Detailed information    

insolico Bioinformatically predicted

Overview

Name   mecA   Type   Regulator
Locus tag   EFD52_RS08330 Genome accession   NZ_CP033606
Coordinates   1710743..1711444 (-) Length   233 a.a.
NCBI ID   WP_004255173.1    Uniprot ID   S6FFV7
Organism   Lactococcus lactis strain IL6288     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1705743..1716444
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  EFD52_RS08310 (EFD52_08310) - 1705853..1707070 (-) 1218 WP_004255189.1 cysteine desulfurase -
  EFD52_RS08315 (EFD52_08315) sufD 1707070..1708326 (-) 1257 WP_010906140.1 Fe-S cluster assembly protein SufD -
  EFD52_RS08320 (EFD52_08320) sufC 1708464..1709234 (-) 771 WP_004255181.1 Fe-S cluster assembly ATPase SufC -
  EFD52_RS08325 (EFD52_08325) - 1709409..1710740 (-) 1332 WP_010906141.1 MraY family glycosyltransferase -
  EFD52_RS08330 (EFD52_08330) mecA 1710743..1711444 (-) 702 WP_004255173.1 adaptor protein MecA Regulator
  EFD52_RS08335 (EFD52_08335) - 1711574..1712308 (-) 735 WP_004255171.1 amino acid ABC transporter ATP-binding protein -
  EFD52_RS08340 (EFD52_08340) - 1712308..1712994 (-) 687 WP_004255158.1 amino acid ABC transporter permease -
  EFD52_RS08345 (EFD52_08345) - 1713142..1714050 (-) 909 WP_003130548.1 diacylglycerol kinase family protein -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 27077.46 Da        Isoelectric Point: 4.1246

>NTDB_id=324329 EFD52_RS08330 WP_004255173.1 1710743..1711444(-) (mecA) [Lactococcus lactis strain IL6288]
MKYEDINENTIKITLSFDDLTDYDIKLSDFFGNQEVIEQFFYELVDELGLENRFGNVGMLTFQIQPFPQGVHMIVHEEAM
LGEGGEIPDDPEEFEELMTGFYNKLNEIGADMARERGITDFKPGLGLPGTKKDEAEQEPDFIYYSIRYEDIMSVLTGIKN
VKFADEESEFYRYDGNFYLVVLDNQKEKGKMHVESTRSRMMEYGEATKMSREFLQEYGECLIATRALDVLRKI

Nucleotide


Download         Length: 702 bp        

>NTDB_id=324329 EFD52_RS08330 WP_004255173.1 1710743..1711444(-) (mecA) [Lactococcus lactis strain IL6288]
ATGAAATATGAGGATATAAACGAAAATACTATAAAAATCACCTTGTCTTTTGATGATTTGACAGATTATGATATCAAATT
ATCAGACTTTTTCGGAAATCAAGAAGTCATTGAACAATTTTTCTATGAATTGGTTGATGAGCTTGGTTTAGAAAATCGCT
TTGGAAATGTGGGAATGTTAACTTTCCAAATCCAACCTTTTCCTCAAGGTGTTCATATGATTGTTCATGAAGAAGCGATG
CTAGGTGAAGGTGGAGAAATTCCAGATGACCCAGAAGAGTTTGAAGAATTGATGACTGGTTTTTATAATAAATTAAATGA
AATAGGGGCAGATATGGCGCGCGAGCGAGGAATTACTGATTTTAAACCTGGGCTTGGTTTACCAGGAACAAAAAAAGACG
AAGCTGAACAAGAGCCAGATTTTATTTATTACTCTATTCGTTATGAAGATATTATGTCTGTCTTAACAGGAATAAAAAAT
GTGAAGTTTGCTGATGAAGAATCAGAGTTTTATCGTTATGATGGCAATTTTTATCTTGTTGTTTTGGATAATCAAAAAGA
AAAAGGCAAGATGCATGTCGAAAGTACCCGTTCACGAATGATGGAATATGGGGAAGCAACAAAAATGAGTCGAGAATTTT
TGCAGGAGTATGGTGAATGTCTTATCGCGACACGTGCTTTAGATGTTCTTAGAAAAATCTAA

Domains

Predicted by InterproScan.

Negative regulator of genetic competence (MecA) (MecA)

(1-230)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB S6FFV7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  mecA Lactococcus lactis subsp. lactis strain DGCC12653

99.571

100

0.996
  mecA Lactococcus lactis subsp. cremoris KW2

96.996

100

0.97

Multiple sequence alignment