Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FHY70_RS23015 Genome accession   NZ_CP040886
Coordinates   4361777..4362433 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain K71-77     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4356777..4367433
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FHY70_RS22985 (FHY70_22980) dcyD 4357656..4358642 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  FHY70_RS22990 (FHY70_22985) tcyL 4358657..4359325 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FHY70_RS22995 (FHY70_22990) tcyN 4359322..4360074 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FHY70_RS23000 (FHY70_22995) sdiA 4360304..4361026 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  FHY70_RS23005 (FHY70_23000) yecF 4361094..4361318 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FHY70_RS23010 (FHY70_23005) yecU 4361305..4361481 (-) 177 WP_000590347.1 protein YecU -
  FHY70_RS26605 - 4361564..4361635 (-) 72 Protein_4130 transcriptional regulator -
  FHY70_RS23015 (FHY70_23010) letA 4361777..4362433 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FHY70_RS23020 (FHY70_23015) uvrC 4362430..4364262 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FHY70_RS23025 (FHY70_23020) pgsA 4364319..4364867 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FHY70_RS23045 (FHY70_23040) yecA 4365517..4366182 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=323708 FHY70_RS23015 WP_000611335.1 4361777..4362433(+) (letA) [Escherichia coli strain K71-77]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=323708 FHY70_RS23015 WP_000611335.1 4361777..4362433(+) (letA) [Escherichia coli strain K71-77]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486