Detailed information NTG0324481

Bioinformatically predicted

Overview

• Name: clpX
• Type: Regulator
• Locus tag: EGC57_RS03555
• Genome accession: NZ_CP033621
• Coordinates: 683053..684282 (+)
• Length: 409 a.a.
• NCBI ID: WP_129328315.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain M75
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 678053..689282

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
EGC57_RS03530 (EGC57_03540)	-	678669..679946 (-)	1278	WP_002984963.1	hydroxymethylglutaryl-CoA reductase, degradative	-
EGC57_RS03535 (EGC57_03545)	-	679933..681108 (-)	1176	WP_021299369.1	hydroxymethylglutaryl-CoA synthase	-
EGC57_RS03540 (EGC57_03550)	-	681317..682156 (+)	840	WP_011017679.1	thymidylate synthase	-
EGC57_RS03545 (EGC57_03555)	-	682236..682733 (+)	498	WP_002984955.1	dihydrofolate reductase	-
EGC57_RS03550 (EGC57_03560)	-	682753..682923 (+)	171	WP_002990165.1	hypothetical protein	-
EGC57_RS03555 (EGC57_03565)	clpX	683053..684282 (+)	1230	WP_129328315.1	ATP-dependent Clp protease ATP-binding subunit ClpX	Regulator
EGC57_RS03560 (EGC57_03570)	yihA	684292..684891 (+)	600	WP_076639697.1	ribosome biogenesis GTP-binding protein YihA/YsxC	-
EGC57_RS03565 (EGC57_03575)	-	685039..685782 (+)	744	WP_002984942.1	hypothetical protein	-
EGC57_RS03570 (EGC57_03580)	-	685840..687939 (-)	2100	WP_076639696.1	ATP-dependent Clp protease ATP-binding subunit	-
EGC57_RS03575 (EGC57_03585)	rpiA	688317..689000 (+)	684	WP_002984936.1	ribose-5-phosphate isomerase RpiA	-

Sequence

Protein

• Length: 409 a.a.
• Molecular weight: 44991.44 Da
• Isoelectric Point: 4.5775

>NTDB_id=324481 EGC57_RS03555 WP_129328315.1 683053..684282(+) (clpX) [Streptococcus pyogenes strain M75]
MAGSRTNDIKVYCSFCGKSQDDVKKIIAGNNVFICNECVALSQEIIKEELAEEVLADLTEVPKPKELLDVLNQYVVGQDR
AKRALSVAVYNHYKRVSFTESRDDDDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATSLTEAGYVGEDVENI
LLKLIQAADYNVERAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIQIDTK
NILFIVGGAFDGIEEIVKQRLGEKVIGFGQNSRKIDDNASYMQEIISEDIQKFGIIPEFIGRLPVVAALEQLNTSDLIQI
LTEPRNALVKQYQALLSYDGVELAFDKEALEAIANKAIERKTGARGLRSIIEETMLDIMFEIPSQEDVTKVRITKAAVEG
KSKPVLETA

Nucleotide

• Length: 1230 bp

>NTDB_id=324481 EGC57_RS03555 WP_129328315.1 683053..684282(+) (clpX) [Streptococcus pyogenes strain M75]
ATGGCAGGAAGTAGAACTAACGATATTAAAGTATACTGTTCATTTTGTGGTAAAAGCCAGGATGACGTTAAAAAAATTAT
CGCAGGAAATAATGTTTTCATCTGCAATGAATGCGTAGCTTTATCACAAGAAATTATAAAAGAAGAATTGGCTGAAGAAG
TCCTTGCCGATTTGACAGAAGTTCCAAAACCAAAAGAGCTTCTTGATGTTTTAAATCAATATGTGGTTGGTCAAGATCGT
GCTAAACGTGCTTTATCAGTTGCTGTGTACAATCATTATAAGCGTGTCTCGTTTACAGAAAGTCGTGATGACGATGATGT
GGATTTACAAAAGTCCAACATTTTGATGATTGGACCAACAGGTTCAGGAAAAACCTTCTTAGCACAAACTCTGGCTAAAA
GCCTCAATGTACCATTTGCTATTGCAGATGCAACTTCTTTGACTGAAGCAGGGTATGTTGGAGAAGATGTGGAAAATATT
TTACTCAAACTGATTCAGGCTGCTGACTATAATGTCGAACGAGCAGAGCGTGGTATTATTTATGTTGATGAAATAGATAA
GATTGCTAAAAAAGGTGAGAACGTATCTATCACACGTGATGTATCTGGTGAAGGTGTACAGCAAGCCCTTCTTAAAATTA
TTGAAGGTACGGTAGCAAGTGTTCCCCCACAAGGTGGGCGGAAGCATCCTAATCAAGAAATGATCCAAATTGATACAAAA
AATATCTTGTTTATTGTTGGCGGGGCTTTTGATGGCATCGAGGAGATTGTTAAACAACGTTTAGGTGAAAAAGTTATTGG
TTTTGGTCAAAACAGCCGTAAAATTGATGACAATGCTTCTTATATGCAAGAAATTATTTCAGAAGATATTCAAAAGTTTG
GGATTATTCCAGAATTTATTGGCCGCTTACCAGTTGTGGCAGCCCTTGAACAACTAAACACATCAGATTTGATTCAAATT
TTGACAGAACCAAGAAATGCCCTGGTCAAGCAATATCAGGCCCTTCTTTCTTACGATGGCGTCGAATTGGCATTTGATAA
GGAAGCCTTAGAAGCCATTGCCAATAAAGCCATTGAACGTAAGACAGGAGCACGTGGTCTTCGTTCTATTATTGAAGAAA
CGATGTTAGACATTATGTTTGAAATTCCAAGCCAAGAAGATGTCACAAAAGTGCGTATCACCAAGGCTGCTGTCGAAGGC
AAGTCAAAACCCGTTTTAGAGACAGCTTAA

Domains

Predicted by InterproScan.

• AAA domain (Cdc48 subfamily) (AAA_2) (110-305)

• C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small) (312-391)

• ClpX C4-type zinc finger (zf-C4_ClpX) (12-48)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpX	Streptococcus mutans UA159	88.753	100	0.888
clpX	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.354	98.044	0.572