Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FGC38_RS10700 Genome accession   NZ_CP040643
Coordinates   2127164..2127820 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain BE104     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2122164..2132820
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FGC38_RS10670 (FGC38_10670) yecA 2123415..2124080 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  FGC38_RS10690 (FGC38_10690) pgsA 2124730..2125278 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FGC38_RS10695 (FGC38_10695) uvrC 2125335..2127167 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FGC38_RS10700 (FGC38_10700) letA 2127164..2127820 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FGC38_RS23950 - 2127962..2128033 (+) 72 Protein_2103 transcriptional regulator -
  FGC38_RS10705 (FGC38_10705) yecU 2128116..2128292 (+) 177 WP_000590347.1 protein YecU -
  FGC38_RS10710 (FGC38_10710) yecF 2128279..2128503 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  FGC38_RS10715 (FGC38_10715) sdiA 2128571..2129293 (-) 723 WP_001152715.1 transcriptional regulator SdiA -
  FGC38_RS10720 (FGC38_10720) tcyN 2129523..2130275 (-) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FGC38_RS10725 (FGC38_10725) tcyL 2130272..2130940 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  FGC38_RS10730 (FGC38_10730) dcyD 2130955..2131941 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=322613 FGC38_RS10700 WP_000611335.1 2127164..2127820(-) (letA) [Escherichia coli strain BE104]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=322613 FGC38_RS10700 WP_000611335.1 2127164..2127820(-) (letA) [Escherichia coli strain BE104]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486