Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   FE198_RS10575 Genome accession   NZ_CP040390
Coordinates   2152256..2152912 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain A1_136     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2147256..2157912
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  FE198_RS10540 (FE198_10540) dcyD 2148136..2149122 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  FE198_RS10545 (FE198_10545) tcyL 2149137..2149805 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  FE198_RS10550 (FE198_10550) tcyN 2149802..2150554 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  FE198_RS10555 (FE198_10555) sdiA 2150784..2151506 (+) 723 WP_001154265.1 transcriptional regulator SdiA -
  FE198_RS10560 (FE198_10560) yecF 2151573..2151797 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  FE198_RS10565 (FE198_10565) yecU 2151784..2151960 (-) 177 WP_000590344.1 protein YecU -
  FE198_RS26990 (FE198_10570) - 2151998..2152114 (-) 117 WP_023063716.1 hypothetical protein -
  FE198_RS10575 (FE198_10575) letA 2152256..2152912 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  FE198_RS10580 (FE198_10580) uvrC 2152909..2154741 (+) 1833 WP_060579134.1 excinuclease ABC subunit UvrC Machinery gene
  FE198_RS10585 (FE198_10585) pgsA 2154798..2155346 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  FE198_RS10605 (FE198_10605) yecA 2155996..2156661 (+) 666 WP_000847880.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=321552 FE198_RS10575 WP_000611328.1 2152256..2152912(+) (letA) [Escherichia coli strain A1_136]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=321552 FE198_RS10575 WP_000611328.1 2152256..2152912(+) (letA) [Escherichia coli strain A1_136]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTTGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGTGGTGAAGACGCCGTTAAGTGGTGTCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482