Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FE252_RS12195 Genome accession   NZ_CP040456
Coordinates   2226870..2227526 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain UPEC132     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2221870..2232526
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE252_RS12165 dcyD 2222749..2223735 (+) 987 WP_001128237.1 D-cysteine desulfhydrase -
  FE252_RS12170 tcyL 2223750..2224418 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FE252_RS12175 tcyN 2224415..2225167 (+) 753 WP_001272998.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FE252_RS12180 sdiA 2225397..2226119 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  FE252_RS12185 yecF 2226187..2226411 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FE252_RS12190 yecU 2226398..2226574 (-) 177 WP_001307856.1 protein YecU -
  FE252_RS12195 letA 2226870..2227526 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FE252_RS12200 uvrC 2227523..2229355 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  FE252_RS12205 pgsA 2229412..2229960 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FE252_RS12225 yecA 2230610..2231275 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=321795 FE252_RS12195 WP_000611328.1 2226870..2227526(+) (letA) [Escherichia coli strain UPEC132]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=321795 FE252_RS12195 WP_000611328.1 2226870..2227526(+) (letA) [Escherichia coli strain UPEC132]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482