.444

100

0.389