Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   SMUNN2025_RS07610 Genome accession   NC_013928
Coordinates   1566333..1566974 (-) Length   213 a.a.
NCBI ID   WP_002263036.1    Uniprot ID   -
Organism   Streptococcus mutans NN2025     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1561333..1571974
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUNN2025_RS07590 (SmuNN2025_1480) - 1562773..1563519 (-) 747 WP_002277409.1 DeoR/GlpR family DNA-binding transcription regulator -
  SMUNN2025_RS07595 (SmuNN2025_1481) - 1563650..1564426 (+) 777 WP_002277408.1 glycyl-radical enzyme activating protein -
  SMUNN2025_RS07600 (SmuNN2025_1482) - 1564504..1564890 (-) 387 WP_002268943.1 S1 RNA-binding domain-containing protein -
  SMUNN2025_RS07605 (SmuNN2025_1483) - 1564874..1566289 (-) 1416 WP_012997902.1 Cof-type HAD-IIB family hydrolase -
  SMUNN2025_RS07610 (SmuNN2025_1484) vraR 1566333..1566974 (-) 642 WP_002263036.1 response regulator transcription factor Regulator
  SMUNN2025_RS07615 (SmuNN2025_1485) - 1566967..1567971 (-) 1005 WP_002263037.1 sensor histidine kinase -
  SMUNN2025_RS07620 (SmuNN2025_1486) liaF 1567968..1568663 (-) 696 WP_002263038.1 cell wall-active antibiotics response protein LiaF -
  SMUNN2025_RS07625 (SmuNN2025_1487) pknB 1569104..1570954 (-) 1851 WP_002263039.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  SMUNN2025_RS07630 (SmuNN2025_1488) - 1570951..1571694 (-) 744 WP_002263040.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23824.40 Da        Isoelectric Point: 4.8864

>NTDB_id=32444 SMUNN2025_RS07610 WP_002263036.1 1566333..1566974(-) (vraR) [Streptococcus mutans NN2025]
MSKTKVILVDDHEMVRLGLKSFLNLQDNVEVIGEASNGRQGIDLALKLKPDVVVMDLVMPEMDGVEATLELLKDWKEAKI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIQKVAKGDLAIETEVDKKIKDHHNNPDLHEDLTARERDILALLA
KGYDNQTIADELFISLKTVKTHVSNILSKLQVDDRTQAVVYAFQHHLVPQDEN

Nucleotide


Download         Length: 642 bp        

>NTDB_id=32444 SMUNN2025_RS07610 WP_002263036.1 1566333..1566974(-) (vraR) [Streptococcus mutans NN2025]
ATGAGTAAAACAAAAGTTATACTGGTTGATGATCATGAAATGGTTCGATTGGGTTTGAAAAGTTTTCTTAATTTACAAGA
TAATGTAGAAGTTATCGGTGAGGCTAGCAATGGCCGTCAAGGTATTGACTTGGCTTTAAAATTAAAACCAGACGTTGTTG
TCATGGACTTGGTTATGCCAGAAATGGATGGTGTAGAAGCCACTCTTGAACTTCTAAAAGATTGGAAAGAAGCCAAAATT
CTAGTTTTAACCAGTTATTTAGATAACGAAAAAATTTATCCTGTCATTGAAGCAGGTGCTAAAGGTTATATGTTGAAAAC
TTCCAGCGCAGCTGAAATTTTGAATGCCATTCAAAAAGTAGCTAAGGGAGATTTAGCGATTGAAACAGAAGTTGATAAGA
AAATCAAGGATCATCATAATAATCCTGATTTGCATGAAGATTTAACAGCGCGTGAACGAGACATTTTGGCTTTACTTGCT
AAGGGTTATGATAACCAAACGATTGCTGATGAGCTTTTCATTTCTTTGAAGACTGTCAAAACACATGTTTCTAATATCTT
ATCGAAATTACAAGTTGATGATCGGACCCAAGCCGTTGTCTATGCTTTTCAGCATCATTTAGTGCCACAGGACGAAAATT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.22

96.244

0.493
  degU Bacillus subtilis subsp. subtilis str. 168

35.398

100

0.376

Multiple sequence alignment