Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SMI_RS03285 Genome accession   NC_013853
Coordinates   597701..598378 (+) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus mitis B6     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 592701..603378
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMI_RS03255 (smi_0643) dtd 593239..593682 (+) 444 WP_000691419.1 D-aminoacyl-tRNA deacylase -
  SMI_RS03260 (smi_0644) - 593721..594134 (-) 414 WP_000720033.1 hypothetical protein -
  SMI_RS03265 (smi_0645) - 594298..594948 (-) 651 WP_000188508.1 metal-dependent transcriptional regulator -
  SMI_RS03270 (smi_0646) - 595060..595902 (+) 843 WP_000975512.1 metallophosphoesterase family protein -
  SMI_RS03275 (smi_0647) - 595978..596415 (+) 438 WP_001166793.1 Rrf2 family transcriptional regulator -
  SMI_RS03280 (smi_0648) - 596472..597545 (-) 1074 WP_001273809.1 DUF2974 domain-containing protein -
  SMI_RS03285 (smi_0649) braR 597701..598378 (+) 678 WP_000548991.1 response regulator transcription factor Regulator
  SMI_RS03290 (smi_0650) - 598371..599345 (+) 975 WP_000887976.1 sensor histidine kinase -
  SMI_RS03295 (smi_0651) - 600144..601655 (+) 1512 WP_000938206.1 ATP-binding cassette domain-containing protein -
  SMI_RS03300 (smi_0652) - 601946..602995 (+) 1050 WP_000147505.1 DUF389 domain-containing protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=32281 SMI_RS03285 WP_000548991.1 597701..598378(+) (braR) [Streptococcus mitis B6]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=32281 SMI_RS03285 WP_000548991.1 597701..598378(+) (braR) [Streptococcus mitis B6]
ATGCACAAGATTTTATTAGTAGAGGATGATCAGGTTATTCGTCAACAAGTCGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAGCCTCATCTGGTTCTCATGGATATTG
GACTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTGCCTATCATGTTTCTGTCTTCC
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGCGCGGATGACTTTGTGACCAAGCCTTTTGATCAGCAGGT
TCTTTTAGCCAAAGTTCAGGGCTTGTTACGTCGTTCCTATGAGTTTGGGCGTGACGAGAGTTTACTGGAATATGCCGGTG
TTATCCTCAATACCAAATCAATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTCTTGTTTGAGCATGCAGGCAATATCGTAGCGCGTGATGACCTCATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAAGAGCAGGGCTTGGTAGGATTTATCGAAA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment